Novel CHOP activator LGH00168 induces necroptosis in A549 human lung cancer cells via ROS-mediated ER stress and NF-κB inhibition

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(2015) Joan Minguet et al.   INTERNATIONAL JOURNAL OF CANCER

Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP

(2015) Jiao Yang et al.   STRUCTURE

Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells

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RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3

(2014) Christopher P. Dillon et al.   CELL

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(2014) Robert Pirker   CURRENT OPINION IN ONCOLOGY

Discovery of 2′-hydroxychalcones as autophagy inducer in A549 lung cancer cells

(2014) Fang-Wu Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

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(2014) Kurt D. Marshall et al.   Frontiers in Physiology

New directions in ER stress-induced cell death

(2013) Susan E. Logue et al.   APOPTOSIS

The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma

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(2013) R. J. Thapa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

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(2013) H. Walczak   Cold Spring Harbor Perspectives in Biology

CHOP is a multifunctional transcription factor in the ER stress response

(2012) H. Nishitoh   JOURNAL OF BIOCHEMISTRY

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First-Line Systemic Chemotherapy in the Treatment of Advanced Non-small Cell Lung Cancer: A Systematic Review

(2010) John Goffin et al.   Journal of Thoracic Oncology

Apoptotic cell death "Nixed" by an ER-mitochondrial necrotic pathway

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High-Throughput Assay for Modulators of Mitochondrial Membrane Potential Identifies a Novel Compound With Beneficial Effects on db/db Mice

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(2009) Maria Eugenia Guicciardi et al.   FASEB JOURNAL

Inhibition of the ER Ca 2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis

(2009) Katja Janssen et al.   JOURNAL OF CELL SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

ATP depletion alters the mode of cell death induced by benzyl isothiocyanate

(2008) Noriyuki Miyoshi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cell Death by Necrosis, a Regulated Way to Go

(2008) Mauricio Henriquez et al.   CURRENT MOLECULAR MEDICINE

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

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