Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation

Obesity-induced cardiac lipid accumulation in adult mice is modulated by G protein-coupled receptor kinase 2 levels

(2016) Elisa Lucas et al.   Cardiovascular Diabetology

Radiofrequency Renal Denervation Protects the Ischemic Heart via Inhibition of GRK2 and Increased Nitric Oxide SignalingNovelty and Significance

(2016) David J. Polhemus et al.   CIRCULATION RESEARCH

Cardiac Fibroblast GRK2 Deletion Enhances Contractility and Remodeling Following Ischemia/Reperfusion InjuryNovelty and Significance

(2016) Meryl C. Woodall et al.   CIRCULATION RESEARCH

Regulator of G Protein Signaling 6 Protects the Heart from Ischemic Injury

(2016) Boyd R. Rorabaugh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

β2-Adrenergic receptor-dependent chemokine receptor 2 expression regulates leukocyte recruitment to the heart following acute injury

(2016) Laurel A. Grisanti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac FunctionNovelty and Significance

(2015) Konstantinos Drosatos et al.   CIRCULATION RESEARCH

Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice

(2015) Joshua Abd Alla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRK2 compromises cardiomyocyte mitochondrial function by diminishing fatty acid-mediated oxygen consumption and increasing superoxide levels

(2015) Priscila Y. Sato et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Evolving Impact of G Protein-Coupled Receptor Kinases in Cardiac Health and Disease

(2015) Priscila Y. Sato et al.   PHYSIOLOGICAL REVIEWS

Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2

(2015) Rocio Vila-Bedmar et al.   Science Signaling

Reversal of diet-induced obesity and insulin resistance by inducible genetic ablation of GRK2

(2015) Rocio Vila-Bedmar et al.   Science Signaling

Cardiac Fibroblast Glycogen Synthase Kinase-3β Regulates Ventricular Remodeling and Dysfunction in Ischemic Heart

(2014) Hind Lal et al.   CIRCULATION

Prodeath Signaling of G Protein–Coupled Receptor Kinase 2 in Cardiac Myocytes After Ischemic Stress Occurs Via Extracellular Signal–Regulated Kinase-Dependent Heat Shock Protein 90–Mediated Mitochondrial Targeting

(2013) Mai Chen et al.   CIRCULATION RESEARCH

Inhibition of G-protein-coupled Receptor Kinase 2 (GRK2) Triggers the Growth-promoting Mitogen-activated Protein Kinase (MAPK) Pathway

(2013) Xuebin Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myocardial Ablation of G Protein–Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway

(2013) Qian Fan et al.   PLoS One

Convergence of G Protein-Coupled Receptor and S-Nitrosylation Signaling Determines the Outcome to Cardiac Ischemic Injury

(2013) Z. M. Huang et al.   Science Signaling

Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury

(2012) John R. Ussher et al.   CARDIOVASCULAR RESEARCH

Cardiac G-Protein–Coupled Receptor Kinase 2 Ablation Induces a Novel Ca 2+ Handling Phenotype Resistant to Adverse Alterations and Remodeling After Myocardial Infarction

(2012) Philip W. Raake et al.   CIRCULATION

Standardized bioenergetic profiling of adult mouse cardiomyocytes

(2012) Ryan D. Readnower et al.   PHYSIOLOGICAL GENOMICS

Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis

(2011) Anna Fusco et al.   CELLULAR SIGNALLING

A novel GRK2/HDAC6 interaction modulates cell spreading and motility

(2011) Vanesa Lafarga et al.   EMBO JOURNAL

Level of G protein–Coupled Receptor Kinase-2 Determines Myocardial Ischemia/Reperfusion Injury via Pro- and Anti-Apoptotic Mechanisms

(2010) Henriette Brinks et al.   CIRCULATION RESEARCH

A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse

(2010) Erhe Gao et al.   CIRCULATION RESEARCH

Cargo sorting into multivesicular bodies in vitro

(2009) J. H. Tran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA