Regulation of in vivo dynein force production by CDK5 and 14-3-3ε and KIAA0528

Glycogen synthase kinase-3 and its inhibitors: Potential target for various therapeutic conditions

(2018) A. Prasanth Saraswati et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

CDK5-dependent activation of dynein in the axon initial segment regulates polarized cargo transport in neurons

(2017) Eva Klinman et al.   TRAFFIC

CDP138 silencing inhibits TGF-β/Smad signaling to impair radioresistance and metastasis via GDF15 in lung cancer

(2017) Yanwei Lu et al.   Cell Death & Disease

Increased identification of novel variants in type 2 diabetes, birth weight and their pleiotropic loci

(2017) Chun-Ping Zeng et al.   Journal of Diabetes

The mammalian dynein–dynactin complex is a strong opponent to kinesin in a tug-of-war competition

(2016) Vladislav Belyy et al.   NATURE CELL BIOLOGY

How Dynein Moves Along Microtubules

(2016) Gira Bhabha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Load-induced enhancement of Dynein force production by LIS1–NudE in vivo and in vitro

(2016) Babu J. N. Reddy et al.   Nature Communications

GSK-3β Phosphorylation of Cytoplasmic Dynein Reduces Ndel1 Binding to Intermediate Chains and Alters Dynein Motility

(2015) Feng J. Gao et al.   TRAFFIC

AMPK activation promotes lipid droplet dispersion on detyrosinated microtubules to increase mitochondrial fatty acid oxidation

(2015) Albert Herms et al.   Nature Communications

Stress-Induced CDK5 Activation Disrupts Axonal Transport via Lis1/Ndel1/Dynein

(2015) Eva Klinman et al.   Cell Reports

Calibration of Optical Tweezers for In Vivo Force Measurements: How do Different Approaches Compare?

(2014) Yonggun Jun et al.   BIOPHYSICAL JOURNAL

Proteomic Analysis of the Human Cyclin-dependent Kinase Family Reveals a Novel CDK5 Complex Involved in Cell Growth and Migration

(2014) Shuangbing Xu et al.   MOLECULAR & CELLULAR PROTEOMICS

An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ

(2014) Alexander S. Banks et al.   NATURE

Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport

(2014) Suvranta K. Tripathy et al.   NATURE CELL BIOLOGY

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Physiological and pathological phosphorylation of tau by Cdk5

(2014) Taeko Kimura et al.   Frontiers in Molecular Neuroscience

Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs

(2013) L. Amanda Sadacca et al.   MOLECULAR BIOLOGY OF THE CELL

Functions and mechanics of dynein motor proteins

(2013) Anthony J. Roberts et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5

(2012) Abul Arif   BIOCHEMICAL PHARMACOLOGY

Native disorder mediates binding of dynein to NudE and dynactin

(2012) Elisar Barbar   BIOCHEMICAL SOCIETY TRANSACTIONS

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

PTPN14 is required for the density-dependent control of YAP1

(2012) W. Wang et al.   GENES & DEVELOPMENT

Intrinsic Disorder in Dynein Intermediate Chain Modulates Its Interactions with NudE and Dynactin

(2012) Afua Nyarko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tug-of-War in Motor Protein Ensembles Revealed with a Programmable DNA Origami Scaffold

(2012) N. D. Derr et al.   SCIENCE

Networks of Polarized Actin Filaments in the Axon Initial Segment Provide a Mechanism for Sorting Axonal and Dendritic Proteins

(2012) Kaori Watanabe et al.   Cell Reports

C2 Domain-Containing Phosphoprotein CDP138 Regulates GLUT4 Insertion into the Plasma Membrane

(2011) Xiangyang Xie et al.   Cell Metabolism

Structural Dynamics and Multiregion Interactions in Dynein-Dynactin Recognition

(2011) Jessica L. Morgan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutually Exclusive Cytoplasmic Dynein Regulation by NudE-Lis1 and Dynactin

(2011) Richard J. McKenney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cdk5-Dependent Switch Regulates Lis1/Ndel1/Dynein-Driven Organelle Transport in Adult Axons

(2011) J. P. Pandey et al.   JOURNAL OF NEUROSCIENCE

Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport

(2011) A. Kunwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclin-Dependent Kinase 5/p35/p39: A Novel and Imminent Therapeutic Target for Diabetes Mellitus

(2011) Danish Ahmed et al.   International Journal of Endocrinology

LIS1 and NudE Induce a Persistent Dynein Force-Producing State

(2010) Richard J. McKenney et al.   CELL

Motor Coordination via a Tug-of-War Mechanism Drives Bidirectional Vesicle Transport

(2010) Adam G. Hendricks et al.   CURRENT BIOLOGY

The atypical kinase Cdk5 is activated by insulin, regulates the association between GLUT4 and E-Syt1, and modulates glucose transport in 3T3-L1 adipocytes

(2009) V. Lalioti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes

(2009) V. Soppina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crosstalk between Cdk5 and GSK3β: Implications for Alzheimer's Disease

(2009) Olivia Engmann   Frontiers in Molecular Neuroscience

Neuronal migration disorders: clinical, neuroradiologic and genetics aspects

(2008) Alberto Spalice et al.   ACTA PAEDIATRICA

Consequences of Motor Copy Number on the Intracellular Transport of Kinesin-1-Driven Lipid Droplets

(2008) George T. Shubeita et al.   CELL

Lis1 and Ndel1 influence the timing of nuclear envelope breakdown in neural stem cells

(2008) Sachin Hebbar et al.   JOURNAL OF CELL BIOLOGY