CD45 exclusion– and cross-linking–based receptor signaling together broaden FcεRI reactivity

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis

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Mast cells form antibody-dependent degranulatory synapse for dedicated secretion and defence

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Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

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Small molecule inhibition of Csk alters affinity recognition by T cells

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Helminth Allergens, Parasite-Specific IgE, and Its Protective Role in Human Immunity

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The large ectodomains of CD45 and CD148 regulate their segregation from and inhibition of ligated T-cell receptor

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The genomes of four tapeworm species reveal adaptations to parasitism

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Non-catalytic tyrosine-phosphorylated receptors

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Biophysical mechanism of T-cell receptor triggering in a reconstituted system

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Elucidating membrane structure and protein behavior using giant plasma membrane vesicles

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Most Highly Cytokinergic IgEs Have Polyreactivity to Autoantigens

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The regulation of integrin function by divalent cations

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Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI

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What Controls T Cell Receptor Phosphorylation?

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Ligand dimensions are important in controlling NK-cell responses

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Transient Dimers of Allergens

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Matched Sizes of Activating and Inhibitory Receptor/Ligand Pairs Are Required for Optimal Signal Integration by Human Natural Killer Cells

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Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand–receptor systems

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Determinants of allergenicity

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Formation of a Mast Cell Synapse: Fc RI Membrane Dynamics upon Binding Mobile or Immobilized Ligands on Surfaces

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Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide–MHC class II complexes to CD4+ T cells

(2009) Tomohiro Yoshimoto et al.   NATURE IMMUNOLOGY

MHC class II–dependent basophil–CD4+ T cell interactions promote TH2 cytokine–dependent immunity

(2009) Jacqueline G Perrigoue et al.   NATURE IMMUNOLOGY

Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

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A current understanding of FcɛRI-dependent mast cell activation

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Uteroglobin interacts with the heparin-binding site of fibronectin and prevents fibronectin-IgA complex formation found in IgA-nephropathy

(2008) Bhabadeb Chowdhury et al.   FEBS LETTERS

Allergens are distributed into few protein families and possess a restricted number of biochemical functions

(2008) Christian Radauer et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential Dephosphorylation of the FcRγ Immunoreceptor Tyrosine-based Activation Motif Tyrosines with Dissimilar Potential for Activating Syk

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Crystal Structures of Mite Allergens Der f 1 and Der p 1 Reveal Differences in Surface-Exposed Residues that May Influence Antibody Binding

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