Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties

Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-β Peptide Accumulation

(2018) Julien Saint-Pol et al.   JOURNAL OF ALZHEIMERS DISEASE

The Regulation and Function of Lactate Dehydrogenase A: Therapeutic Potential in Brain Tumor

(2015) Cara J. Valvona et al.   BRAIN PATHOLOGY

The Pesticide Metabolites Paraoxon and Malaoxon Induce Cellular Death by Different Mechanisms in Cultured Human Pulmonary Cells

(2015) Daniel J. Angelini et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Gold Nanoparticles Increase Endothelial Paracellular Permeability by Altering Components of Endothelial Tight Junctions, and Increase Blood-Brain Barrier Permeability in Mice

(2015) Ching-Hao Li et al.   TOXICOLOGICAL SCIENCES

Acute disturbance of calcium homeostasis in PC12 cells as a novel mechanism of action for (sub)micromolar concentrations of organophosphate insecticides

(2014) Marieke Meijer et al.   NEUROTOXICOLOGY

A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells

(2014) Romeo Cecchelli et al.   PLoS One

Oxidative stress resulting from exposure of a human salivary gland cells to paraoxon: An in vitro model for organophosphate oral exposure

(2014) John M. Prins et al.   TOXICOLOGY IN VITRO

Reactive Oxygen Species-Caspase-3 Relationship in Mediating Blood-Brain Barrier Endothelial Cell Hyperpermeability Following Oxygen-Glucose Deprivation and Reoxygenation

(2013) Himakarnika Alluri et al.   MICROCIRCULATION

Attenuation of Dichlorvos-Induced Microglial Activation and Neuronal Apoptosis by 4-Hydroxy TEMPO

(2013) Aditya Sunkaria et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial dysfunction and organophosphorus compounds

(2013) Somayyeh Karami-Mohajeri et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of paraoxon on serum biochemical parameters and oxidative stress induction in various tissues of Wistar and Norway rats

(2012) Mahvash Jafari et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Transient alterations of the blood-brain barrier tight junction and receptor potential channel gene expression by chlorpyrifos

(2012) Wen Li et al.   JOURNAL OF APPLIED TOXICOLOGY

Reactive oxygen species regulated mitochondria-mediated apoptosis in PC12 cells exposed to chlorpyrifos

(2012) Jeong Eun Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Organophosphorus compound effects on neurotrophin receptors and intracellular signaling

(2012) Melinda Pomeroy-Black et al.   TOXICOLOGY IN VITRO

Caspase-3 Contributes to ZO-1 and Cl-5 Tight-Junction Disruption in Rapid Anoxic Neurovascular Unit Damage

(2011) Christoph M. Zehendner et al.   PLoS One

Improved Survival, Vascular Differentiation and Wound Healing Potential of Stem Cells Co-Cultured with Endothelial Cells

(2011) Dora C. S. Pedroso et al.   PLoS One

Paraoxon-Induced Protein Expression Changes to SH-SY5Y Cells

(2010) John M. Prins et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Assessments of tight junction proteins occludin, claudin 5 and scaffold proteins ZO1 and ZO2 in endothelial cells of the rat blood–brain barrier: Cellular responses to neurotoxicants malathion and lead acetate

(2010) Pergentino Balbuena et al.   NEUROTOXICOLOGY

Mice Treated with Chlorpyrifos or Chlorpyrifos Oxon Have Organophosphorylated Tubulin in the Brain and Disrupted Microtubule Structures, Suggesting a Role for Tubulin in Neurotoxicity Associated with Exposure to Organophosphorus Agents

(2010) Wei Jiang et al.   TOXICOLOGICAL SCIENCES

Mass spectral characterization of organophosphate-labeled lysine in peptides

(2009) Hasmik Grigoryan et al.   ANALYTICAL BIOCHEMISTRY

Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: Characteristic mass fragments and a new binding motif for organophosphates

(2009) Lawrence M. Schopfer et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Mass spectrometry identifies multiple organophosphorylated sites on tubulin

(2009) Hasmik Grigoryan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: A potential mechanism of long term toxicity by organophosphorus agents

(2008) Hasmik Grigoryan et al.   CHEMICO-BIOLOGICAL INTERACTIONS