Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors

Understanding Neurodevelopmental Disorders: The Promise of Regulatory Variation in the 3′UTRome

(2018) Kai A. Wanke et al.   BIOLOGICAL PSYCHIATRY

Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling

(2018) Justin Brumbaugh et al.   CELL

Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation

(2018) Yong Zhu et al.   MOLECULAR CELL

3′ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk

(2018) Hyun Jung Park et al.   NATURE GENETICS

Elavl3 is essential for the maintenance of Purkinje neuron axons

(2018) Yuki Ogawa et al.   Scientific Reports

Differential 3’ Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types

(2018) Saša Jereb et al.   eLife

Unraveling the Pathways to Neuronal Homeostasis and Disease: Mechanistic Insights into the Role of RNA-Binding Proteins and Associated Factors

(2018) Stylianos Ravanidis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting inCaenorhabditis elegansSomatic Tissues

(2017) Stephen M. Blazie et al.   GENETICS

Heterozygous HNRNPU variants cause early onset epilepsy and severe intellectual disability

(2017) Nuria C. Bramswig et al.   HUMAN GENETICS

IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α

(2017) Yuko Tanabe et al.   Nature Communications

Neuropathological and transcriptomic characteristics of the aged brain

(2017) Jeremy A Miller et al.   eLife

Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting inCaenorhabditis elegansSomatic Tissues

(2017) Stephen M. Blazie et al.   GENETICS

RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development

(2017) Ashley L. Lennox et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Alternative Polyadenylation: Methods, Findings, and Impacts

(2017) Wei Chen et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures

(2016) Slavé Petrovski et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Roar: detecting alternative polyadenylation with standard mRNA sequencing libraries

(2016) Elena Grassi et al.   BMC BIOINFORMATICS

A comprehensive transcriptional map of primate brain development

(2016) Trygve E. Bakken et al.   NATURE

Neurogenesis: Regulation by Alternative Splicing and Related Posttranscriptional Processes

(2016) Enrique Lara-Pezzi et al.   NEUROSCIENTIST

Expression of Quaking RNA-Binding Protein in the Adult and Developing Mouse Retina

(2016) Takahiko Suiko et al.   PLoS One

CircRNAs in the brain

(2016) Mor Hanan et al.   RNA Biology

Evolution and Biological Roles of Alternative 3′UTRs

(2016) Christine Mayr   TRENDS IN CELL BIOLOGY

Circular RNAs in Brain and Other Tissues: A Functional Enigma

(2016) Wei Chen et al.   TRENDS IN NEUROSCIENCES

Impact of the Autism-Associated Long Noncoding RNA MSNP1AS on Neuronal Architecture and Gene Expression in Human Neural Progenitor Cells

(2016) Jessica DeWitt et al.   Genes

Transcriptomes of post-mitotic neurons identify the usage of alternative pathways during adult and embryonic neuronal differentiation

(2015) Alexandra Tallafuss et al.   BMC GENOMICS

Molecular Identity of Human Outer Radial Glia during Cortical Development

(2015) Alex A. Pollen et al.   CELL

MicroRNAs: Small molecules with big roles in neurodevelopment and diseases

(2015) Emily Sun et al.   EXPERIMENTAL NEUROLOGY

A role for Rab23 in the trafficking of Kif17 to the primary cilium

(2015) Y. S. Lim et al.   JOURNAL OF CELL SCIENCE

Concentration and localization of co-expressed ELAV/Hu proteins control specificity of mRNA processing

(2015) Emanuela Zaharieva et al.   MOLECULAR AND CELLULAR BIOLOGY

ELAV Links Paused Pol II to Alternative Polyadenylation in the Drosophila Nervous System

(2015) Katarzyna Oktaba et al.   MOLECULAR CELL

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Alternative 3′ UTRs act as scaffolds to regulate membrane protein localization

(2015) Binyamin D. Berkovits et al.   NATURE

A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors

(2015) Donghua Zou et al.   Neural Development

A 3′ untranslated region variant inFMR1eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR

(2015) Joshua A. Suhl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternative polyadenylation coupled to transcription initiation: Insights from ELAV-mediated 3′ UTR extension

(2015) Valérie Hilgers   RNA Biology

The higher order auditory cortex is involved in the assignment of affective value to sensory stimuli

(2015) Anna Grosso et al.   Nature Communications

A post-transcriptional mechanism pacing expression of neural genes with precursor cell differentiation status

(2015) Weijun Dai et al.   Nature Communications

Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals Promoter DNA Methylation Dynamics

(2015) Francesco Neri et al.   Cell Reports

Full UPF3B function is critical for neuronal differentiation of neural stem cells

(2015) Tahani Alrahbeni et al.   Molecular Brain

Post-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brain

(2015) Louis-Jan Pilaz et al.   Wiley Interdisciplinary Reviews-RNA

Enhancer Analysis Unveils Genetic Interactions between TLX and SOX2 in Neural Stem Cells and In Vivo Reprogramming

(2015) Mohammed M. Islam et al.   Stem Cell Reports

The role of microRNAs in human neural stem cells, neuronal differentiation and subtype specification

(2014) Laura Stappert et al.   CELL AND TISSUE RESEARCH

RNA-binding protein research with transcriptome-wide technologies in neural development

(2014) Masato Yano et al.   CELL AND TISSUE RESEARCH

Cell cycle regulation of proliferation versus differentiation in the central nervous system

(2014) Laura J. A. Hardwick et al.   CELL AND TISSUE RESEARCH

Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33

(2014) Lars Schönemann et al.   GENES & DEVELOPMENT

MicroRNAs and synaptic plasticity--a mutual relationship

(2014) A. Aksoy-Aksel et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Temporally defined neocortical translation and polysome assembly are determined by the RNA-binding protein Hu antigen R

(2014) M. L. Kraushar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visual stimuli recruit intrinsically generated cortical ensembles

(2014) J.-e. K. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNAs: key triggers of neuronal cell fate

(2014) Karla F. Meza-Sosa et al.   Frontiers in Cellular Neuroscience

Effects of let-7b and TLX on the proliferation and differentiation of retinal progenitor cells in vitro

(2014) Ni Ni et al.   Scientific Reports

Non-coding RNAs in pluripotency and neural differentiation of human pluripotent stem cells

(2014) Dunja Lukovic et al.   Frontiers in Genetics

The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons

(2013) Tandis Vazin et al.   BIOMATERIALS

Ubiquitously transcribed genes use alternative polyadenylation to achieve tissue-specific expression

(2013) S. Lianoglou et al.   GENES & DEVELOPMENT

Widespread and extensive lengthening of 3' UTRs in the mammalian brain

(2013) P. Miura et al.   GENOME RESEARCH

The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth

(2013) Lachlan A. Jolly et al.   HUMAN MOLECULAR GENETICS

ELAV proteins along evolution: Back to the nucleus?

(2013) Claudia Colombrita et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Alternative cleavage and polyadenylation: extent, regulation and function

(2013) Ran Elkon et al.   NATURE REVIEWS GENETICS

A Matter of Balance: Role of Neurexin and Neuroligin at the Synapse

(2013) Marie Louise Bang et al.   NEUROCHEMICAL RESEARCH

The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development

(2013) Katherine L. Pettem et al.   NEURON

MicroRNAs as Neuronal Fate Determinants

(2013) Malin Åkerblom et al.   NEUROSCIENTIST

Genome-wide maps of polyadenylation reveal dynamic mRNA 3'-end formation in mammalian cell lineages

(2013) L. Wang et al.   RNA

Alternative cleavage and polyadenylation: the long and short of it

(2013) Bin Tian et al.   TRENDS IN BIOCHEMICAL SCIENCES

ELAV mediates 3' UTR extension in the Drosophila nervous system

(2012) V. Hilgers et al.   GENES & DEVELOPMENT

Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention

(2012) K. Yap et al.   GENES & DEVELOPMENT

Extensive alternative polyadenylation during zebrafish development

(2012) I. Ulitsky et al.   GENOME RESEARCH

RBFOX1 regulates both splicing and transcriptional networks in human neuronal development

(2012) Brent L. Fogel et al.   HUMAN MOLECULAR GENETICS

An anatomically comprehensive atlas of the adult human brain transcriptome

(2012) Michael J. Hawrylycz et al.   NATURE

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

(2012) Sika Zheng et al.   NATURE NEUROSCIENCE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Neuronal Elav-like (Hu) Proteins Regulate RNA Splicing and Abundance to Control Glutamate Levels and Neuronal Excitability

(2012) Gulayse Ince-Dunn et al.   NEURON

A conserved microRNA/NMD regulatory circuit controls gene expression

(2012) Rachid Karam et al.   RNA Biology

Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length

(2012) Georges Martin et al.   Cell Reports

Wnt5a Is a Transcriptional Target of Dlx Homeogenes and Promotes Differentiation of Interneuron Progenitors In Vitro and In Vivo

(2011) S. Paina et al.   JOURNAL OF NEUROSCIENCE

Activation of Postnatal Neural Stem Cells Requires Nuclear Receptor TLX

(2011) W. Niu et al.   JOURNAL OF NEUROSCIENCE

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay

(2011) Ivone G. Bruno et al.   MOLECULAR CELL

Genome-Wide Association Study of Schizophrenia in Japanese Population

(2011) Kazuo Yamada et al.   PLoS One

The structure of human Cleavage Factor Imhints at functions beyond UGUA-specific RNA binding

(2011) Qin Yang et al.   RNA Biology

Complex and dynamic landscape of RNA polyadenylation revealed by PAS-Seq

(2011) P. J. Shepard et al.   RNA

miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells

(2011) GuoQiang Sun et al.   Nature Communications

Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males

(2010) Stephen C. Collins et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Preservation of positional identity in fetus-derived neural stem (NS) cells from different mouse central nervous system compartments

(2010) Marco Onorati et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The β isotypes of tubulin in neuronal differentiation

(2010) Jiayan Guo et al.   Cytoskeleton

Understanding neuronal connectivity through the post-transcriptional toolkit

(2010) C. M. Loya et al.   GENES & DEVELOPMENT

PMEPA1 promotes androgen receptor-negative prostate cell proliferation through suppressing the Smad3/4-c-Myc-p21$^\rm Cip1$ signaling pathway

(2010) Rong Liu et al.   JOURNAL OF PATHOLOGY

Distinct 3'UTRs differentially regulate activity-dependent translation of brain-derived neurotrophic factor (BDNF)

(2010) A. G. Lau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

ZNRF1 interacts with tubulin and regulates cell morphogenesis

(2009) Koichi Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer

(2009) Junfang Ji et al.   NEW ENGLAND JOURNAL OF MEDICINE

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

(2008) Steven W. Flavell et al.   NEURON

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE