Blockade of CTLA-4 and Tim-3 pathways induces fetal loss with altered cytokine profiles by decidual CD4+T cells

Next generation of immune checkpoint therapy in cancer: new developments and challenges

(2018) Julian A. Marin-Acevedo et al.   Journal of Hematology & Oncology

Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas

(2017) Guoying Zhou et al.   GASTROENTEROLOGY

Immuno-Oncology in Hepatocellular Carcinoma: 2017 Update

(2017) Masatoshi Kudo   ONCOLOGY

Distinct Transcriptional and Alternative Splicing Signatures of Decidual CD4+ T Cells in Early Human Pregnancy

(2017) Weihong Zeng et al.   Frontiers in Immunology

Programmed cell death-1 (PD-1) and T-cell immunoglobulin mucin-3 (Tim-3) regulate CD4+T cells to induce Type 2 helper T cell (Th2) bias at the maternal–fetal interface

(2016) SongCun Wang et al.   HUMAN REPRODUCTION

Human HLA-G+ extravillous trophoblasts: Immune-activating cells that interact with decidual leukocytes

(2015) Tamara Tilburgs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal CD4+T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission

(2015) Kristy M. Bialas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The immunology of pregnancy: Regulatory T cells control maternal immune tolerance toward the fetus

(2014) Claudia La Rocca et al.   IMMUNOLOGY LETTERS

Cutting Edge: Committed Th1 CD4+ T Cell Differentiation Blocks Pregnancy-Induced Foxp3 Expression with Antigen-Specific Fetal Loss

(2014) L. Xin et al.   JOURNAL OF IMMUNOLOGY

Adoptive Transfer of Treg Cells Counters Adverse Effects of Toxoplasma gondii Infection on Pregnancy

(2014) Y. Liu et al.   JOURNAL OF INFECTIOUS DISEASES

Fetomaternal immune cross-talk and its consequences for maternal and offspring's health

(2013) Petra C Arck et al.   NATURE MEDICINE

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Anti-TIM3 Antibody Promotes T Cell IFN- -Mediated Antitumor Immunity and Suppresses Established Tumors

(2011) S. F. Ngiow et al.   CANCER RESEARCH

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation

(2011) Wei Liao et al.   CURRENT OPINION IN IMMUNOLOGY

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Th1/Th2/Th17 and Regulatory T-Cell Paradigm in Pregnancy

(2010) Shigeru Saito et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity

(2010) Rachel H. McMahan et al.   JOURNAL OF CLINICAL INVESTIGATION

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Association of HIV-Specific and Total CD8+ T Memory Phenotypes in Subtype C HIV-1 Infection with Viral Set Point

(2009) W. A. Burgers et al.   JOURNAL OF IMMUNOLOGY

Fetal–maternal HLA-C mismatch is associated with decidual T cell activation and induction of functional T regulatory cells

(2009) Tamara Tilburgs et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY