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Emerging Roles of Non-Coding RNA Transcription

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MiR-101-3p Regulates the Viability of Lung Squamous Carcinoma Cells via Targeting EZH2

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PTENP1 inhibits the growth of esophageal squamous cell carcinoma by regulating SOCS6 expression and correlates with disease prognosis

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A functional pseudogene,NMRAL2P, is regulated by Nrf2 and serves as a coactivator ofNQO1in sulforaphane-treated colon cancer cells

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dreamBase: DNA modification, RNA regulation and protein binding of expressed pseudogenes in human health and disease

(2017) Ling-Ling Zheng et al.   NUCLEIC ACIDS RESEARCH

miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions

(2017) Chih-Hung Chou et al.   NUCLEIC ACIDS RESEARCH

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

MiRNA199a-3p suppresses tumor growth, migration, invasion and angiogenesis in hepatocellular carcinoma by targeting VEGFA, VEGFR1, VEGFR2, HGF and MMP2

(2017) Alip Ghosh et al.   Cell Death & Disease

The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism

(2017) Marco De Martino et al.   Genes

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

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miR-361-5p inhibits hepatocellular carcinoma cell proliferation and invasion by targeting VEGFA

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Pseudogene PTENP1 functions as a competing endogenous RNA (ceRNA) to regulate PTEN expression by sponging miR-499-5p

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Upregulation of SNHG6 regulates ZEB1 expression by competitively binding miR-101-3p and interacting with UPF1 in hepatocellular carcinoma

(2016) Lei Chang et al.   CANCER LETTERS

PTENp1, a natural sponge of miR-21, mediates PTEN expression to inhibit the proliferation of oral squamous cell carcinoma

(2016) Ling Gao et al.   MOLECULAR CARCINOGENESIS

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

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Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches

(2016) Julia Beermann et al.   PHYSIOLOGICAL REVIEWS

mir-101-3p is a key regulator of tumor metabolism in triple negative breast cancer targeting AMPK

(2016) Peng Liu et al.   Oncotarget

HMGA1P7-pseudogene regulates H19 and Igf2 expression by a competitive endogenous RNA mechanism

(2016) Marco De Martino et al.   Scientific Reports

Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation

(2015) Chiu-Ling Chen et al.   BIOMATERIALS

Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway

(2015) Alexandra Drakaki et al.   BMC CANCER

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAs

(2015) Francesco Esposito et al.   Oncotarget

PI3K/AKT signaling pathway and cancer: an updated review

(2014) Miriam Martini et al.   ANNALS OF MEDICINE

MicroRNA-200b targets protein kinase Cα and suppresses triple-negative breast cancer metastasis

(2014) Brock Humphries et al.   CARCINOGENESIS

HMGA1-pseudogene overexpression contributes to cancer progression

(2014) Francesco Esposito et al.   CELL CYCLE

Sorafenib Blocks the HIF-1α/VEGFA Pathway, Inhibits Tumor Invasion, and Induces Apoptosis in Hepatoma Cells

(2014) Ming Xu et al.   DNA AND CELL BIOLOGY

FOXO1 3′UTR functions as a ceRNA in repressing the metastases of breast cancer cells via regulating miRNA activity

(2014) Jue Yang et al.   FEBS LETTERS

The multilayered complexity of ceRNA crosstalk and competition

(2014) Yvonne Tay et al.   NATURE

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

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starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

microRNA-9 Suppresses the Proliferation, Invasion and Metastasis of Gastric Cancer Cells through Targeting Cyclin D1 and Ets1

(2013) Liduan Zheng et al.   PLoS One

Tumour angiogenesis regulation by the miR-200 family

(2013) Chad V. Pecot et al.   Nature Communications

Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients

(2012) Balázs Győrffy et al.   ENDOCRINE-RELATED CANCER

An integrated encyclopedia of DNA elements in the human genome

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Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis

(2012) E Louie et al.   ONCOGENE

Pseudogenes are not pseudo any more

(2012) Yan-Zi Wen et al.   RNA Biology

Pseudogenes: Newly Discovered Players in Human Cancer

(2012) L. Poliseno   Science Signaling

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

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MicroRNA-200b reverses chemoresistance of docetaxel-resistant human lung adenocarcinoma cells by targeting E2F3

(2011) Bing Feng et al.   CANCER

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Pseudogenes: Pseudo-functional or key regulators in health and disease?

(2011) R. C. Pink et al.   RNA

Down-Regulation of a Host MicroRNA by a Herpesvirus saimiri Noncoding RNA

(2010) D. Cazalla et al.   SCIENCE

Analyzing biological network parameters with CentiScaPe

(2009) Giovanni Scardoni et al.   BIOINFORMATICS

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-κB1

(2009) Li-Min Guo et al.   FEBS Journal

Genomics: Protein fossils live on as RNA

(2008) Rajkumar Sasidharan et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY