Assessing the function of pneumococcal neuraminidases NanA, NanB and NanC in in vitro and in vivo lung infection models using monoclonal antibodies

Deacetylation of sialic acid by esterases potentiates pneumococcal neuraminidase activity for mucin utilization, colonization and virulence

(2017) Hasan F. Kahya et al.   PLoS Pathogens

Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR

(2016) Karina Hentrich et al.   Cell Host & Microbe

Biological and Epidemiological Features of Antibiotic-Resistant Streptococcus pneumoniae in Pre- and Post-Conjugate Vaccine Eras: a United States Perspective

(2016) Lindsay Kim et al.   CLINICAL MICROBIOLOGY REVIEWS

Neuraminidase A-Exposed Galactose Promotes Streptococcus pneumoniae Biofilm Formation during Colonization

(2016) Krystle A. Blanchette et al.   INFECTION AND IMMUNITY

Defining the role of pneumococcal neuraminidases and O-glycosidase in pneumococcal haemolytic uraemic syndrome

(2016) Anirudh K. Singh et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Low Serum Fetuin-A as a Biomarker to Predict Pneumococcal Necrotizing Pneumonia and Hemolytic Uremic Syndrome in Children

(2016) Rajendra Prasad Janapatla et al.   MEDICINE

Nonencapsulated Streptococcus pneumoniae : Emergence and Pathogenesis

(2016) Lance E. Keller et al.   mBio

Variation in Carbohydrates between Cancer and Normal Cell Membranes Revealed by Super-Resolution Fluorescence Imaging

(2016) Junling Chen et al.   Advanced Science

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

(2016) Valentina Cappello et al.   Scientific Reports

Antipneumococcal activity of neuraminidase inhibiting artocarpin

(2015) E. Walther et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Streptococcus pneumoniaeNanC

(2015) C. David Owen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of the 13-valent pneumococcal conjugate vaccine on invasive pneumococcal disease in England and Wales 4 years after its introduction: an observational cohort study

(2015) Pauline A Waight et al.   LANCET INFECTIOUS DISEASES

Polysaccharide Conjugate Vaccine against Pneumococcal Pneumonia in Adults

(2015) Marc J.M. Bonten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Structural importance of the C-terminal region in pig aldo-keto reductase family 1 member C1 and their effects on enzymatic activity

(2015) Minky Son et al.   BMC STRUCTURAL BIOLOGY

Next generation protein basedStreptococcus pneumoniaevaccines

(2015) Michael E Pichichero et al.   Human Vaccines & Immunotherapeutics

Transcriptional and metabolic effects of glucose on Streptococcus pneumoniae sugar metabolism

(2015) Laura Paixão et al.   Frontiers in Microbiology

Virulence Factors of Streptococcus pneumoniae. Comparison between African and French Invasive Isolates and Implication for Future Vaccines

(2015) Sophie Blumental et al.   PLoS One

Sialic acid-dependent attachment of mucins from three mouse strains to Entamoeba histolytica

(2013) Kentaro Kato et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Investigating the role of pneumococcal neuraminidase A activity in isolates from pneumococcal haemolytic uraemic syndrome

(2013) A. Smith et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool

(2013) Y. Xu et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Optimization of a direct spectrophotometric method to investigate the kinetics and inhibition of sialidases

(2012) Jasvinder Hayre et al.   BMC BIOCHEMISTRY

Pneumococcal Pneumonia

(2012) David H. Dockrell et al.   CHEST

Necrotizing pneumonia caused by nanC-carrying serotypes is associated with pneumococcal haemolytic uraemic syndrome in children

(2012) R.-P. Janapatla et al.   CLINICAL MICROBIOLOGY AND INFECTION

Pneumococcal neuraminidase A: an essential upper airway colonization factor for Streptococcus pneumoniae

(2012) J.L. Brittan et al.   Molecular Oral Microbiology

Leukocyte Inflammatory Responses Provoked by Pneumococcal Sialidase

(2012) Y.-C. Chang et al.   mBio

ThreeStreptococcus pneumoniaeSialidases: Three Different Products

(2011) Guogang Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Serotype replacement in disease after pneumococcal vaccination

(2011) Daniel M Weinberger et al.   LANCET

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Secretion-and-capture cell-surface display for selection of target-binding proteins

(2011) J. A. Rakestraw et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Pneumococcal vaccination in adults: Does it really work?

(2011) Georgia G. Pitsiou et al.   RESPIRATORY MEDICINE

Streptococcus pneumoniae: virulence factors and variation

(2010) A.M. Mitchell et al.   CLINICAL MICROBIOLOGY AND INFECTION

Distribution and clonal relationship of cell surface virulence genes among Streptococcus pneumoniae isolates in Japan

(2010) S. Imai et al.   CLINICAL MICROBIOLOGY AND INFECTION

Three Surface Exoglycosidases from Streptococcus pneumoniae, NanA, BgaA, and StrH, Promote Resistance to Opsonophagocytic Killing by Human Neutrophils

(2010) A. B. Dalia et al.   INFECTION AND IMMUNITY

Sialic Acid Transport Contributes to Pneumococcal Colonization

(2010) Carolyn Marion et al.   INFECTION AND IMMUNITY

Genotypic and phenotypic characterisation of invasive Streptococcus pneumoniae isolates from Hungary, and coverage of the conjugate vaccines

(2010) O. Dobay et al.   JOURNAL OF CLINICAL PATHOLOGY

Identification of novel pneumolysin alleles from paediatric carriage isolates of Streptococcus pneumoniae

(2010) J. M. C. Jefferies et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Pneumococcal modification of host sugars: a major contributor to colonization of the human airway?

(2010) S.J. King   Molecular Oral Microbiology

Crystal structures of respiratory pathogen neuraminidases

(2009) Yu-Shan Hsiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The NanA Neuraminidase of Streptococcus pneumoniae Is Involved in Biofilm Formation

(2009) D. Parker et al.   INFECTION AND IMMUNITY

The surface-anchored NanA protein promotes pneumococcal brain endothelial cell invasion

(2009) Satoshi Uchiyama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pneumococcal Surface Protein A Contributes to SecondaryStreptococcus pneumoniaeInfection after Influenza Virus Infection

(2009) Quinton O. King et al.   JOURNAL OF INFECTIOUS DISEASES

Sialic Acid: A Preventable Signal for Pneumococcal Biofilm Formation, Colonization, and Invasion of the Host

(2009) Claudia Trappetti et al.   JOURNAL OF INFECTIOUS DISEASES

Vaccines: Pneumococcal Vaccination of Elderly Adults: New Paradigms for Protection

(2008) Lisa A. Jackson et al.   CLINICAL INFECTIOUS DISEASES

Structural and functional studies ofStreptococcus pneumoniaeneuraminidase B: An intramoleculartrans-sialidase

(2008) Heinz Gut et al.   FEBS LETTERS

The ability to utilize mucin affects the regulation of virulence gene expression inStreptococcus pneumoniae

(2008) Hasan Yesilkaya et al.   FEMS MICROBIOLOGY LETTERS

Crystal Structure of the NanB Sialidase from Streptococcus pneumoniae

(2008) Guogang Xu et al.   JOURNAL OF MOLECULAR BIOLOGY

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH