Antimicrobial peptides activity in the skin

Significance of Skin Barrier Dysfunction in Atopic Dermatitis

(2018) Byung Eui Kim et al.   Allergy Asthma & Immunology Research

Friends or Foes? Host defense (antimicrobial) peptides and proteins in human skin diseases

(2017) François Niyonsaba et al.   EXPERIMENTAL DERMATOLOGY

Local Burn Injury Promotes Defects in the Epidermal Lipid and Antimicrobial Peptide Barriers in Human Autograft Skin and Burn Margin

(2017) Jennifer K. Plichta et al.   Journal of Burn Care & Research

Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides

(2017) Marta Zapotoczna et al.   JOURNAL OF INFECTIOUS DISEASES

Antimicrobial peptides: Role in human disease and potential as immunotherapies

(2017) César de la Fuente-Núñez et al.   PHARMACOLOGY & THERAPEUTICS

Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design

(2017) Jianguo Li et al.   Frontiers in Neuroscience

Membrane-active Antimicrobial Peptides as Template Structures for Novel Antibiotic Agents

(2016) Karl Lohner   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Antimicrobial peptides and wound healing: biological and therapeutic considerations

(2016) Maria Luisa Mangoni et al.   EXPERIMENTAL DERMATOLOGY

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

(2016) Hee-Kyoung Kang et al.   JOURNAL OF MICROBIOLOGY

TLR3 activation induces S100A7 to regulate keratinocyte differentiation after skin injury

(2016) Hu Lei et al.   Science China-Life Sciences

Therapeutic utility of antibacterial peptides in wound healing

(2015) Laszlo Otvos et al.   Expert Review of Anti-Infective Therapy

The antimicrobial protein S100A7/psoriasin enhances the expression of keratinocyte differentiation markers and strengthens the skin's tight junction barrier

(2014) F. Hattori et al.   BRITISH JOURNAL OF DERMATOLOGY

Local Burn Injury Impairs Epithelial Permeability and Antimicrobial Peptide Barrier Function in Distal Unburned Skin*

(2014) Jennifer K. Plichta et al.   CRITICAL CARE MEDICINE

The Development of Antimicrobial Peptides as New Antibacterial Drugs

(2014) Giulia Roscia et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Host Defense (Antimicrobial) Peptide, Human β-Defensin-3, Improves the Function of the Epithelial Tight-Junction Barrier in Human Keratinocytes

(2014) Chanisa Kiatsurayanon et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Novel Anti-Microbial Peptide SR-0379 Accelerates Wound Healing via the PI3 Kinase/Akt/mTOR Pathway

(2014) Hideki Tomioka et al.   PLoS One

Lineage−CD34+CD31+ Cells That Appear in Association with Severe Burn Injury Are Inhibitory on the Production of Antimicrobial Peptides by Epidermal Keratinocytes

(2014) Shohei Yoshida et al.   PLoS One

Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial

(2014) Alvar Grönberg et al.   WOUND REPAIR AND REGENERATION

Evaluation of a Nisin-Eluting Nanofiber Scaffold To Treat Staphylococcus aureus-Induced Skin Infections in Mice

(2013) Tiaan D. J. Heunis et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

What is the role of antimicrobial peptides (AMP) in acne vulgaris?

(2013) Jürgen Harder et al.   EXPERIMENTAL DERMATOLOGY

The Human Cathelicidin Antimicrobial Peptide LL-37 as a Potential Treatment for Polymicrobial Infected Wounds

(2013) Allen J. Duplantier et al.   Frontiers in Immunology

Cathelicidin LL-37: An Antimicrobial Peptide with a Role in Inflammatory Skin Disease

(2012) Markus Reinholz et al.   Annals of Dermatology

In VitroActivities of LTX-109, a Synthetic Antimicrobial Peptide, against Methicillin-Resistant, Vancomycin-Intermediate, Vancomycin-Resistant, Daptomycin-Nonsusceptible, and Linezolid-Nonsusceptible Staphylococcus aureus

(2012) Louis D. Saravolatz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The skin surface as antimicrobial barrier: present concepts and future outlooks

(2012) Jürgen Harder et al.   EXPERIMENTAL DERMATOLOGY

Pattern recognition receptors in infectious skin diseases

(2012) Heleen D. de Koning et al.   MICROBES AND INFECTION

Innate Defense Regulator Peptide 1018 in Wound Healing and Wound Infection

(2012) Lars Steinstraesser et al.   PLoS One

Natural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus

(2011) Scott N Dean et al.   BMC MICROBIOLOGY

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

(2011) Fiona Semple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

(2011) Mark Boguniewicz et al.   IMMUNOLOGICAL REVIEWS

The Coordinated Response of the Physical and Antimicrobial Peptide Barriers of the Skin

(2011) Andrew W. Borkowski et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Acne vulgaris

(2011) Hywel C Williams et al.   LANCET

Wound healing activity of the human antimicrobial peptide LL37

(2011) Reinaldo Ramos et al.   PEPTIDES

Susceptibility of Pseudomonas aeruginosa Biofilm to Alpha-Helical Peptides: D-enantiomer of LL-37

(2011) Scott N. Dean et al.   Frontiers in Microbiology

Antimicrobial Peptides in Healthy Skin and Atopic Dermatitis

(2011) Jens-M. Schröder   ALLERGOLOGY INTERNATIONAL

Describing the Mechanism of Antimicrobial Peptide Action with the Interfacial Activity Model

(2010) William C. Wimley   ACS Chemical Biology

Antimicrobial peptides: General overview and clinical implications in human health and disease

(2010) Eduardo Guaní-Guerra et al.   CLINICAL IMMUNOLOGY

Human β-defensin 3 has immunosuppressive activityin vitroandin vivo

(2010) Fiona Semple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Differential expression of antimicrobial peptides in margins of chronic wounds

(2010) Stefanie Dressel et al.   EXPERIMENTAL DERMATOLOGY

Enhanced Expression and Secretion of Antimicrobial Peptides in Atopic Dermatitis and after Superficial Skin Injury

(2010) Jürgen Harder et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Activation of TLR2 by a Small Molecule Produced by Staphylococcus epidermidis Increases Antimicrobial Defense against Bacterial Skin Infections

(2010) Yuping Lai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mechanical and Metabolic Injury to the Skin Barrier Leads to Increased Expression of Murine β-Defensin-1, -3, and -14

(2010) Kerstin Ahrens et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Commensals Amplify the Innate Immune Response to Pathogens by Activation of Distinct Signaling Pathways

(2010) Ines Wanke et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Vitamin D as an inducer of cathelicidin antimicrobial peptide expression: Past, present and future

(2010) John H. White   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

New developments in our understanding of acne pathogenesis and treatment

(2009) Ichiro Kurokawa et al.   EXPERIMENTAL DERMATOLOGY

Injury downregulates the expression of the human cathelicidin protein hCAP18/LL-37 in atopic dermatitis

(2009) Lotus Mallbris et al.   EXPERIMENTAL DERMATOLOGY

Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity

(2009) Constance Auvynet et al.   FEBS Journal

Antimicrobial peptides and the skin immune defense system

(2009) Jürgen Schauber et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo

(2009) Regine Gläser et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Histone H4 Is a Major Component of the Antimicrobial Action of Human Sebocytes

(2009) Dong-Youn Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Injury Is a Major Inducer of Epidermal Innate Immune Responses during Wound Healing

(2009) K. Markus Roupé et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Selective Antimicrobial Action Is Provided by Phenol-Soluble Modulins Derived from Staphylococcus epidermidis, a Normal Resident of the Skin

(2009) Anna L. Cogen et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating β-Defensin-2 Expression

(2009) Teruaki Nakatsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

(2009) Yuping Lai et al.   TRENDS IN IMMUNOLOGY

Microanalysis of an antimicrobial peptide, β-defensin-2, in the stratum corneum from patients with atopic dermatitis

(2008) S. Asano et al.   BRITISH JOURNAL OF DERMATOLOGY

The human antimicrobial peptide dermcidin activates normal human keratinocytes

(2008) F. Niyonsaba et al.   BRITISH JOURNAL OF DERMATOLOGY

Topical versus Systemic Antimicrobial Therapy for Treating Mildly Infected Diabetic Foot Ulcers: A Randomized, Controlled, Double‐Blinded, Multicenter Trial of Pexiganan Cream

(2008) Benjamin A. Lipsky et al.   CLINICAL INFECTIOUS DISEASES

The role of the multifunctional peptide LL-37 in host defense

(2008) Ylva Kai-Larsen   Frontiers in Bioscience-Landmark

Microbicidal protein psoriasin is a multifunctional modulator of neutrophil activation

(2008) Yan Zheng et al.   IMMUNOLOGY

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation

(2008) J. Overhage et al.   INFECTION AND IMMUNITY

The Neuroendocrine Peptide Catestatin Is a Cutaneous Antimicrobial and Induced in the Skin after Injury

(2008) Katherine A. Radek et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Sebocytes Express Functional Cathelicidin Antimicrobial Peptides and Can Act to Kill Propionibacterium Acnes

(2008) Dong-Youn Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Antimicrobial Protein Psoriasin (S100A7) Is Upregulated in Atopic Dermatitis and after Experimental Skin Barrier Disruption

(2008) Regine Gläser et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Gr-1+CD11b+ cells as an accelerator of sepsis stemming from Pseudomonas aeruginosa wound infection in thermally injured mice

(2008) M. Kobayashi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

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(2008) Lars Steinstraesser et al.   MOLECULAR MEDICINE

Co-Regulation and Interdependence of the Mammalian Epidermal Permeability and Antimicrobial Barriers

(2007) Karin M. Aberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Skin Peptides: Biological Activity and Therapeutic Opportunities

(2007) Sarika Namjoshi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES