Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Machine learning and structural analysis of Mycobacterium tuberculosis pan-genome identifies genetic signatures of antibiotic resistance
Authors
Keywords
-
Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-10-11
DOI
10.1038/s41467-018-06634-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ssbio: a Python framework for structural systems biology
- (2018) Nathan Mih et al. BIOINFORMATICS
- Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions
- (2018) Erol S. Kavvas et al. BMC Systems Biology
- Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
- (2017) Abigail L Manson et al. NATURE GENETICS
- Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation inMycobacterium tuberculosis
- (2017) Susan Puckett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- dfrA thyADouble Deletion inpara-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains
- (2016) Danesh Moradigaravand et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance
- (2016) Christopher A Desjardins et al. NATURE GENETICS
- Microbial genome-wide association studies: lessons from human GWAS
- (2016) Robert A. Power et al. NATURE REVIEWS GENETICS
- UniProt: the universal protein knowledgebase
- (2016) NUCLEIC ACIDS RESEARCH
- Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees
- (2016) Ivica Letunic et al. NUCLEIC ACIDS RESEARCH
- Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis
- (2016) Pooja Gopal et al. ACS Infectious Diseases
- Identifying lineage effects when controlling for population structure improves power in bacterial association studies
- (2016) Sarah G. Earle et al. Nature Microbiology
- Molecular Analysis of theembCABLocus andembRGene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France
- (2015) Florence Brossier et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- The advent of genome-wide association studies for bacteria
- (2015) Peter E Chen et al. CURRENT OPINION IN MICROBIOLOGY
- Study of efflux pump gene expression in rifampicin-monoresistant Mycobacterium tuberculosis clinical isolates
- (2015) Guilian Li et al. JOURNAL OF ANTIBIOTICS
- Genome sequencing reveals novel deletions associated with secondary resistance to pyrazinamide in MDRMycobacterium tuberculosis
- (2015) Elena Martinez et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance: a retrospective cohort study
- (2015) Timothy M Walker et al. LANCET INFECTIOUS DISEASES
- The I-TASSER Suite: protein structure and function prediction
- (2015) Jianyi Yang et al. NATURE METHODS
- Novel katG mutations causing isoniazid resistance in clinical M. tuberculosis isolates
- (2015) Jessica N Torres et al. Emerging Microbes & Infections
- RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies
- (2014) Alexandros Stamatakis BIOINFORMATICS
- Equitability, mutual information, and the maximal information coefficient
- (2014) Justin B. Kinney et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A robust SNP barcode for typing Mycobacterium tuberculosis complex strains
- (2014) Francesc Coll et al. Nature Communications
- Isocitrate lyase mediates broad antibiotic tolerance in Mycobacterium tuberculosis
- (2014) Madhumitha Nandakumar et al. Nature Communications
- para-Aminosalicylic Acid Is a Prodrug Targeting Dihydrofolate Reductase inMycobacterium tuberculosis
- (2013) Jun Zheng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis
- (2013) Maha R Farhat et al. NATURE GENETICS
- Evolution of high-level ethambutol-resistant tuberculosis through interacting mutations in decaprenylphosphoryl-β-D-arabinose biosynthetic and utilization pathway genes
- (2013) Hassan Safi et al. NATURE GENETICS
- PATRIC, the bacterial bioinformatics database and analysis resource
- (2013) Alice R. Wattam et al. NUCLEIC ACIDS RESEARCH
- Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
- (2013) F. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Putative Compensatory Mutations in the rpoC Gene of Rifampin-Resistant Mycobacterium tuberculosis Are Associated with Ongoing Transmission
- (2012) M. de Vos et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Upregulation of the Phthiocerol Dimycocerosate Biosynthetic Pathway by Rifampin-Resistant,rpoBMutant Mycobacterium tuberculosis
- (2012) Gregory P. Bisson et al. JOURNAL OF BACTERIOLOGY
- Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin-resistantMycobacterium tuberculosisthrough Efflux
- (2011) Gail E. Louw et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Mutations ingidBConfer Low-Level Streptomycin Resistance in Mycobacterium tuberculosis
- (2011) Sharon Y. Wong et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Alarming levels of drug-resistant tuberculosis in Belarus: results of a survey in Minsk
- (2011) Alena Skrahina et al. EUROPEAN RESPIRATORY JOURNAL
- Mycobacterium tuberculosis thymidylate synthase gene thyX is essential and potentially bifunctional, while thyA deletion confers resistance to p-aminosalicylic acid
- (2011) A. S. Fivian-Hughes et al. MICROBIOLOGY-SGM
- 13C Metabolic Flux Analysis Identifies an Unusual Route for Pyruvate Dissimilation in Mycobacteria which Requires Isocitrate Lyase and Carbon Dioxide Fixation
- (2011) Dany J. V. Beste et al. PLoS Pathogens
- New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli
- (2010) Tobias Werther et al. FEBS Journal
- Fluoroquinolone Resistance in Mycobacterium tuberculosis and Mutations in gyrA and gyrB
- (2009) A. Von Groll et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Identification of a Novel Multidrug Efflux Pump of Mycobacterium tuberculosis
- (2008) O. Danilchanka et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mycothiol biosynthesis is essential for ethionamide susceptibility inMycobacterium tuberculosis
- (2008) Catherine Vilchèze et al. MOLECULAR MICROBIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search