Epithelial cells release adenosine to promote local TNF production in response to polarity disruption

The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition

(2017) Masatoshi Yamamoto et al.   NATURE

Feedback amplification loop drives malignant growth in epithelial tissues

(2017) Mariana Muzzopappa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of adipokinetic hormone and adenosine in the anti-stress response in Drosophila melanogaster

(2016) Milada Zemanová et al.   JOURNAL OF INSECT PHYSIOLOGY

Survival of the Fittest: Essential Roles of Cell Competition in Development, Aging, and Cancer

(2016) Marisa M. Merino et al.   TRENDS IN CELL BIOLOGY

Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?

(2016) Pier Andrea Borea et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cell Signaling and Stress Responses

(2016) Gökhan S. Hotamisligil et al.   Cold Spring Harbor Perspectives in Biology

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth

(2015) Ditte S. Andersen et al.   NATURE

Extracellular Adenosine Mediates a Systemic Metabolic Switch during Immune Response

(2015) Adam Bajgar et al.   PLOS BIOLOGY

TNF and TNF-receptors: From mediators of cell death and inflammation to therapeutic giants – past, present and future

(2014) Lisa M. Sedger et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Mitochondria Are Gate-keepers of T Cell Function by Producing the ATP That Drives Purinergic Signaling

(2014) Carola Ledderose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutation in the Drosophila melanogaster adenosine receptor gene selectively decreases the mosaic hyperplastic epithelial outgrowth rates in wts or dco heterozygous flies

(2014) Roman Sidorov et al.   Purinergic Signalling

JNK signalling in cancer: in need of new, smarter therapeutic targets

(2013) Concetta Bubici et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Versatile ΦC31 Based Reporter System for Measuring AP-1 and Nrf2 Signaling in Drosophila and in Tissue Culture

(2012) Nirmalya Chatterjee et al.   PLoS One

Interaction between Differentiating Cell- and Niche-Derived Signals in Hematopoietic Progenitor Maintenance

(2011) Bama Charan Mondal et al.   CELL

Apical deficiency triggers JNK-dependent apoptosis in the embryonic epidermis of Drosophila

(2011) G. Kolahgar et al.   DEVELOPMENT

Elimination of Oncogenic Neighbors by JNK-Mediated Engulfment in Drosophila

(2011) Shizue Ohsawa et al.   DEVELOPMENTAL CELL

Swatting flies: modelling wound healing and inflammation in Drosophila

(2011) W. Razzell et al.   Disease Models & Mechanisms

Adenosine receptors and cancer

(2010) Stefania Gessi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Increased extracellular adenosine in Drosophila that are deficient in adenosine deaminase activates a release of energy stores leading to wasting and death

(2010) M. Zuberova et al.   Disease Models & Mechanisms

Equilibrative Nucleoside Transporter 2 Regulates Associative Learning and Synaptic Function in Drosophila

(2010) D. Knight et al.   JOURNAL OF NEUROSCIENCE

Tissue Damage-Induced Intestinal Stem Cell Division in Drosophila

(2009) Alla Amcheslavsky et al.   Cell Stem Cell

Intrinsic Tumor Suppression and Epithelial Maintenance by Endocytic Activation of Eiger/TNF Signaling in Drosophila

(2009) Tatsushi Igaki et al.   DEVELOPMENTAL CELL

The Effects of Caffeine on Sleep in Drosophila Require PKA Activity, But Not the Adenosine Receptor

(2009) M. N. Wu et al.   JOURNAL OF NEUROSCIENCE

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

Adenosine receptors: therapeutic aspects for inflammatory and immune diseases

(2008) György Haskó et al.   NATURE REVIEWS DRUG DISCOVERY

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

(2008) L E Dow et al.   ONCOGENE