Mice Treated with Chlorpyrifos or Chlorpyrifos Oxon Have Organophosphorylated Tubulin in the Brain and Disrupted Microtubule Structures, Suggesting a Role for Tubulin in Neurotoxicity Associated with Exposure to Organophosphorus Agents
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Title
Mice Treated with Chlorpyrifos or Chlorpyrifos Oxon Have Organophosphorylated Tubulin in the Brain and Disrupted Microtubule Structures, Suggesting a Role for Tubulin in Neurotoxicity Associated with Exposure to Organophosphorus Agents
Authors
Keywords
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Journal
TOXICOLOGICAL SCIENCES
Volume 115, Issue 1, Pages 183-193
Publisher
Oxford University Press (OUP)
Online
2010-02-09
DOI
10.1093/toxsci/kfq032
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- Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: A potential mechanism of long term toxicity by organophosphorus agents
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- Inhibition of extension outgrowth in differentiating rat C6 glioma cells by chlorpyrifos and chlorpyrifos oxon: Effects on microtubule proteins
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