A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells

The sVEGFR1-i13 splice variant regulates a β1 integrin/VEGFR autocrine loop involved in the progression and the response to anti-angiogenic therapies of squamous cell lung carcinoma

(2018) Cherine Abou Faycal et al.   BRITISH JOURNAL OF CANCER

Splice Variants of the RTK Family: Their Role in Tumour Progression and Response to Targeted Therapy

(2017) Cherine Abou-Fayçal et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ground rules of the pluripotency gene regulatory network

(2017) Mo Li et al.   NATURE REVIEWS GENETICS

The Soluble VEGF Receptor sFlt-1 Contributes to Impaired Neovascularization in Aged Mice

(2017) Guangxian Zhao et al.   Aging and Disease

Jumonji Domain Containing Protein 6 Is Decreased in Human Preeclamptic Placentas and Regulates sFLT-1 Splice Variant Production1

(2016) Kirsten R. Palmer et al.   BIOLOGY OF REPRODUCTION

Genetic alteration profiling of patients with resected squamous cell lung carcinomas

(2016) Dan Tao et al.   Oncotarget

Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer

(2015) Rebecca S. Heist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients

(2015) Sara M. Tolaney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative Splicing of MBD2 Supports Self-Renewal in Human Pluripotent Stem Cells

(2014) Yu Lu et al.   Cell Stem Cell

Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype

(2014) M. Larrayoz et al.   EMBO Molecular Medicine

The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2

(2014) Xia Xu et al.   GENES & DEVELOPMENT

VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2

(2014) D Zhao et al.   ONCOGENE

NOTCH Decoys That Selectively Block DLL/NOTCH or JAG/NOTCH Disrupt Angiogenesis by Unique Mechanisms to Inhibit Tumor Growth

(2014) Thaned Kangsamaksin et al.   Cancer Discovery

A Phase II and Biomarker Study of Ramucirumab, a Human Monoclonal Antibody Targeting the VEGF Receptor-2, as First-Line Monotherapy in Patients with Advanced Hepatocellular Cancer

(2013) A. X. Zhu et al.   CLINICAL CANCER RESEARCH

VEGF-A induces its negative regulator, soluble form of VEGFR-1, by modulating its alternative splicing

(2013) Tetsuya Saito et al.   FEBS LETTERS

Phase I Study of Cetuximab, Irinotecan, and Vandetanib (ZD6474) as Therapy for Patients with Previously Treated Metastastic Colorectal Cancer

(2012) Jeffrey A. Meyerhardt et al.   PLoS One

Abnormal Expression of the Pre-mRNA Splicing Regulators SRSF1, SRSF2, SRPK1 and SRPK2 in Non Small Cell Lung Carcinoma

(2012) Stephanie Gout et al.   PLoS One

International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma

(2011) William D. Travis et al.   Journal of Thoracic Oncology

Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1

(2011) J.-N. Boeckel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasma Soluble VEGFR-1 Is a Potential Dual Biomarker of Response and Toxicity for Bevacizumab with Chemoradiation in Locally Advanced Rectal Cancer

(2010) D. G. Duda et al.   ONCOLOGIST

A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia

(2009) Christie P. Thomas et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Efficacy, Safety, and Biomarkers of Neoadjuvant Bevacizumab, Radiation Therapy, and Fluorouracil in Rectal Cancer: A Multidisciplinary Phase II Study

(2009) Christopher G. Willett et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Trial of Infusional Fluorouracil, Irinotecan, and Bevacizumab for Metastatic Colorectal Cancer: Efficacy and Circulating Angiogenic Biomarkers Associated With Therapeutic Resistance

(2009) Scott Kopetz et al.   JOURNAL OF CLINICAL ONCOLOGY

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through  5 1 integrin

(2008) S. Soro et al.   BLOOD

E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35

(2008) G Merdzhanova et al.   CELL DEATH AND DIFFERENTIATION