Hemolysis in human erythrocytes by Clostridium perfringens epsilon toxin requires activation of P2 receptors

Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel

(2017) Go Kasuya et al.   Nature Communications

F199E substitution reduced toxicity of Clostridium perfringens epsilon toxin by depriving the receptor binding capability

(2017) Jingjing Kang et al.   Human Vaccines & Immunotherapeutics

Blood cells: an historical account of the roles of purinergic signalling

(2015) Geoffrey Burnstock   Purinergic Signalling

Propensity of red blood cells to undergo P2X7 receptor-mediated phosphatidylserine exposure does not alter during in vivo or ex vivo aging

(2015) Reece A. Sophocleous et al.   TRANSFUSION

Clostridium perfringens epsilon toxin: The third most potent bacterial toxin known

(2014) Guilherme Guerra Alves et al.   ANAEROBE

Hemolysis is a primary ATP-release mechanism in human erythrocytes

(2014) J. Sikora et al.   BLOOD

Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore

(2014) Marianne Skals et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxin Plasmids of Clostridium perfringens

(2013) J. Li et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A low-toxic site-directed mutant ofClostridium perfringensε-toxin as a potential candidate vaccine against enterotoxemia

(2013) Qing Li et al.   Human Vaccines & Immunotherapeutics

Clostridium perfringens Epsilon Toxin: A Malevolent Molecule for Animals and Man?

(2013) Bradley Stiles et al.   Toxins

Leukotoxin fromAggregatibacter actinomycetemcomitanscauses shrinkage and P2X receptor-dependent lysis of human erythrocytes

(2012) Peter Svenssen Munksgaard et al.   CELLULAR MICROBIOLOGY

Molecular and functional properties of P2X receptors—recent progress and persisting challenges

(2012) Karina Kaczmarek-Hájek et al.   Purinergic Signalling

Molecular basis of toxicity of Clostridium perfringens epsilon toxin

(2011) Monika Bokori-Brown et al.   FEBS Journal

Haemolysis induced by α-toxin from Staphylococcus aureus requires P2X receptor activation

(2011) Marianne Skals et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Gene-Trap Mutagenesis Identifies Mammalian Genes Contributing to Intoxication by Clostridium perfringens ε-Toxin

(2011) Susan E. Ivie et al.   PLoS One

Expression and purification of functional Clostridium perfringens alpha and epsilon toxins in Escherichia coli

(2011) Yao Zhao et al.   PROTEIN EXPRESSION AND PURIFICATION

Clostridium perfringens Epsilon Toxin Increases the Small Intestinal Permeability in Mice and Rats

(2009) Jorge Goldstein et al.   PLoS One

 -Hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis

(2009) M. Skals et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probenecid, a gout remedy, inhibits pannexin 1 channels

(2008) William Silverman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts

(2008) P. Gonnord et al.   FASEB JOURNAL