Glucocorticoid-induced enhancement of extinction—from animal models to clinical trials

Alpha-Adrenergic Receptors in PTSD — Failure or Time for Precision Medicine?

(2018) Kerry J. Ressler   NEW ENGLAND JOURNAL OF MEDICINE

Cortisol increases the return of fear by strengthening amygdala signaling in men

(2018) Valerie L. Kinner et al.   PSYCHONEUROENDOCRINOLOGY

Neural Underpinnings of Cortisol Effects on Fear Extinction

(2017) Christian Josef Merz et al.   NEUROPSYCHOPHARMACOLOGY

Pretreatment biomarkers predicting PTSD psychotherapy outcomes: A systematic review

(2017) Peter J. Colvonen et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The effects of acute stress on episodic memory: A meta-analysis and integrative review.

(2017) Grant S. Shields et al.   PSYCHOLOGICAL BULLETIN

The Effect of Dexamethasone on Symptoms of Posttraumatic Stress Disorder and Depression After Cardiac Surgery and Intensive Care Admission

(2016) Lotte Kok et al.   CRITICAL CARE MEDICINE

Acute Stress Suppresses Synaptic Inhibition and Increases Anxiety via Endocannabinoid Release in the Basolateral Amygdala

(2016) S. Di et al.   JOURNAL OF NEUROSCIENCE

Sex differences in stress effects on emotional learning

(2016) Christian J. Merz et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Stress, glucocorticoids and memory: implications for treating fear-related disorders

(2016) Dominique de Quervain et al.   NATURE REVIEWS NEUROSCIENCE

Cortisol disrupts the neural correlates of extinction recall

(2016) Valerie L. Kinner et al.   NEUROIMAGE

Severe stress hormone conditions cause an extended window of excitability in the mouse basolateral amygdala

(2016) Henk Karst et al.   NEUROPHARMACOLOGY

Glucocorticoid Administration Improves Aberrant Fear-Processing Networks in Spider Phobia

(2016) Masahito Nakataki et al.   NEUROPSYCHOPHARMACOLOGY

Timing matters: Endogenous cortisol mediates benefits from early-day psychotherapy

(2016) Alicia E. Meuret et al.   PSYCHONEUROENDOCRINOLOGY

Glucocorticoids mediate stress-induced impairment of retrieval of stimulus-response memory

(2016) Piray Atsak et al.   PSYCHONEUROENDOCRINOLOGY

Escitalopram reversed the traumatic stress-induced depressed and anxiety-like symptoms but not the deficits of fear memory

(2016) Chen-Cheng Lin et al.   PSYCHOPHARMACOLOGY

Lower Methylation of Glucocorticoid Receptor Gene Promoter 1F in Peripheral Blood of Veterans with Posttraumatic Stress Disorder

(2015) Rachel Yehuda et al.   BIOLOGICAL PSYCHIATRY

HPA AXIS RELATED GENES AND RESPONSE TO PSYCHOLOGICAL THERAPIES: GENETICS AND EPIGENETICS

(2015) Susanna Roberts et al.   DEPRESSION AND ANXIETY

A Mixed Glucocorticoid/Mineralocorticoid Selective Modulator With Dominant Antagonism in the Male Rat Brain

(2015) Erika Atucha et al.   ENDOCRINOLOGY

Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals

(2015) Leandro F. Vendruscolo et al.   JOURNAL OF CLINICAL INVESTIGATION

The rs1049353 Polymorphism in the CNR1 Gene Interacts With Childhood Abuse to Predict Posttraumatic Threat Symptoms

(2015) Natalie Mota et al.   JOURNAL OF CLINICAL PSYCHIATRY

Training-Associated Emotional Arousal Shapes Endocannabinoid Modulation of Spatial Memory Retrieval in Rats

(2015) M. Morena et al.   JOURNAL OF NEUROSCIENCE

No evidence for differential dose effects of hydrocortisone on intrusive memories in female patients with complex post-traumatic stress disorder – a randomized, double-blind, placebo-controlled, crossover study

(2015) Petra Ludäscher et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Stimulation of the mineralocorticoid receptor improves memory in young and elderly healthy individuals

(2015) Kim Hinkelmann et al.   NEUROBIOLOGY OF AGING

FKBP5 risk alleles and the development of intrusive memories

(2015) Jessica Cheung et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

The Vasopressin 1b Receptor Antagonist A-988315 Blocks Stress Effects on the Retrieval of Object-Recognition Memory

(2015) Areg Barsegyan et al.   NEUROPSYCHOPHARMACOLOGY

Neurobiological Interactions Between Stress and the Endocannabinoid System

(2015) Maria Morena et al.   NEUROPSYCHOPHARMACOLOGY

Gene–Stress–Epigenetic Regulation of FKBP5: Clinical and Translational Implications

(2015) Anthony S Zannas et al.   NEUROPSYCHOPHARMACOLOGY

Hydrocortisone accelerates the decay of iconic memory traces: On the modulation of executive and stimulus-driven constituents of sensory information maintenance

(2015) Robert Miller et al.   PSYCHONEUROENDOCRINOLOGY

Cortisol augmentation of a psychological treatment for warfighters with posttraumatic stress disorder: Randomized trial showing improved treatment retention and outcome

(2015) Rachel Yehuda et al.   PSYCHONEUROENDOCRINOLOGY

The efficacy of nabilone, a synthetic cannabinoid, in the treatment of PTSD-associated nightmares: A preliminary randomized, double-blind, placebo-controlled cross-over design study

(2015) Rakesh Jetly et al.   PSYCHONEUROENDOCRINOLOGY

Brain disorders? Precisely

(2015) T. R. Insel et al.   SCIENCE

Effects of cortisol administration on craving in heroin addicts

(2015) M Walter et al.   Translational Psychiatry

Preliminary, Open-Label, Pilot Study of Add-On Oral Δ9-Tetrahydrocannabinol in Chronic Post-Traumatic Stress Disorder

(2014) Pablo Roitman et al.   CLINICAL DRUG INVESTIGATION

Endocannabinoid-mediated retrograde modulation of synaptic transmission

(2014) Takako Ohno-Shosaku et al.   CURRENT OPINION IN NEUROBIOLOGY

Clinical effectiveness of interventions for treatment-resistant anxiety in older people: a systematic review

(2014) Samantha Barton et al.   HEALTH TECHNOLOGY ASSESSMENT

Epigenetic Modification of the Glucocorticoid Receptor Gene Is Linked to Traumatic Memory and Post-Traumatic Stress Disorder Risk in Genocide Survivors

(2014) V. Vukojevic et al.   JOURNAL OF NEUROSCIENCE

Acute stress impairs the retrieval of extinction memory in humans

(2014) Candace M. Raio et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Endocannabinoid Signaling within the Basolateral Amygdala Integrates Multiple Stress Hormone Effects on Memory Consolidation

(2014) Piray Atsak et al.   NEUROPSYCHOPHARMACOLOGY

Glucocorticoids interact with noradrenergic activation at encoding to enhance long-term memory for emotional material in women

(2014) S.K. Segal et al.   NEUROSCIENCE

Control of synaptic function by endocannabinoid-mediated retrograde signaling

(2014) Masanobu KANO   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training

(2014) Maria Morena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stress following extinction learning leads to a context-dependent return of fear

(2014) Tanja C. Hamacher-Dang et al.   PSYCHOPHYSIOLOGY

Dynamic adaptation of large-scale brain networks in response to acute stressors

(2014) Erno J. Hermans et al.   TRENDS IN NEUROSCIENCES

The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder

(2014) S Wilker et al.   Translational Psychiatry

Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder

(2014) B Labonté et al.   Translational Psychiatry

Fear Extinction and Relapse: State of the Art

(2013) Bram Vervliet et al.   Annual Review of Clinical Psychology

The efficacy of initial hydrocortisone administration at preventing posttraumatic distress in adult trauma patients: a randomized trial

