New findings on the function and potential applications of the trimeric autotransporter adhesin

Haemophilus influenzae surface fibril (Hsf) is a unique twisted hairpin-like trimeric autotransporter

(2015) Birendra Singh et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Differential gene expression profiling of Actinobacillus pleuropneumoniae during induction of primary alveolar macrophage apoptosis in piglets

(2015) Lei Wang et al.   MICROBIAL PATHOGENESIS

The Adh adhesin domain is required for trimeric autotransporter Apa1-mediated Actinobacillus pleuropneumoniae adhesion, autoaggregation, biofilm formation and pathogenicity

(2015) Lei Wang et al.   VETERINARY MICROBIOLOGY

A Fine-Tuned Interaction between Trimeric Autotransporter Haemophilus Surface Fibrils and Vitronectin Leads to Serum Resistance and Adherence to Respiratory Epithelial Cells

(2014) B. Singh et al.   INFECTION AND IMMUNITY

Evolutionary Conservation in Biogenesis of β-Barrel Proteins Allows Mitochondria to Assemble a Functional Bacterial Trimeric Autotransporter Protein

(2014) Thomas Ulrich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An autotransporter display platform for the development of multivalent recombinant bacterial vector vaccines

(2014) Wouter SP Jong et al.   Microbial Cell Factories

Autodisplay for the co-expression of lipase and foldase on the surface of E. coli: washing with designer bugs

(2014) Eva Kranen et al.   Microbial Cell Factories

Role of ARF6, Rab11 and External Hsp90 in the Trafficking and Recycling of Recombinant-Soluble Neisseria meningitidis Adhesin A (rNadA) in Human Epithelial Cells

(2014) Giuseppe Bozza et al.   PLoS One

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

(2014) Enrico Malito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Haemophilus ducreyi trimeric autotransporter adhesin DsrA protects against an experimental infection in the swine model of chancroid

(2014) William G. Fusco et al.   VACCINE

The haemagglutinin of Avibacterium paragallinarum is a trimeric autotransporter adhesin that confers haemagglutination, cell adherence and biofilm formation activities

(2014) Yi-Ping Wang et al.   VETERINARY MICROBIOLOGY

Application of the adhesive bacterionanofiber AtaA to a novel microbial immobilization method for the production of indigo as a model chemical

(2013) Masahito Ishikawa et al.   BIOTECHNOLOGY AND BIOENGINEERING

Yersinia pseudotuberculosisuses Ail and YadA to circumvent neutrophils by directing Yop translocation during lung infection

(2013) Michelle K. Paczosa et al.   CELLULAR MICROBIOLOGY

A Trimeric Lipoprotein Assists in Trimeric Autotransporter Biogenesis in Enterobacteria

(2013) Iwan Grin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Single-molecule atomic force microscopy unravels the binding mechanism of aBurkholderia cenocepaciatrimeric autotransporter adhesin

(2013) Sofiane El-Kirat-Chatel et al.   MOLECULAR MICROBIOLOGY

Molecular Characterization of the EhaG and UpaG Trimeric Autotransporter Proteins from Pathogenic Escherichia coli

(2012) Makrina Totsika et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bartonella henselaetrimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system

(2012) Yun-Yueh Lu et al.   CELLULAR MICROBIOLOGY

O-Polysaccharide Glycosylation Is Required for Stability and Function of the Collagen Adhesin EmaA of Aggregatibacter actinomycetemcomitans

(2012) Gaoyan Tang et al.   INFECTION AND IMMUNITY

Transcriptional Regulation of thenadAGene in Neisseria meningitidis Impacts the Prediction of Coverage of a Multicomponent Meningococcal Serogroup B Vaccine

(2012) Luca Fagnocchi et al.   INFECTION AND IMMUNITY

Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteria

(2012) M. D. Hartmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assignment and secondary structure of the YadA membrane protein by solid-state MAS NMR

(2012) Shakeel A. Shahid et al.   Scientific Reports

Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

(2011) Paolo Montanari et al.   CELLULAR MICROBIOLOGY

Analysis of the BadA stalk from Bartonella henselae reveals domain-specific and domain-overlapping functions in the host cell infection process

(2011) Patrick O. Kaiser et al.   CELLULAR MICROBIOLOGY

SadA, a Trimeric Autotransporter from Salmonella enterica Serovar Typhimurium, Can Promote Biofilm Formation and Provides Limited Protection against Infection

(2011) Dhaarini Raghunathan et al.   INFECTION AND IMMUNITY

A Naturally Occurring Single-Residue Mutation in the Translocator Domain of Neisseria meningitidis NhhA Affects Trimerization, Surface Localization, and Adhesive Capabilities

(2011) Hebert Echenique-Rivera et al.   INFECTION AND IMMUNITY

Trimeric Autotransporter Adhesin-Dependent Adherence of Bartonella henselae, Bartonella quintana, and Yersinia enterocolitica to Matrix Components and Endothelial Cells under Static and Dynamic Flow Conditions

(2011) Niklas F. Müller et al.   INFECTION AND IMMUNITY

The Extended Signal Peptide of the Trimeric Autotransporter EmaA of Aggregatibacter actinomycetemcomitans Modulates Secretion

(2011) X. Jiang et al.   JOURNAL OF BACTERIOLOGY

Apa is a trimeric autotransporter adhesin ofActinobacillus pleuropneumoniaeresponsible for autoagglutination and host cell adherence

(2011) Longwen Xiao et al.   JOURNAL OF BASIC MICROBIOLOGY

The Soluble Recombinant Neisseria meningitidis Adhesin NadAΔ351–405 Stimulates Human Monocytes by Binding to Extracellular Hsp90

(2011) Paola Cecchini et al.   PLoS One

Correlation of in situ mechanosensitive responses of the Moraxella catarrhalis adhesin UspA1 with fibronectin and receptor CEACAM1 binding

(2011) C. Agnew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of E. coli IgG-Binding Protein D Suggests a General Model for Bending and Binding in Trimeric Autotransporter Adhesins

(2011) Jack C. Leo et al.   STRUCTURE

Trimeric autotransporter adhesins in members of the Burkholderia cepacia complex: a multifunctional family of proteins implicated in virulence

(2011) Dalila Mil-Homens   Frontiers in Cellular and Infection Microbiology

Structure and function of the Haemophilus influenzae autotransporters

(2011) Nicole Spahich   Frontiers in Cellular and Infection Microbiology

Trimer Stability of YadA Is Critical for Virulence of Yersinia enterocolitica

(2010) M. Schutz et al.   INFECTION AND IMMUNITY

Adhesive Activity of the Haemophilus Cryptic Genospecies Cha Autotransporter Is Modulated by Variation in Tandem Peptide Repeats

(2010) A. J. Sheets et al.   JOURNAL OF BACTERIOLOGY

Mapping of the Neisseria meningitidis NadA Cell-Binding Site: Relevance of Predicted  -Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions

(2010) R. Tavano et al.   JOURNAL OF BACTERIOLOGY

A transition from strong right-handed to canonical left-handed supercoiling in a conserved coiled-coil segment of trimeric autotransporter adhesins

(2010) Birte Hernandez Alvarez et al.   JOURNAL OF STRUCTURAL BIOLOGY

C-terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA

(2010) U. Lehr et al.   MOLECULAR MICROBIOLOGY

Structure of a Burkholderia pseudomallei Trimeric Autotransporter Adhesin Head

(2010) Thomas E. Edwards et al.   PLoS One

Secretion of a bacterial virulence factor is driven by the folding of a C-terminal segment

(2010) Janine H. Peterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HadA is an atypical new multifunctional trimeric coiled-coil adhesin ofHaemophilus influenzaebiogroupaegyptius, which promotes entry into host cells

(2009) Davide Serruto et al.   CELLULAR MICROBIOLOGY

Analysis of a collagen-binding trimeric autotransporter adhesin fromMannheimia haemolyticaA1

(2009) Michelle C. Daigneault et al.   FEMS MICROBIOLOGY LETTERS

Structural Basis for the Differential Binding Affinities of the HsfBD1 and HsfBD2 Domains in the Haemophilus influenzae Hsf Adhesin

(2009) J. N. Radin et al.   JOURNAL OF BACTERIOLOGY

Vectorial transport and folding of an autotransporter virulence protein during outer membrane secretion

(2009) Mirco Junker et al.   MOLECULAR MICROBIOLOGY

A coiled-coil motif that sequesters ions to the hydrophobic core

(2009) M. D. Hartmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Domain annotation of trimeric autotransporter adhesins—daTAA

(2008) Pawel Szczesny et al.   BIOINFORMATICS

The head ofBartonellaadhesin A is crucial for host cell interaction ofBartonella henselae

(2008) Patrick O. Kaiser et al.   CELLULAR MICROBIOLOGY

The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil

(2008) Rebecca Conners et al.   EMBO JOURNAL

Localization of the Domains of the Haemophilus ducreyi Trimeric Autotransporter DsrA Involved in Serum Resistance and Binding to the Extracellular Matrix Proteins Fibronectin and Vitronectin

(2008) I. Leduc et al.   INFECTION AND IMMUNITY

Functional Mapping of YadA- and Ail-Mediated Binding of Human Factor H to Yersinia enterocolitica Serotype O:3

(2008) M. Biedzka-Sarek et al.   INFECTION AND IMMUNITY

Meningococcal Outer Membrane Protein NhhA Is Essential for Colonization and Disease by Preventing Phagocytosis and Complement Attack

(2008) H. Sjolinder et al.   INFECTION AND IMMUNITY

Contribution of Trimeric Autotransporter C-Terminal Domains of Oligomeric Coiled-Coil Adhesin (Oca) Family Members YadA, UspA1, EibA, and Hia to Translocation of the YadA Passenger Domain and Virulence of Yersinia enterocolitica

(2008) N. Ackermann et al.   JOURNAL OF BACTERIOLOGY

Identification of a Novel Trimeric Autotransporter Adhesin in the Cryptic Genospecies of Haemophilus

(2008) A. J. Sheets et al.   JOURNAL OF BACTERIOLOGY

Repetitive Architecture of the Haemophilus influenzae Hia Trimeric Autotransporter

(2008) Guoyu Meng et al.   JOURNAL OF MOLECULAR BIOLOGY

The Yersinia adhesin YadA binds to a collagenous triple-helical conformation but without sequence specificity

(2008) Jack C. Leo et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Structure of the Head of the Bartonella Adhesin BadA

(2008) Pawel Szczesny et al.   PLoS Pathogens