Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

Triterpenes and meroterpenes from Ganoderma lucidum with inhibitory activity against HMGs reductase, aldose reductase and α-glucosidase

(2017) Baosong Chen et al.   FITOTERAPIA

Phytochemical Analysis of Agrimonia pilosa Ledeb, Its Antioxidant Activity and Aldose Reductase Inhibitory Potential

(2017) Set Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gigantol from Dendrobium chrysotoxum Lindl. binds and inhibits aldose reductase gene to exert its anti-cataract activity: An in vitro mechanistic study

(2017) Jie Wu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cataracts

(2017) Yu-Chi Liu et al.   LANCET

Chemical Constituents of Smilax china L. Stems and Their Inhibitory Activities against Glycation, Aldose Reductase, α-Glucosidase, and Lipase

(2017) Hee Lee et al.   MOLECULES

Characterization of DHDP, a novel aldose reductase inhibitor isolated from Lysimachia christinae

(2017) Zhiqiang Wang et al.   Journal of Functional Foods

Morinda citrifolia (Noni): A comprehensive review on its industrial uses, pharmacological activities, and clinical trials

(2017) Reem Abou Assi et al.   Arabian Journal of Chemistry

Rapid Identification and Isolation of Inhibitors of Rat Lens Aldose Reductase and Antioxidant in Maackia amurensis

(2017) Set Byeol Kim et al.   Biomed Research International

Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds

(2017) Yoon Kyoung Lee et al.   Biomed Research International

Inhibitory Activities ofStauntonia hexaphyllaLeaf Constituents on Rat Lens Aldose Reductase and Formation of Advanced Glycation End Products and Antioxidant

(2017) Seung Hwan Hwang et al.   Biomed Research International

Determination of flavonoids from Perilla frutescens var. japonica seeds and their inhibitory effect on aldose reductase

(2017) Jaemin Lee et al.   Applied Biological Chemistry

Lupeol, a pentacyclic triterpenoid isolated from Vernonia cinerea attenuate selenite induced cataract formation in Sprague Dawley rat pups

(2016) Radha Asha et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anticataractogenic Activity of Luteolin

(2016) Salvatore Chirumbolo   CHEMISTRY & BIODIVERSITY

Medical Application ofSpirulina platensisDerived C-Phycocyanin

(2016) Qian Liu et al.   Evidence-based Complementary and Alternative Medicine

Isolation, modification, and aldose reductase inhibitory activity of rosmarinic acid derivatives from the roots of Salvia grandifolia

(2016) Jie Kang et al.   FITOTERAPIA

Emblica officinalis (Amla): A review for its phytochemistry, ethnomedicinal uses and medicinal potentials with respect to molecular mechanisms

(2016) Bhavesh C. Variya et al.   PHARMACOLOGICAL RESEARCH

Flavonoids from Litsea japonica Inhibit AGEs Formation and Rat Lense Aldose Reductase In Vitro and Vessel Dilation in Zebrafish

(2016) Ik-Soo Lee et al.   PLANTA MEDICA

Aldose reductase expression as a risk factor for cataract

(2015) Anson Snow et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anti-osmotic and antioxidant activities of gigantol from Dendrobium aurantiacum var. denneanum against cataractogenesis in galactosemic rats

(2015) Hua Fang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Phenolic Compounds from the Leaves and Twigs of Osteomeles schwerinae That Inhibit Rat Lens Aldose Reductase and Vessel Dilation in Zebrafish Larvae

(2015) Ik-Soo Lee et al.   JOURNAL OF NATURAL PRODUCTS

Metabolites identification of bioactive licorice compounds in rats

(2015) Qi Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Aldose reductase and protein tyrosine phosphatase 1B inhibitory active compounds fromSyzygium cuminiseeds

(2015) Laxman Sawant et al.   PHARMACEUTICAL BIOLOGY

The inhibitory activity of aldose reductase in vitro by constituents of Garcinia mangostana Linn

(2015) Sri Fatmawati et al.   PHYTOMEDICINE

Preparative isolation of aldose reductase inhibitory compounds from Nardostachys chinensis by elution–extrusion counter-current chromatography

(2014) Ji Hun Paek et al.   ARCHIVES OF PHARMACAL RESEARCH

Identification of the metabolites of gigantol in rat urine by ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

(2014) Yuanmin Fan et al.   BIOMEDICAL CHROMATOGRAPHY

20( S )-Ginsenoside Rh2 as aldose reductase inhibitor from Panax ginseng

(2014) Sri Fatmawati et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Xanthones fromSwertia mussotiias Multitarget-Directed Antidiabetic Agents

(2014) Huan-Huan Zheng et al.   ChemMedChem

Structure of constituents isolated from the flower buds of Cananga odorata and their inhibitory effects on aldose reductase

(2014) Takahiro Matsumoto et al.   Journal of Natural Medicines

Inhibitory Effects of Colocasia esculenta (L.) Schott Constituents on Aldose Reductase

(2014) Hong Li et al.   MOLECULES

Evaluation of Neonatal Streptozotocin Induced Diabetic Rat Model for the Development of Cataract

(2014) Madhoosudan A. Patil et al.   Oxidative Medicine and Cellular Longevity

Inhibitory effect of banana (Musa sp. var. Nanjangud rasa bale) flower extract and its constituents Umbelliferone and Lupeol on α-glucosidase, aldose reductase and glycation at multiple stages

(2014) Ramith Ramu et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Analysis of the inhibitory activity of Abeliophyllum distichum leaf constituents against aldose reductase by using high-speed counter current chromatography

(2013) Hong Mei Li et al.   ARCHIVES OF PHARMACAL RESEARCH

Aldose Reductase Inhibitory Compounds from Xanthium strumarium

(2013) Ha Na Yoon et al.   ARCHIVES OF PHARMACAL RESEARCH

Structure–activity relationships of lanostane-type triterpenoids from Ganoderma lingzhi as α-glucosidase inhibitors

(2013) Sri Fatmawati et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aldose reductase inhibitory compounds from extracts of Dipsacus asper

(2013) Dong Chil Koo et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Effects of Allium victorialis leaf extracts and its single compounds on aldose reductase, advanced glycation end products and TGF-β1 expression in mesangial cells

(2013) Young Sook Kim et al.   BMC Complementary and Alternative Medicine

Medicinal Flowers. XXXX.1) Structures of Dihydroisocoumarin Glycosides and Inhibitory Effects on Aldose Reducatase from the Flowers of Hydrangea macrophylla var. thunbergii

(2013) Jiang Liu et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Medicinal Flowers. XXXVIII. Structures of Acylated Sucroses and Inhibitory Effects of Constituents on Aldose Reducatase from the Flower Buds of Prunus mume

(2013) Katsuyoshi Fujimoto et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

2″,4″-O-Diacetylquercitrin, a Novel Advanced Glycation End-Product Formation and Aldose Reductase Inhibitor from Melastoma sanguineum

(2013) Ik-Soo Lee et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

The inhibitory activities of the edible green alga Capsosiphon fulvescens on rat lens aldose reductase and advanced glycation end products formation

(2013) Md. Nurul Islam et al.   EUROPEAN JOURNAL OF NUTRITION

Caffeine eye drops protect against UV-B cataract

(2013) Martin Kronschläger et al.   EXPERIMENTAL EYE RESEARCH

Phenolic glycosides and other constituents from the bark ofMagnolia officinalis

(2013) Ren-Yi Yan et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Structures of acylated sucroses and an acylated flavonol glycoside and inhibitory effects of constituents on aldose reductase from the flower buds of Prunus mume

(2013) Seikou Nakamura et al.   Journal of Natural Medicines

Caffeoylated Phenylpropanoid Glycosides from Brandisia hancei Inhibit Advanced Glycation End Product Formation and Aldose Reductase in Vitro and Vessel Dilation in Larval Zebrafish in Vivo

(2013) Song Yu et al.   PLANTA MEDICA

Rapid Identification of Aldose Reductase Inhibitory Compounds fromPerilla frutescens

(2013) Ji Hun Paek et al.   Biomed Research International

Inhibitory activity of Aralia continentalis roots on protein tyrosine phosphatase 1B and rat lens aldose reductase

(2012) Hee Jin Jung et al.   ARCHIVES OF PHARMACAL RESEARCH

C-Phycocyanin Modulates Selenite-Induced Cataractogenesis in Rats

(2012) Rasiah Pratheepa Kumari et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Prevention of selenite induced oxidative stress and cataractogenesis by luteolin isolated from Vitex negundo

(2012) B.N. Rooban et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Beta-glucogallin reduces the expression of lipopolysaccharide-induced inflammatory markers by inhibition of aldose reductase in murine macrophages and ocular tissues

(2012) Kun-Che Chang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Chemical Components of Dendrobium chrysotoxum

(2012) Jiangmiao Hu et al.   CHINESE JOURNAL OF CHEMISTRY

Syringic Acid Extracted fromHerba dendrobiiPrevents Diabetic Cataract Pathogenesis by Inhibiting Aldose Reductase Activity

(2012) Xiaoyong Wei et al.   Evidence-based Complementary and Alternative Medicine

Isolation and identification of phenolic compounds from the seeds of Perilla frutescens (L.) and their inhibitory activities against α-glucosidase and aldose reductase

(2012) Tae Joung Ha et al.   FOOD CHEMISTRY

The Inhibitory Effect ofPrunella vulgarisL. on Aldose Reductase and Protein Glycation

(2012) Hong Mei Li et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Chemical Constituents from the Aerial Parts of Aster koraiensis with Protein Glycation and Aldose Reductase Inhibitory Activities

(2012) Jun Lee et al.   JOURNAL OF NATURAL PRODUCTS

Sulfuretin, a major flavonoid isolated from Rhus verniciflua, ameliorates experimental arthritis in mice

(2012) Young-Rae Lee et al.   LIFE SCIENCES

Isoquinoline Alkaloids from Tinospora cordifolia Inhibit Rat Lens Aldose Reductase

(2012) Mayurkumar B. Patel et al.   PHYTOTHERAPY RESEARCH

The Isolation and Characterization of β-Glucogallin as a Novel Aldose Reductase Inhibitor from Emblica officinalis

(2012) Muthenna Puppala et al.   PLoS One

Phycocyanin may suppress d-galactose-induced human lens epithelial cell apoptosis through mitochondrial and unfolded protein response pathways

(2012) Yu Ou et al.   TOXICOLOGY LETTERS

Inhibition of Aldose Reductase by Phenylethanoid Glycoside Isolated from the Seeds of Paulownia coreana

(2011) Jin Kyu Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Galloyl Glucoses from the Seeds of Cornus officinalis with Inhibitory Activity against Protein Glycation, Aldose Reductase, and Cataractogenesis ex Vivo

(2011) Jun Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Antidiabetogenic oligostilbenoids and 3-ethyl-4-phenyl-3,4-dihydroisocoumarins from the bark of Shorea roxburghii

(2011) Toshio Morikawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

α-Glucosidase and Aldose Reductase Inhibitory Activities from the Fruiting Body ofPhellinus merrillii

(2011) Guan-Jhong Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Constituents of the Stem of Angelica gigas with Rat Lens Aldose Reductase Inhibitory Activity

(2011) Hyun Young Park   Journal of the Korean Society for Applied Biological Chemistry

Antidiabetic activity of phenolic compounds from Pecan bark in streptozotocin-induced diabetic rats

(2011) Hossam M. Abdallah et al.   Phytochemistry Letters

Anthraquinones from the Roots of Knoxia valerianoides inhibit the formation of advanced glycation end products and rat lens aldose reductase in vitro

(2010) Nam Hee Yoo et al.   ARCHIVES OF PHARMACAL RESEARCH

Constituents of the flowers of Platycodon grandiflorum with inhibitory activity on advanced glycation end products and rat lens aldose reductase in vitro

(2010) Dae Sik Jang et al.   ARCHIVES OF PHARMACAL RESEARCH

Scopoletin from the flower buds of Magnolia fargesii inhibits protein glycation, aldose reductase, and cataractogenesis Ex Vivo

(2010) Jun Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

Inhibition of Aldose Reductase and Xylose-Induced Lens Opacity by Puerariafuran from the Roots of Pueraria lobata

(2010) Nan Hee Kim et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Aldose Reductase Inhibitory Compounds from Glycyrrhiza uralensis

(2010) Yeon Sil Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

3,5-Di-O-caffeoyl-epi-quinic Acid from the Leaves and Stems of Erigeron annuus Inhibits Protein Glycation, Aldose Reductase, and Cataractogenesis

(2010) Dae Sik Jang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum

(2010) Sri Fatmawati et al.   FITOTERAPIA

Extraction and identification of three major aldose reductase inhibitors from Artemisia montana

(2010) Hyun Ah Jung et al.   FOOD AND CHEMICAL TOXICOLOGY

Rapid isolation of geraniin from Nephelium lappaceum rind waste and its anti-hyperglycemic activity

(2010) Uma D. Palanisamy et al.   FOOD CHEMISTRY

Inhibition of Aldose ReductaseIn Vitroby Constituents ofGanoderma lucidum

(2010) Sri Fatmawati et al.   PLANTA MEDICA

Isorhamnetin-3-glucoside alleviates oxidative stress and opacification in selenite cataract in vitro

(2010) V. Gayathri Devi et al.   TOXICOLOGY IN VITRO

Investigations of anti-inflammatory, antinociceptive, antioxidant and aldose reductase inhibitory activities of phenolic compounds from Sideritis brevibracteata

(2009) Ayşegül Güvenç et al.   FOOD CHEMISTRY

Aldose reductase inhibitors fromLitchi chinensisSonn

(2009) Sung-Jae Lee et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Inhibitors of Aldose Reductase and Formation of Advanced Glycation End-Products in Moutan Cortex (Paeonia suffruticosa)

(2009) Do Thi Ha et al.   JOURNAL OF NATURAL PRODUCTS

Aldose Reductase Inhibitors from Viola hondoensis W. Becker et H Boss

(2008) Ill-Min Chung et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Constituents of the flowers of Erigeron annuus with inhibitory activity on the formation of advanced glycation end products (AGEs) and aldose reductase

(2008) Dae Sik Jang et al.   ARCHIVES OF PHARMACAL RESEARCH

Inhibitory activities of the alkaloids from Coptidis Rhizoma against aldose reductase

(2008) Hyun Ah Jung et al.   ARCHIVES OF PHARMACAL RESEARCH

Inhibitory Constituents of Aldose Reductase in the Fruiting Body of Phellinus linteus

(2008) Yeon Sil Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibitory Effect of the Compounds Isolated from Rhus verniciflua on Aldose Reductase and Advanced Glycation Endproducts

(2008) Eun Ha Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Inhibition of aldose reductase from cataracted eye lenses by finger millet (Eleusine coracana) polyphenols

(2008) S. Chethan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Bioactive Constituents from Chinese Natural Medicines. XXXII. Aminopeptidase N and Aldose Reductase Inhibitors from Sinocrassula indica: Structures of Sinocrassosides B4, B5, C1, and D1—D3

(2008) Toshio Morikawa et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Aldose-Reductase- and Protein-Glycation-Inhibitory Principles from the Whole Plant ofDuchesnea chrysantha

(2008) Jong Min Kim et al.   CHEMISTRY & BIODIVERSITY

Genistein inhibits aldose reductase activity and high glucose-induced TGF-β2 expression in human lens epithelial cells

(2008) Young Sook Kim et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Putative Anticataract Properties of Honey Studied by the Action of Flavonoids on a Lens Culture Model

(2008) Patricia Vit et al.   JOURNAL OF HEALTH SCIENCE

Inhibitory activities of prenylated flavonoids fromSophora flavescensagainst aldose reductase and generation of advanced glycation endproducts

(2008) Hyun Ah Jung et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Inhibitory effect of rhetsinine isolated from Evodia rutaecarpa on aldose reductase activity

(2007) A. Kato et al.   PHYTOMEDICINE