PD-1/PD-L1 Pathway Modulates Macrophage Susceptibility to Mycobacterium tuberculosis Specific CD8+ T cell Induced Death

Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8 + T Cells

(2018) Jing Li et al.   IMMUNITY

Genetic abrogation of immune checkpoints in antigen-specific cytotoxic T-lymphocyte as a potential alternative to blockade immunotherapy

(2018) Chi Zhang et al.   Scientific Reports

G-Protein Coupled Receptor 18 Contributes to Establishment of the CD8 Effector T Cell Compartment

(2018) Hayakazu Sumida et al.   Frontiers in Immunology

Mycobacterium tuberculosis Virulent Factor ESAT-6 Drives Macrophage Differentiation Toward the Pro-inflammatory M1 Phenotype and Subsequently Switches It to the Anti-inflammatory M2 Phenotype

(2018) Amira Refai et al.   Frontiers in Cellular and Infection Microbiology

Transcriptome analysis of IL-10-stimulated (M2c) macrophages by next-generation sequencing

(2017) Emily B. Lurier et al.   IMMUNOBIOLOGY

T Cell–Derived IL-10 Impairs Host Resistance toMycobacterium tuberculosisInfection

(2017) Lúcia Moreira-Teixeira et al.   JOURNAL OF IMMUNOLOGY

CMV-Specific T-cell Responses at Older Ages: Broad Responses With a Large Central Memory Component May Be Key to Long-term Survival

(2017) Martha Bajwa et al.   JOURNAL OF INFECTIOUS DISEASES

MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+ T cells and contributes to protection against infection

(2017) Yao Bian et al.   PLoS Pathogens

Lipoarabinomannan, and its related glycolipids, induce divergent and opposing immune responses to Mycobacterium tuberculosis depending on structural diversity and experimental variations

(2016) Gunilla Källenius et al.   TUBERCULOSIS

Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections

(2016) Yun-Ji Lim et al.   Scientific Reports

HIV-TB coinfection impairs CD8+T-cell differentiation and function while dehydroepiandrosterone improves cytotoxic antitubercular immune responses

(2015) Guadalupe V. Suarez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting CD64 mediates elimination of M1 but not M2 macrophages in vitro and in cutaneous inflammation in mice and patient biopsies

(2015) Dmitrij Hristodorov et al.   mAbs

Mycobacterium tuberculosis-Induced Polarization of Human Macrophage Orchestrates the Formation and Development of Tuberculous Granulomas In Vitro

(2015) Zikun Huang et al.   PLoS One

Programmed cell death 1 (PD-1) regulates the effector function of CD8 T cells via PD-L1 expressed on target keratinocytes

(2014) Naoko Okiyama et al.   JOURNAL OF AUTOIMMUNITY

Programmed Death (PD)-1:PD-Ligand 1/PD-Ligand 2 Pathway Inhibits T Cell Effector Functions during Human Tuberculosis

(2014) J. O. Jurado et al.   JOURNAL OF IMMUNOLOGY

Early Skewed Distribution of Total and HIV-Specific CD8+ T-Cell Memory Phenotypes during Primary HIV Infection Is Related to Reduced Antiviral Activity and Faster Disease Progression

(2014) Yanina Ghiglione et al.   PLoS One

T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection

(2014) Marcus Buggert et al.   PLoS Pathogens

Understanding the Biology of Antigen Cross-Presentation for the Design of Vaccines Against Cancer

(2014) Cynthia M. Fehres et al.   Frontiers in Immunology

Mycobacterium tuberculosis-specific CD8+T cells are functionally and phenotypically different between latent infection and active disease

(2013) Virginie Rozot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

Systematic validation of specific phenotypic markers for in vitro polarized human macrophages

(2011) C.A. Ambarus et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin Expression on M2-Polarized and Tumor-Associated Macrophages Is Macrophage-CSF Dependent and Enhanced by Tumor-Derived IL-6 and IL-10

(2011) A. Dominguez-Soto et al.   JOURNAL OF IMMUNOLOGY

Phenotype, Function, and Gene Expression Profiles of Programmed Death-1 hi CD8 T Cells in Healthy Human Adults

(2011) Jaikumar Duraiswamy et al.   JOURNAL OF IMMUNOLOGY

CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1-Mediated Inhibition

(2010) D. L. Barber et al.   JOURNAL OF IMMUNOLOGY

Role Played by the Programmed Death‐1–Programmed Death Ligand Pathway during Innate Immunity againstMycobacterium tuberculosis

(2010) Ivana B. Alvarez et al.   JOURNAL OF INFECTIOUS DISEASES

Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?

(2010) Samuel M. Behar et al.   NATURE REVIEWS MICROBIOLOGY

Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis

(2010) E. Lazar-Molnar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update on tuberculous pleural effusion

(2010) Richard W. LIGHT   RESPIROLOGY

Interferon-γ reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

(2009) Dorothée Duluc et al.   INTERNATIONAL JOURNAL OF CANCER

Anti-TNF immunotherapy reduces CD8+ T cell–mediated antimicrobial activity against Mycobacterium tuberculosis in humans

(2009) Heiko Bruns et al.   JOURNAL OF CLINICAL INVESTIGATION

Phenotype and function of human T lymphocyte subsets: Consensus and issues

(2008) Victor Appay et al.   CYTOMETRY PART A