(2013) Douglas L. Delahanty et al.   CNS SPECTRUMS

GLUCOCORTICOIDS ENHANCE IN VIVO EXPOSURE-BASED THERAPY OF SPIDER PHOBIA

(2013) Leila M. Soravia et al.   DEPRESSION AND ANXIETY

Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study

(2013) A Neumeister et al.   MOLECULAR PSYCHIATRY

Stress impairs retrieval of extinguished and unextinguished associations in a predictive learning task

(2013) Tanja C. Hamacher-Dang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Blocking Mineralocorticoid Receptors Impairs, Blocking Glucocorticoid Receptors Enhances Memory Retrieval in Humans

(2013) Ulrike Rimmele et al.   NEUROPSYCHOPHARMACOLOGY

Exposure to stress attenuates fear retrieval in healthy men

(2013) Christian J. Merz et al.   PSYCHONEUROENDOCRINOLOGY

Deficits in Conditioned Fear Extinction in Obsessive-Compulsive Disorder and Neurobiological Changes in the Fear Circuit

(2013) Mohammed R. Milad et al.   JAMA Psychiatry

Sustained incentive value of heroin-related cues in short- and long-term abstinent heroin users

(2012) Katrin H. Preller et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Glucocorticoid receptors recruit the CaMKIIα-BDNF-CREB pathways to mediate memory consolidation

(2012) Dillon Y Chen et al.   NATURE NEUROSCIENCE

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Biological studies of post-traumatic stress disorder

(2012) Roger K. Pitman et al.   NATURE REVIEWS NEUROSCIENCE

A current overview of cannabinoids and glucocorticoids in facilitating extinction of aversive memories: Potential extinction enhancers

(2012) Rafael Mariano de Bitencourt et al.   NEUROPHARMACOLOGY

Glucocorticoids interact with the hippocampal endocannabinoid system in impairing retrieval of contextual fear memory

(2012) P. Atsak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BclI polymorphism of the glucocorticoid receptor gene is associated with emotional memory performance in healthy individuals

(2012) Sandra Ackermann et al.   PSYCHONEUROENDOCRINOLOGY

Post-extinction fluoxetine treatment prevents stress-induced reemergence of extinguished fear

(2012) Olivier Deschaux et al.   PSYCHOPHARMACOLOGY

The clinical significance of drug craving

(2011) Stephen T. Tiffany et al.   Annals of the New York Academy of Sciences

Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress

(2011) Mohammed R. Milad et al.   Annual Review of Psychology

Using Polymorphisms in FKBP5 to Define Biologically Distinct Subtypes of Posttraumatic Stress Disorder

(2011) Divya Mehta   ARCHIVES OF GENERAL PSYCHIATRY

Memory modulation.

(2011) Benno Roozendaal et al.   BEHAVIORAL NEUROSCIENCE

High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: Interplay between clinical and animal studies

(2011) Joseph Zohar et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Impairment of Fear Memory Consolidation in Maternally Stressed Male Mouse Offspring: Evidence for Nongenomic Glucocorticoid Action on the Amygdala

(2011) E. J. Lee et al.   JOURNAL OF NEUROSCIENCE

The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives

(2011) Eva M Marco et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Combined β-adrenergic and corticosteroid receptor activation regulates AMPA receptor function in hippocampal neurons

(2011) Ming Zhou et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Block of glucocorticoid synthesis during re-activation inhibits extinction of an established fear memory

(2011) Jacqueline Blundell et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Glucocorticoids are required for extinction of predator stress-induced hyperarousal

(2011) Rachel Clay et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Role of the endocannabinoid system in regulating glucocorticoid effects on memory for emotional experiences

(2011) P. Atsak et al.   NEUROSCIENCE

Stress effects on memory: An update and integration

(2011) Lars Schwabe et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Glucocorticoids enhance extinction-based psychotherapy

(2011) D. J.- F. de Quervain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoids act on glutamatergic pathways to affect memory processes

(2011) Carmen Sandi   TRENDS IN NEUROSCIENCES

Pre-Existing High Glucocorticoid Receptor Number Predicting Development of Posttraumatic Stress Symptoms After Military Deployment

(2010) Mirjam van Zuiden et al.   AMERICAN JOURNAL OF PSYCHIATRY

Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy

(2010) Daniela Hauer et al.   CRITICAL CARE MEDICINE

Fast Feedback Inhibition of the HPA Axis by Glucocorticoids Is Mediated by Endocannabinoid Signaling

(2010) Nathan K. Evanson et al.   ENDOCRINOLOGY

Membrane-Associated Glucocorticoid Activity Is Necessary for Modulation of Long-Term Memory via Chromatin Modification

(2010) B. Roozendaal et al.   JOURNAL OF NEUROSCIENCE

Stress hormones and AMPA receptor trafficking in synaptic plasticity and memory

(2010) Harmen J. Krugers et al.   NATURE REVIEWS NEUROSCIENCE

Morphine Use after Combat Injury in Iraq and Post-Traumatic Stress Disorder

(2010) Troy Lisa Holbrook et al.   NEW ENGLAND JOURNAL OF MEDICINE

Glucocorticoids in the prefrontal cortex enhance memory consolidation and impair working memory by a common neural mechanism

(2010) A. Barsegyan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid elevations in limbic endocannabinoid content by glucocorticoid hormones in vivo

(2010) Matthew N. Hill et al.   PSYCHONEUROENDOCRINOLOGY

Effects of single cortisol administrations on human affect reviewed: Coping with stress through adaptive regulation of automatic cognitive processing

(2010) Peter Putman et al.   PSYCHONEUROENDOCRINOLOGY

Implications of psychosocial stress on memory formation in a typical male versus female student sample

(2010) Sandra Cornelisse et al.   PSYCHONEUROENDOCRINOLOGY

Corticosteroids: way upstream

(2010) Therese Riedemann et al.   Molecular Brain

Stress and memory in humans: Twelve years of progress?

(2009) Oliver T. Wolf   BRAIN RESEARCH

Glucocorticoids and the regulation of memory in health and disease

(2009) Dominique J.-F. de Quervain et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Stress, memory and the amygdala

(2009) Benno Roozendaal et al.   NATURE REVIEWS NEUROSCIENCE

The neuro-symphony of stress

(2009) Marian Joëls et al.   NATURE REVIEWS NEUROSCIENCE

Neural regulation of endocrine and autonomic stress responses

(2009) Yvonne M. Ulrich-Lai et al.   NATURE REVIEWS NEUROSCIENCE

Post-learning psychosocial stress enhances consolidation of neutral stimuli

(2009) Diana Preuß et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Memory-enhancing corticosterone treatment increases amygdala norepinephrine and Arc protein expression in hippocampal synaptic fractions

(2009) Jayme R. McReynolds et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Stress at Learning Facilitates Memory Formation by Regulating AMPA Receptor Trafficking Through a Glucocorticoid Action

(2009) Lisa Conboy et al.   NEUROPSYCHOPHARMACOLOGY

Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory

(2009) P. Campolongo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder

(2008) Ake T. Lu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Glucocorticoid Therapy-Induced Memory Deficits: Acute versus Chronic Effects

(2008) D. Coluccia et al.   JOURNAL OF NEUROSCIENCE

Immediate and prolonged effects of cortisol, but not propranolol, on memory retrieval in healthy young men

(2008) Marieke S. Tollenaar et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

True or false? Memory is differentially affected by stress-induced cortisol elevations and sympathetic activity at consolidation and retrieval

(2008) Tom Smeets et al.   PSYCHONEUROENDOCRINOLOGY

Stress effects on declarative memory retrieval are blocked by a β-adrenoceptor antagonist in humans

(2008) Lars Schwabe et al.   PSYCHONEUROENDOCRINOLOGY