Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice

Plaque-dependent morphological and electrophysiological heterogeneity of microglia in an Alzheimer's disease mouse model

(2018) Monika Plescher et al.   GLIA

Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice

(2018) Yoelvis García-Mesa et al.   JOURNAL OF ALZHEIMERS DISEASE

The neuron-astrocyte-microglia triad in CA3 after chronic cerebral hypoperfusion in the rat: Protective effect of dipyridamole

(2017) Daniele Lana et al.   EXPERIMENTAL GERONTOLOGY

Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease

(2017) Anna Vilalta et al.   FEBS Journal

Phenotypic Alterations in Hippocampal NPY- and PV-Expressing Interneurons in a Presymptomatic Transgenic Mouse Model of Alzheimer’s Disease

(2017) Ian Mahar et al.   Frontiers in Aging Neuroscience

Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer’s disease

(2017) Valentine Hamm et al.   Science Advances

Early and protective microglial activation in Alzheimer’s disease: a prospective study using18F-DPA-714 PET imaging

(2016) Lorraine Hamelin et al.   BRAIN

Young microglia restore amyloid plaque clearance of aged microglia

(2016) Anna Daria et al.   EMBO JOURNAL

The neuron-astrocyte-microglia triad involvement in neuroinflammaging mechanisms in the CA3 hippocampus of memory-impaired aged rats

(2016) Daniele Lana et al.   EXPERIMENTAL GERONTOLOGY

Microglia in the TBI brain: The good, the bad, and the dysregulated

(2016) David J. Loane et al.   EXPERIMENTAL NEUROLOGY

Clasmatodendrosis and β-amyloidosis in aging hippocampus

(2016) Raffaella Mercatelli et al.   FASEB JOURNAL

Age-related myelin degradation burdens the clearance function of microglia during aging

(2016) Shima Safaiyan et al.   NATURE NEUROSCIENCE

TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model

(2015) Yaming Wang et al.   CELL

White matter injury and microglia/macrophage polarization are strongly linked with age-related long-term deficits in neurological function after stroke

(2015) Jun Suenaga et al.   EXPERIMENTAL NEUROLOGY

Selective Neuronal Vulnerability of Human Hippocampal CA1 Neurons: Lesion Evolution, Temporal Course, and Pattern of Hippocampal Damage in Diffusion-Weighted MR Imaging

(2015) Thorsten Bartsch et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroinflammation in Alzheimer's disease

(2015) Michael T Heneka et al.   LANCET NEUROLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

The integrated role of ACh, ERK and mTOR in the mechanisms of hippocampal inhibitory avoidance memory

(2015) Maria Grazia Giovannini et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Anti-inflammatory Signaling in Microglia Exacerbates Alzheimer’s Disease-Related Pathology

(2015) Jean-Philippe Michaud et al.   NEURON

The hippocampus in aging and disease: From plasticity to vulnerability

(2015) T. Bartsch et al.   NEUROSCIENCE

Astrocyte heterogeneity in the brain: from development to disease

(2015) Clarissa Schitine et al.   Frontiers in Cellular Neuroscience

Memory Consolidation

(2015) Larry R. Squire et al.   Cold Spring Harbor Perspectives in Biology

Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

(2015) Marilia S. Albuquerque et al.   Frontiers in Aging Neuroscience

Interleukin-10 may protect against progressing injury during the acute phase of ischemic stroke

(2014) Gustavo G. Protti et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

(2014) Marco Prinz et al.   NATURE REVIEWS NEUROSCIENCE

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Astrogliosis as a therapeutic target for neurodegenerative diseases

(2014) Anna Maria Colangelo et al.   NEUROSCIENCE LETTERS

The dual role of astrocyte activation and reactive gliosis

(2014) Milos Pekny et al.   NEUROSCIENCE LETTERS

Astrocyte-Derived Proinflammatory Cytokines Induce Hypomyelination in the Periventricular White Matter in the Hypoxic Neonatal Brain

(2014) Yiyu Deng et al.   PLoS One

Human Astrocytes: Secretome Profiles of Cytokines and Chemokines

(2014) Sung S. Choi et al.   PLoS One

The neuron-astrocyte-microglia triad in a rat model of chronic cerebral hypoperfusion: protective effect of dipyridamole

(2014) Daniele Lana et al.   Frontiers in Aging Neuroscience

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system

(2013) Dorothy P. Schafer et al.   CURRENT OPINION IN NEUROBIOLOGY

Hippocampal long term memory: Effect of the cholinergic system on local protein synthesis

(2013) Daniele Lana et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Amyloid-Beta Induced CA1 Pyramidal Cell Loss in Young Adult Rats Is Alleviated by Systemic Treatment with FGL, a Neural Cell Adhesion Molecule-Derived Mimetic Peptide

(2013) Nicola J. Corbett et al.   PLoS One

Microglia and Inflammation in Alzheimers Disease

(2012) Shweta Mandrekar-Colucci et al.   CNS & Neurological Disorders-Drug Targets

Total daily physical activity and the risk of AD and cognitive decline in older adults

(2012) A.S. Buchman et al.   NEUROLOGY

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The Neuron-Astrocyte-Microglia Triad in Normal Brain Ageing and in a Model of Neuroinflammation in the Rat Hippocampus

(2012) Francesca Cerbai et al.   PLoS One

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Microglia: actively surveying and shaping neuronal circuit structure and function

(2012) Hiroaki Wake et al.   TRENDS IN NEUROSCIENCES

Primary Phagocytosis of Neurons by Inflamed Microglia: Potential Roles in Neurodegeneration

(2012) Jonas J. Neher et al.   Frontiers in Pharmacology

Early Astrocytic Atrophy in the Entorhinal Cortex of a Triple Transgenic Animal Model of Alzheimer's Disease

(2011) Chia-Yu Yeh et al.   ASN Neuro

Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis

(2011) D. Fitzner et al.   JOURNAL OF CELL SCIENCE

Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

(2011) Marco Prinz et al.   NATURE NEUROSCIENCE

A pathophysiological framework of hippocampal dysfunction in ageing and disease

(2011) Scott A. Small et al.   NATURE REVIEWS NEUROSCIENCE

Aβ plaque-associated glial reaction as a determinant of apoptotic neuronal death and cortical gliogenesis: A study in APP mutant mice

(2011) Ilaria Luccarini et al.   NEUROSCIENCE LETTERS

Reversal of Glial and Neurovascular Markers of Unhealthy Brain Aging by Exercise in Middle-Aged Female Mice

(2011) Caitlin S. Latimer et al.   PLoS One

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Where the thoughts dwell: The physiology of neuronal–glial “diffuse neural net”

(2010) Alexei Verkhratsky et al.   BRAIN RESEARCH REVIEWS

Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease

(2010) Susanne G. Mueller et al.   HUMAN BRAIN MAPPING

Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRI

(2010) G. A. Kerchner et al.   NEUROLOGY

Reactive astrocytes as therapeutic targets for CNS disorders

(2010) Mary E. Hamby et al.   Neurotherapeutics

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

(2009) Wolfgang J. Streit et al.   ACTA NEUROPATHOLOGICA

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

Neuroglia in neurodegeneration

(2009) Michael T. Heneka et al.   BRAIN RESEARCH REVIEWS

Role of glial cells in the formation and maintenance of synapses

(2009) Frank W. Pfrieger   BRAIN RESEARCH REVIEWS

In vivoover-expression of interleukin-10 increases resistance to focal brain ischemia in mice

(2009) Fabienne de Bilbao et al.   JOURNAL OF NEUROCHEMISTRY

Neuroscience: Glia — more than just brain glue

(2009) Nicola J. Allen et al.   NATURE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Astroglia in dementia and Alzheimer's disease

(2008) J J Rodríguez et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial dynamics and apoptosis

(2008) D.-F. Suen et al.   GENES & DEVELOPMENT

Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease

(2008) D. Farfara et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dynamics of the Microglial/Amyloid Interaction Indicate a Role in Plaque Maintenance

(2008) T. Bolmont et al.   JOURNAL OF NEUROSCIENCE

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE

Pathological and protective roles of glia in chronic pain

(2008) Erin D. Milligan et al.   NATURE REVIEWS NEUROSCIENCE

Aged wild-type and APP, PS1, and APP+PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load

(2008) A. Gruart et al.   NEUROBIOLOGY OF DISEASE

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

(2008) Ben A. Barres   NEURON

Differential activation of mitogen-activated protein kinase signalling pathways in the hippocampus of CRND8 transgenic mouse, a model of Alzheimer's disease

(2008) M.G. Giovannini et al.   NEUROSCIENCE

Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders

(2007) Jacques De Keyser et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES