Novel katG mutations causing isoniazid resistance in clinical M. tuberculosis isolates

Phenotypic and genotypic diversity in a multinational sample of drug-resistant Mycobacterium tuberculosis isolates

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Detection of novel and reported mutations in the rpoB, katG and inhA genes in multidrug-resistant tuberculosis isolates: A hospital-based study

(2015) Gayathri Ramasubban et al.   Journal of Global Antimicrobial Resistance

Evaluation of Pyrosequencing for Detecting Extensively Drug-Resistant Mycobacterium tuberculosis among Clinical Isolates from Four High-Burden Countries

(2014) Kanchan Ajbani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Global Consortium for Drug-resistant Tuberculosis Diagnostics (GCDD): design of a multi-site, head-to-head study of three rapid tests to detect extensively drug-resistant tuberculosis

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PredictingMycobacterium tuberculosisComplex Clades Using Knowledge-Based Bayesian Networks

(2014) Minoo Aminian et al.   Biomed Research International

The impact of drug resistance on Mycobacterium tuberculosis physiology: what can we learn from rifampicin?

(2014) Anastasia Koch et al.   Emerging Microbes & Infections

Predicting Extensively Drug-Resistant Mycobacterium tuberculosis Phenotypes with Genetic Mutations

(2013) T. C. Rodwell et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Pyrosequencing for Rapid Detection of Extensively Drug-Resistant Mycobacterium tuberculosis in Clinical Isolates and Clinical Specimens

(2013) S.- Y. G. Lin et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Predictive Value of Molecular Drug Resistance Testing of Mycobacterium tuberculosis Isolates in Valle del Cauca, Colombia

(2013) B. E. Ferro et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A silent mutation inmabAconfers isoniazid resistance onMycobacterium tuberculosis

(2013) Hiroki Ando et al.   MOLECULAR MICROBIOLOGY

The mycobacterial antibiotic resistance determinant WhiB7 acts as a transcriptional activator by binding the primary sigma factor SigA (RpoV)

(2013) Ján Burian et al.   NUCLEIC ACIDS RESEARCH

Effect of Mutation and Genetic Background on Drug Resistance in Mycobacterium tuberculosis

(2012) Lukas Fenner et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

TB-Lineage: An online tool for classification and analysis of strains of Mycobacterium tuberculosis complex

(2012) Amina Shabbeer et al.   INFECTION GENETICS AND EVOLUTION

Use of a Molecular Diagnostic Test in AFB Smear Positive Tuberculosis Suspects Greatly Reduces Time to Detection of Multidrug Resistant Tuberculosis

(2012) Nestani Tukvadze et al.   PLoS One

Precise Null Deletion Mutations of the Mycothiol Synthesis Genes Reveal Their Role in Isoniazid and Ethionamide Resistance in Mycobacterium smegmatis

(2011) Xia Xu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

BamTools: a C++ API and toolkit for analyzing and managing BAM files

(2011) D. W. Barnett et al.   BIOINFORMATICS

Treatment Outcomes of Isoniazid-Resistant Tuberculosis Patients, Western Cape Province, South Africa

(2011) K. R. Jacobson et al.   CLINICAL INFECTIOUS DISEASES

Pyrosequencing for Rapid Molecular Detection of Rifampin and Isoniazid Resistance in Mycobacterium tuberculosis Strains and Clinical Specimens

(2011) N. Garcia-Sierra et al.   JOURNAL OF CLINICAL MICROBIOLOGY

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Identification of katG Mutations Associated with High-Level Isoniazid Resistance in Mycobacterium tuberculosis

(2010) H. Ando et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis

(2010) Dmitri Shcherbakov et al.   MOLECULAR MICROBIOLOGY

Rapid Molecular Detection of Tuberculosis and Rifampin Resistance

(2010) Catharina C. Boehme et al.   NEW ENGLAND JOURNAL OF MEDICINE

VarScan: variant detection in massively parallel sequencing of individual and pooled samples

(2009) Daniel C. Koboldt et al.   BIOINFORMATICS

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Simple and efficient site-directed mutagenesis using two single-primer reactions in parallel to generate mutants for protein structure-function studies

(2009) Oded Edelheit et al.   BMC BIOTECHNOLOGY

Clinical Efficacy of Direct DNA Sequencing Analysis on Sputum Specimens for Early Detection of Drug-Resistant Mycobacterium tuberculosis in a Clinical Setting

(2009) Jeong-Hee Choi et al.   CHEST