Optogenetic dissection of Rac1 and Cdc42 gradient shaping

Cells lay their own tracks – optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration

(2017) Seth P. Zimmerman et al.   JOURNAL OF CELL SCIENCE

Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement

(2017) Peter J. M. van Haastert et al.   MOLECULAR BIOLOGY OF THE CELL

Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling

(2016) Ludovico Fusco et al.   JOURNAL OF CELL BIOLOGY

FRET binding antenna reports spatiotemporal dynamics of GDI–Cdc42 GTPase interactions

(2016) Louis Hodgson et al.   Nature Chemical Biology

Predictive Spatiotemporal Manipulation of Signaling Perturbations Using Optogenetics

(2015) Leo Valon et al.   BIOPHYSICAL JOURNAL

Actin Flows Mediate a Universal Coupling between Cell Speed and Cell Persistence

(2015) Paolo Maiuri et al.   CELL

Locally excitable Cdc42 signals steer cells during chemotaxis

(2015) Hee Won Yang et al.   NATURE CELL BIOLOGY

Distinct predictive performance of Rac1 and Cdc42 in cell migration

(2015) Masataka Yamao et al.   Scientific Reports

A New Genetically Encoded Single-Chain Biosensor for Cdc42 Based on FRET, Useful for Live-Cell Imaging

(2014) Samer Hanna et al.   PLoS One

The Rac-FRET Mouse Reveals Tight Spatiotemporal Control of Rac Activity in Primary Cells and Tissues

(2014) Anna-Karin E. Johnsson et al.   Cell Reports

Triggering Cell Adhesion, Migration or Shape Change with a Dynamic Surface Coating

(2013) Stijn F. M. van Dongen et al.   ADVANCED MATERIALS

Gradient sensing during chemotaxis

(2013) Tian Jin   CURRENT OPINION IN CELL BIOLOGY

Inhibitory signalling to the Arp2/3 complex steers cell migration

(2013) Irene Dang et al.   NATURE

An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration

(2013) Chuan-Hsiang Huang et al.   NATURE CELL BIOLOGY

Optical control demonstrates switch-like PIP3 dynamics underlying the initiation of immune cell migration

(2013) W. K. A. Karunarathne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chordin forms a self-organizing morphogen gradient in the extracellular space between ectoderm and mesoderm in the Xenopus embryo

(2013) J.-L. Plouhinec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients

(2013) M. Weber et al.   SCIENCE

Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol

(2013) Alvaro Gutierrez-Uzquiza et al.   Nature Communications

Amplification and Temporal Filtering during Gradient Sensing by Nerve Growth Cones Probed with a Microfluidic Assay

(2012) Mathieu Morel et al.   BIOPHYSICAL JOURNAL

The first World Cell Race

(2012) Paolo Maiuri et al.   CURRENT BIOLOGY

Parallel and patterned optogenetic manipulation of neurons in the brain slice using a DMD-based projector

(2012) Seiichiro Sakai et al.   NEUROSCIENCE RESEARCH

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front–back polarity in migrating cells

(2011) Miguel Vicente-Manzanares et al.   JOURNAL OF CELL BIOLOGY

A pharmacological cocktail for arresting actin dynamics in living cells

(2011) Grace E. Peng et al.   MOLECULAR BIOLOGY OF THE CELL

SH3BP1, an Exocyst-Associated RhoGAP, Inactivates Rac1 at the Front to Drive Cell Motility

(2011) Maria Carla Parrini et al.   MOLECULAR CELL

Bright and stable near-infrared fluorescent protein for in vivo imaging

(2011) Grigory S Filonov et al.   NATURE BIOTECHNOLOGY

Rho protein crosstalk: another social network?

(2011) Christophe Guilluy et al.   TRENDS IN CELL BIOLOGY

I-BAR domain proteins: linking actin and plasma membrane dynamics

(2010) Hongxia Zhao et al.   CURRENT OPINION IN CELL BIOLOGY

Modelling the Bicoid gradient

(2010) O. Grimm et al.   DEVELOPMENT

The Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck

(2010) J. V. Abella et al.   JOURNAL OF CELL SCIENCE

Spatio-temporal Rho GTPase signaling - where are we now?

(2010) O. Pertz   JOURNAL OF CELL SCIENCE

Rapid blue-light–mediated induction of protein interactions in living cells

(2010) Matthew J Kennedy et al.   NATURE METHODS

Simple and rapid process for single cell micro-patterning

(2009) Ammar Azioune et al.   LAB ON A CHIP

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Scaling of the BMP activation gradient in Xenopus embryos

(2008) Danny Ben-Zvi et al.   NATURE