Novel Recombinant Engineered gp41 N-terminal Heptad Repeat Trimers and Their Potential as Anti-HIV-1 Therapeutics or Microbicides

In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20)

(2009) M.-A. Jenabian et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Detailed Mechanistic Insights into HIV-1 Sensitivity to Three Generations of Fusion Inhibitors

(2009) Dirk Eggink et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Baseplate Wedges of Bacteriophage T4 Spontaneously Assemble into Hubless Baseplate-Like Structure In Vitro

(2009) Moh Lan Yap et al.   JOURNAL OF MOLECULAR BIOLOGY

Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation

(2009) Gero Hütter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of the Enfuvirtide Resistance Mutation N43D and the Associated Baseline Polymorphism E137K on Peptide Sensitivity and Six-Helix Bundle Structure†‡

(2008) Xuefang Bai et al.   BIOCHEMISTRY

Identification of a Critical Motif for the Human Immunodeficiency Virus Type 1 (HIV-1) gp41 Core Structure: Implications for Designing Novel Anti-HIV Fusion Inhibitors

(2008) Y. He et al.   JOURNAL OF VIROLOGY

Tropism-independent protection of macaques against vaginal transmission of three SHIVs by the HIV-1 fusion inhibitor T-1249

(2008) R. S. Veazey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potent HIV fusion inhibitors against Enfuvirtide-resistant HIV-1 strains

(2008) Y. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant protein of heptad-repeat HR212, a stable fusion inhibitor with potent anti-HIV action in vitro

(2008) Wei Pang et al.   VIROLOGY

N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus

(2007) Antu K. Dey et al.   VIROLOGY

Sedimentation velocity studies of the high-molecular weight aggregates of the HIV gp41 ectodomain

(2004) Amy Jacobs et al.   PROTEIN SCIENCE

Modern analytical ultracentrifugation in protein science: A tutorial review

(2002) Jacob Lebowitz et al.   PROTEIN SCIENCE