Methylophiopogonanone A suppresses ischemia/reperfusion-induced myocardial apoptosis in mice via activating PI3K/Akt/eNOS signaling pathway

Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade

(2015) Sauri Hernández-Reséndiz et al.   BASIC RESEARCH IN CARDIOLOGY

Nicorandil Protects the Heart from Ischemia/Reperfusion Injury by Attenuating Endoplasmic Reticulum Response-induced Apoptosis Through PI3K/Akt Signaling Pathway

(2015) Hui Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Molecular Basis of Cardioprotection: Signal Transduction in Ischemic Pre-, Post-, and Remote Conditioning

(2015) G. Heusch   CIRCULATION RESEARCH

PPARγ–PI3K/AKT–NO signal pathway is involved in cardiomyocyte hypertrophy induced by high glucose and insulin

(2015) Xiaofeng Peng et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

(2015) Borja Ibáñez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The PI3K/Akt pathway mediates the protection of SO2 preconditioning against myocardial ischemia/reperfusion injury in rats

(2013) Man-man Zhao et al.   ACTA PHARMACOLOGICA SINICA

N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes

(2013) Tingting Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

(2013) Fatih Arslan et al.   Stem Cell Research

Suppression of rat Frizzled-2 attenuates hypoxia/reoxygenation-induced Ca2+ accumulation in rat H9c2 cells

(2012) Shan-shan Zhou et al.   EXPERIMENTAL CELL RESEARCH

Anti-inflammatory homoisoflavonoids from the tuberous roots of Ophiopogon japonicus

(2012) Ning Li et al.   FITOTERAPIA

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca2+ overload and cell death

(2012) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

Inhibition of miR-15 Protects Against Cardiac Ischemic Injury

(2011) Thomas G. Hullinger et al.   CIRCULATION RESEARCH

Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats

(2011) Saurabh Bharti et al.   EUROPEAN JOURNAL OF NUTRITION

Cardiomyocyte death: mechanisms and translational implications

(2011) M Chiong et al.   Cell Death & Disease

Remote postconditioning by humoral factors in effluent from ischemic preconditioned rat hearts is mediated via PI3K/Akt-dependent cell-survival signaling at reperfusion

(2010) L. Breivik et al.   BASIC RESEARCH IN CARDIOLOGY

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

(2010) Y. Cheng et al.   CARDIOVASCULAR RESEARCH

The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury

(2010) Margarita A. Salas et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ischemic post-conditioning reduces infarct size of the in vivo rat heart: role of PI3-K, mTOR, GSK-3β, and apoptosis

(2010) Claudia Wagner et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

An efficient combination of supercritical fluid extraction and high-speed counter-current chromatography to extract and purify homoisoflavonoids fromOphiopogon japonicus(Thunb.) Ker-Gawler

(2009) Chengjun Ma et al.   JOURNAL OF SEPARATION SCIENCE