Altered Levels of Long NcRNAs Meg3 and Neat1 in Cell And Animal Models Of Huntington’s Disease

Functional Classification and Experimental Dissection of Long Noncoding RNAs

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Multiple Layers of CDK5R1 Regulation in Alzheimer’s Disease Implicate Long Non-Coding RNAs

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Long non-coding RNA NEAT1 is a transcriptional target of p53 and modulates p53-induced transactivation and tumor-suppressor function

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The long non-coding RNA NEAT1 is responsive to neuronal activity and is associated with hyperexcitability states

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Emerging role of long noncoding RNAs as regulators of innate immune cell development and inflammatory gene expression

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Altered Expression of the Long Noncoding RNA NEAT1 in Huntington’s Disease

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miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement

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MicroRNA-124 slows down the progression of Huntington′s disease by promoting neurogenesis in the striatum

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The striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo

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Invited Review: Decoding the pathophysiological mechanisms that underlie RNA dysregulation in neurodegenerative disorders: a review of the current state of the art

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Control of Chromatin Structure by Long Noncoding RNA

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Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells

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Evidence of Extensive Alternative Splicing in Post Mortem Human Brain HTT Transcription by mRNA Sequencing

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RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

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A common gene expression signature in Huntington’s disease patient brain regions

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Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1 

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Ubiquitin-Activating Enzyme Activity Contributes to Differential Accumulation of Mutant Huntingtin in Brain and Peripheral Tissues

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The Long Noncoding RNAs NEAT1 and MALAT1 Bind Active Chromatin Sites

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Integrating the roles of long and small non-coding RNA in brain function and disease

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Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival

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Differential ubiquitination and degradation of huntingtin fragments modulated by ubiquitin-protein ligase E3A

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Functional interactions among microRNAs and long noncoding RNAs

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A prominent and conserved role for YY1 in Xist transcriptional activation

(2014) Mélanie Makhlouf et al.   Nature Communications

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

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MicroRNA-124 targets CCNA2 and regulates cell cycle in STHdhQ111/HdhQ111 cells

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NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies

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Autophagy and apoptosis dysfunction in neurodegenerative disorders

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Neuronal dark matter: the emerging role of microRNAs in neurodegeneration

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The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis

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Multiple knockout mouse models reveal lincRNAs are required for life and brain development

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Emerging roles of non-coding RNAs in brain evolution, development, plasticity and disease

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Mechanism(s) of Alteration of Micro RNA Expressions in Huntington’s Disease and Their Possible Contributions to the Observed Cellular and Molecular Dysfunctions in the Disease

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ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data

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A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression

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What have we learned from gene expression profiles in Huntington's disease?

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Long non-coding RNAs in Huntington's disease neurodegeneration

(2011) Rory Johnson   NEUROBIOLOGY OF DISEASE

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Micro RNA -214,-150,-146a and-125b targetHuntingtingene

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Inhibiting the ubiquitin–proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments

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Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease

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PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes

(2010) Andreas Ruepp et al.   GENOME BIOLOGY

Altered cholesterol and fatty acid metabolism in Huntington disease

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Systems genetics of complex traits in Drosophila melanogaster

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Huntington's disease: from pathology and genetics to potential therapies

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Quantitative gene expression profiling of mouse brain regions reveals differential transcripts conserved in human and affected in disease models

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