NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies

Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes

(2018) M. Giuliani et al.   Scientific Reports

Influence of protein fold stability on immunogenicity and its implications for vaccine design

(2017) Sandra Scheiblhofer et al.   Expert Review of Vaccines

Emerging experience with meningococcal serogroup B protein vaccines

(2017) Daniela Toneatto et al.   Expert Review of Vaccines

Exploiting chimeric human antibodies to characterize a protective epitope of Neisseria adhesin A, one of the Bexsero vaccine components

(2016) Isabella Bertoldi et al.   FASEB JOURNAL

4CMenB vaccine effectiveness: reasons for optimism

(2016) Nicole E Basta et al.   LANCET

Effectiveness and impact of a reduced infant schedule of 4CMenB vaccine against group B meningococcal disease in England: a national observational cohort study

(2016) Sydel R Parikh et al.   LANCET

Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA

(2016) Alessia Liguori et al.   PLoS Pathogens

Exploring host-pathogen interactions through genome wide protein microarray analysis

(2016) Luigi Scietti et al.   Scientific Reports

New findings on the function and potential applications of the trimeric autotransporter adhesin

(2015) Wanhai Qin et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Neisseria Adhesin A Variation and Revised Nomenclature Scheme

(2014) Stefania Bambini et al.   Clinical and Vaccine Immunology

Proof of principle for epitope-focused vaccine design

(2014) Bruno E. Correia et al.   NATURE

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Role of ARF6, Rab11 and External Hsp90 in the Trafficking and Recycling of Recombinant-Soluble Neisseria meningitidis Adhesin A (rNadA) in Human Epithelial Cells

(2014) Giuseppe Bozza et al.   PLoS One

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

(2014) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assessment of fully automated antibody homology modeling protocols in molecular operating environment

(2014) Johannes K. X. Maier et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A Multi-Component Meningococcal Serogroup B Vaccine (4CMenB): The Clinical Development Program

(2013) Miguel O’Ryan et al.   DRUGS

Transcriptional Regulation of thenadAGene in Neisseria meningitidis Impacts the Prediction of Coverage of a Multicomponent Meningococcal Serogroup B Vaccine

(2012) Luca Fagnocchi et al.   INFECTION AND IMMUNITY

Toward a Meningitis-Free World

(2012) S. Black et al.   Science Translational Medicine

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens

(2012) Davide Serruto et al.   VACCINE

Meningococcal disease: Clinical presentation and sequelae

(2012) David Pace et al.   VACCINE

The changing epidemiology of meningococcal disease in North America 1945–2010

(2012) Carmen Baccarini et al.   Human Vaccines & Immunotherapeutics

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

BIGSdb: Scalable analysis of bacterial genome variation at the population level

(2011) Keith A Jolley et al.   BMC BIOINFORMATICS

Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

(2011) Paolo Montanari et al.   CELLULAR MICROBIOLOGY

In the NadR Regulon, Adhesins and Diverse Meningococcal Functions Are Regulated in Response to Signals in Human Saliva

(2011) L. Fagnocchi et al.   JOURNAL OF BACTERIOLOGY

The Soluble Recombinant Neisseria meningitidis Adhesin NadAΔ351–405 Stimulates Human Monocytes by Binding to Extracellular Hsp90

(2011) Paola Cecchini et al.   PLoS One

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Multicenter, Open‐Label, Randomized Phase II Controlled Trial of an Investigational Recombinant Meningococcal Serogroup B Vaccine With and Without Outer Membrane Vesicles, Administered in Infancy

(2010) Jamie Findlow et al.   CLINICAL INFECTIOUS DISEASES

Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted  -Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions

(2010) R. Tavano et al.   JOURNAL OF BACTERIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Global epidemiology of meningococcal disease

(2009) Lee H. Harrison et al.   VACCINE

Structural organization of NadAΔ351–405, a recombinant MenB vaccine component, by its physico-chemical characterization at drug substance level

(2009) Claudia Magagnoli et al.   VACCINE

Human monocytes/macrophages are a target of Neisseria meningitidis Adhesin A (NadA)

(2008) Susanna Franzoso et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Combining the polymerase incomplete primer extension method for cloning and mutagenesis with microscreening to accelerate structural genomics efforts

(2007) Heath E. Klock et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS