Ameliorative effect of fisetin against lipopolysaccharide and restraint stress-induced behavioral deficits via modulation of NF-κB and IDO-1

TLR4-NF-κB Signal Involved in Depressive-Like Behaviors and Cytokine Expression of Frontal Cortex and Hippocampus in Stressed C57BL/6 and ob/ob Mice

(2018) Yihe Wang et al.   NEURAL PLASTICITY

Glibenclamide protects against thioacetamide-induced hepatic damage in Wistar rat: investigation on NLRP3, MMP-2, and stellate cell activation

(2018) Durgesh Kumar Dwivedi et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Fisetin Regulates Nrf2 Expression and the Inflammation-Related Signaling Pathway to Prevent UVB-Induced Skin Damage in Hairless Mice

(2017) Po-Yuan Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cognitive deficits induced by combined exposure of stress and alcohol mediated through oxidative stress-PARP pathway in the hippocampus

(2017) Rajat Pant et al.   NEUROSCIENCE LETTERS

Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway

(2017) Ying Guo et al.   Scientific Reports

Sodium Phenylbutyrate and Edaravone Abrogate Chronic Restraint Stress-Induced Behavioral Deficits: Implication of Oxido-Nitrosative, Endoplasmic Reticulum Stress Cascade, and Neuroinflammation

(2016) Ashok Jangra et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice

(2016) Ashok Jangra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lipopolysaccharide-Induced Behavioral Alterations Are Alleviated by Sodium Phenylbutyrate via Attenuation of Oxidative Stress and Neuroinflammatory Cascade

(2016) Ashok Jangra et al.   INFLAMMATION

Fisetin, a dietary flavonoid, ameliorates experimental colitis in mice: Relevance of NF-κB signaling

(2016) Bidya Dhar Sahu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effect of water-immersion restraint stress on tryptophan catabolism through the kynurenine pathway in rat tissues

(2016) Yoshiji Ohta et al.   Journal of Physiological Sciences

The effects of fisetin on lipopolysaccharide-induced depressive-like behavior in mice

(2016) Xuefeng Yu et al.   METABOLIC BRAIN DISEASE

7,8-Dihydroxyflavone reverses the depressive symptoms in mouse chronic mild stress

(2016) Min-Wang Zhang et al.   NEUROSCIENCE LETTERS

7,8-Dihydroxyflavone, a Tropomyosin-Kinase Related Receptor B Agonist, Produces Fast-Onset Antidepressant-Like Effects in Rats Exposed to Chronic Mild Stress

(2016) Hsin-An Chang et al.   Psychiatry Investigation

Brain-derived neurotrophic factor and its clinical implications

(2015) Siresha Bathina et al.   Archives of Medical Science

Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways

(2015) Joanna D. Wardyn et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory

(2015) Jillian M. Heisler et al.   BRAIN BEHAVIOR AND IMMUNITY

Experimental immunology The effects of EGb761 on lipopolysaccharide-induced depressive-like behaviour in C57BL/6J mice

(2015) Yuehan Zhao et al.   Central European Journal of Immunology

Fisetin Alleviates Lipopolysaccharide-Induced Acute Lung Injury via TLR4-Mediated NF-κB Signaling Pathway in Rats

(2015) Guang Feng et al.   INFLAMMATION

Dietary flavonoid fisetin regulates aluminium chloride-induced neuronal apoptosis in cortex and hippocampus of mice brain

(2015) Dharmalingam Prakash et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level

(2015) Prajapati Kasbe et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice

(2015) Chandra Shaker Sriram et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression

(2015) Ji-chun Zhang et al.   PSYCHOPHARMACOLOGY

Fisetin exerts antihyperalgesic effect in a mouse model of neuropathic pain: engagement of spinal serotonergic system

(2015) Xin Zhao et al.   Scientific Reports

Flavonoid-Based Therapies in the Early Management of Neurodegenerative Diseases

(2015) Isha Solanki et al.   Advances in Nutrition

Hyperglycemia induces memory impairment linked to increased acetylcholinesterase activity in zebrafish (Danio rerio)

(2014) Katiucia Marques Capiotti et al.   BEHAVIOURAL BRAIN RESEARCH

Diet-induced obesity progressively alters cognition, anxiety-like behavior and lipopolysaccharide-induced depressive-like behavior: Focus on brain indoleamine 2,3-dioxygenase activation

(2014) Caroline André et al.   BRAIN BEHAVIOR AND IMMUNITY

Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice

(2014) Kunjbihari Sulakhiya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice

(2014) Ashok Jangra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice

(2013) Antonio Currais et al.   AGING CELL

Effects of chronic social defeat stress on behaviour, endoplasmic reticulum proteins and choline acetyltransferase in adolescent mice

(2013) Guang-Biao Huang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Fisetin Enhances Behavioral Performances and Attenuates Reactive Gliosis and Inflammation During Aluminum Chloride-Induced Neurotoxicity

(2013) Dharmalingam Prakash et al.   NEUROMOLECULAR MEDICINE

Regulated Extracellular Choline Acetyltransferase Activity— The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway

(2013) Swetha Vijayaraghavan et al.   PLoS One

Inhibition of Choline Acetyltransferase as a Mechanism for Cholinergic Dysfunction Induced by Amyloid-β Peptide Oligomers

(2012) Nilson Nunes-Tavares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The antidepressant-like effect of fisetin involves the serotonergic and noradrenergic system

(2011) Linlin Zhen et al.   BEHAVIOURAL BRAIN RESEARCH

Neuroprotective Actions of Flavonoids

(2011) C. Gutierrez-Merino et al.   CURRENT MEDICINAL CHEMISTRY

Effects ofGlycyrrhizae Radixon Repeated Restraint Stress-induced Neurochemical and Behavioral Responses

(2011) Hyun-Jung Park et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Chronic Stress-induced Hippocampal Vulnerability: The Glucocorticoid Vulnerability Hypothesis

(2011) Cheryl D. Conrad   REVIEWS IN THE NEUROSCIENCES

LPS-induced indoleamine 2,3-dioxygenase is regulated in an interferon-γ-independent manner by a JNK signaling pathway in primary murine microglia

(2009) Yunxia Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin

(2009) Pamela Maher   Genes and Nutrition

Induction of IDO by Bacille Calmette-Guerin Is Responsible for Development of Murine Depressive-Like Behavior

(2009) J. C. O'Connor et al.   JOURNAL OF IMMUNOLOGY

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

A multifactorial developmental model for the etiology of Major Depression in a population-based sample

(2008) Louise Sjöholm et al.   JOURNAL OF AFFECTIVE DISORDERS

Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice

(2008) J C O'Connor et al.   MOLECULAR PSYCHIATRY

Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide

(2007) Y. Huang et al.   NEUROBIOLOGY OF AGING