Potent MERS-CoV Fusion Inhibitory Peptides Identified from HR2 Domain in Spike Protein of Bat Coronavirus HKU4

Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains

(2018) Shuai Xia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding

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Discovery of Hydrocarbon-Stapled Short α-Helical Peptides as Promising Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Fusion Inhibitors

(2018) Chao Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

MERS-CoV spillover at the camel-human interface

(2018) Gytis Dudas et al.   eLife

De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery

(2018) Chao Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Adaptive Evolution of MERS-CoV to Species Variation in DPP4

(2018) Michael Letko et al.   Cell Reports

Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

(2017) S. J. Anthony et al.   mBio

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

(2017) Yuan Yuan et al.   Nature Communications

Creating an Artificial Tail Anchor as a Novel Strategy To Enhance the Potency of Peptide-Based HIV Fusion Inhibitors

(2016) Shan Su et al.   JOURNAL OF VIROLOGY

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) origin and animal reservoir

(2016) Hamzah A. Mohd et al.   Virology Journal

Tryptophan-Dependent Membrane Interaction and Heteromerization with the Internal Fusion Peptide by the Membrane Proximal External Region of SARS-CoV Spike Protein

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Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

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Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection

(2015) Rudragouda Channappanavar et al.   JOURNAL OF INFECTIOUS DISEASES

Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome Coronavirus

(2015) Yang Yang et al.   JOURNAL OF VIROLOGY

The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses

(2015) Diego Forni et al.   Scientific Reports

Urgent development of effective therapeutic and prophylactic agents to control the emerging threat of Middle East respiratory syndrome (MERS)

(2015) Lu Lu et al.   Emerging Microbes & Infections

Testing of Middle East Respiratory Syndrome Coronavirus Replication Inhibitors for the Ability To Block Viral Entry

(2014) Qi Liu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bat Origins of MERS-CoV Supported by Bat Coronavirus HKU4 Usage of Human Receptor CD26

(2014) Qihui Wang et al.   Cell Host & Microbe

Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus

(2014) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein

(2014) Shuai Xia et al.   VIRUS RESEARCH

Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus

(2014) M. Cotten et al.   mBio

Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor

(2014) Lu Lu et al.   Nature Communications

Identification of a Receptor-Binding Domain in the S Protein of the Novel Human Coronavirus Middle East Respiratory Syndrome Coronavirus as an Essential Target for Vaccine Development

(2013) L. Du et al.   JOURNAL OF VIROLOGY

Structure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome Coronavirus

(2013) J. Gao et al.   JOURNAL OF VIROLOGY

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26

(2013) Guangwen Lu et al.   NATURE

A safe and convenient pseudovirus-based inhibition assay to detect neutralizing antibodies and screen for viral entry inhibitors against the novel human coronavirus MERS-CoV

(2013) Guangyu Zhao et al.   Virology Journal

Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?

(2012) Jasper F.W. Chan et al.   JOURNAL OF INFECTION

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Coronavirus EMC Does Not Require the SARS-Coronavirus Receptor and Maintains Broad Replicative Capability in Mammalian Cell Lines

(2012) M. A. Muller et al.   mBio

Novel Recombinant Engineered gp41 N-terminal Heptad Repeat Trimers and Their Potential as Anti-HIV-1 Therapeutics or Microbicides

(2010) Xi Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coronavirus Diversity, Phylogeny and Interspecies Jumping

(2009) Patrick C. Y. Woo et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Importance of SARS-CoV spike protein Trp-rich region in viral infectivity

(2008) Yanning Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS