Sodium Phenylbutyrate and Edaravone Abrogate Chronic Restraint Stress-Induced Behavioral Deficits: Implication of Oxido-Nitrosative, Endoplasmic Reticulum Stress Cascade, and Neuroinflammation

Honokiol abrogates chronic restraint stress-induced cognitive impairment and depressive-like behaviour by blocking endoplasmic reticulum stress in the hippocampus of mice

(2016) Ashok Jangra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Edaravone abrogates LPS-induced behavioral anomalies, neuroinflammation and PARP-1

(2016) Chandra Shaker Sriram et al.   PHYSIOLOGY & BEHAVIOR

Lasting downregulation of the lipid peroxidation enzymes in the prefrontal cortex of mice susceptible to stress-induced anhedonia

(2015) Brandon H. Cline et al.   BEHAVIOURAL BRAIN RESEARCH

Flupirtine attenuates chronic restraint stress-induced cognitive deficits and hippocampal apoptosis in male mice

(2015) Pengcheng Huang et al.   BEHAVIOURAL BRAIN RESEARCH

The dynamic changes of endoplasmic reticulum stress pathway markers GRP78 and CHOP in the hippocampus of diabetic mice

(2015) Yongmei Zhao et al.   BRAIN RESEARCH BULLETIN

Mangiferin ameliorates aluminium chloride-induced cognitive dysfunction via alleviation of hippocampal oxido-nitrosative stress, proinflammatory cytokines and acetylcholinesterase level

(2015) Prajapati Kasbe et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice

(2015) Chandra Shaker Sriram et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

7-Fluoro-1,3-diphenylisoquinoline-1-amine abolishes depressive-like behavior and prefrontal cortical oxidative damage induced by acute restraint stress in mice

(2015) Ana Paula Pesarico et al.   PHYSIOLOGY & BEHAVIOR

Honokiol abrogates lipopolysaccharide-induced depressive like behavior by impeding neuroinflammation and oxido-nitrosative stress in mice

(2014) Kunjbihari Sulakhiya et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effect of mangiferin against lipopolysaccharide-induced depressive and anxiety-like behaviour in mice

(2014) Ashok Jangra et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A longitudinal study of stress-induced hippocampal volume changes in mice that are susceptible or resilient to chronic social defeat

(2014) Yiu Chung Tse et al.   HIPPOCAMPUS

Hippocampal synaptic plasticity, spatial memory and anxiety

(2014) David M. Bannerman et al.   NATURE REVIEWS NEUROSCIENCE

Reversal of neurobehavioral and neurochemical alterations in STZ-induced diabetic rats by FeTMPyP, a peroxynitrite decomposition catalyst and 1,5-Isoquinolinediol a poly(ADP-ribose) polymerase inhibitor

(2014) Ashok Jangra et al.   NEUROLOGICAL RESEARCH

Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism

(2014) Kazuhiro Takuma et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Endoplasmic reticulum stress is involved in restraint stress-induced hippocampal apoptosis and cognitive impairments in rats

(2014) Yue Zhang et al.   PHYSIOLOGY & BEHAVIOR

Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

(2014) Francesca Calabrese et al.   Frontiers in Cellular Neuroscience

A Molecular Web: Endoplasmic Reticulum Stress, Inflammation, and Oxidative Stress

(2014) Namrata Chaudhari et al.   Frontiers in Cellular Neuroscience

Protective effects of luteolin on cognitive impairments induced by psychological stress in mice

(2013) Yi Liu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Effects of chronic social defeat stress on behaviour, endoplasmic reticulum proteins and choline acetyltransferase in adolescent mice

(2013) Guang-Biao Huang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Sodium Phenylbutyrate Enhances Astrocytic Neurotrophin Synthesis via Protein Kinase C (PKC)-mediated Activation of cAMP-response Element-binding Protein (CREB)

(2013) Grant T. Corbett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Psychological stress, cocaine and natural reward each induce endoplasmic reticulum stress genes in rat brain

(2013) A.A. Pavlovsky et al.   NEUROSCIENCE

Edaravone alleviates hypoxia-acidosis/reoxygenation-induced neuronal injury by activating ERK1/2

(2013) Guibin Wang et al.   NEUROSCIENCE LETTERS

Amelioration of diabetes-induced neurobehavioral and neurochemical changes by melatonin and nicotinamide: Implication of oxidative stress–PARP pathway

(2013) Ashok Jangra et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of chronic social defeat stress on behavior and choline acetyltransferase, 78-kDa glucose-regulated protein, and CCAAT/enhancer-binding protein (C/EBP) homologous protein in adult mice

(2013) Tong Zhao et al.   PSYCHOPHARMACOLOGY

Attenuation of axonal injury and oxidative stress by edaravone protects against cognitive impairments after traumatic brain injury

(2012) Manabu Ohta et al.   BRAIN RESEARCH

CHOP is a multifunctional transcription factor in the ER stress response

(2012) H. Nishitoh   JOURNAL OF BIOCHEMISTRY

Protective effects of nizofenone administration on the cognitive impairments induced by chronic restraint stress in mice

(2012) Yi Liu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease

(2012) Avik Roy et al.   PLoS One

Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex

(2012) Shuichi Chiba et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Edaravone Offers Neuroprotection in a Diabetic Stroke Model via Inhibition of Endoplasmic Reticulum Stress

(2011) Krishnamoorthy Srinivasan et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Lipopolysaccharide-Induced Sickness Behaviour Evaluated in Different Models of Anxiety and Innate Fear in Rats

(2011) Gabriel S. Bassi et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Sodium phenylbutyrate ameliorates focal cerebral ischemic/reperfusion injury associated with comorbid type 2 diabetes by reducing endoplasmic reticulum stress and DNA fragmentation

(2011) Krishnamoorthy Srinivasan et al.   BEHAVIOURAL BRAIN RESEARCH

Luteolin Shows an Antidepressant-Like Effect via Suppressing Endoplasmic Reticulum Stress

(2011) Mitsue Ishisaka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Edaravone alleviates delayed neuronal death and long-dated cognitive dysfunction of hippocampus after transient focal ischemia in Wistar rat brains

(2011) L. Jiao et al.   NEUROSCIENCE

Edaravone, a free radical scavenger, attenuates behavioral deficits following transient forebrain ischemia by inhibiting oxidative damage in gerbils

(2011) Feng Lu et al.   NEUROSCIENCE LETTERS

Glucocorticoid Generates ROS to Induce Oxidative Injury in the Hippocampus, Leading to Impairment of Cognitive Function of Rats

(2010) Hiroya Sato et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

(2009) Miao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Edaravone Protects Against Apoptotic Neuronal Cell Death and Improves Cerebral Function After Traumatic Brain Injury in Rats

(2009) Tatsuki Itoh et al.   NEUROCHEMICAL RESEARCH

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons

(2008) Wen Ji Yuan et al.   BMC NEUROSCIENCE

Aberrant endoplasmic reticulum stress response in lymphoblastoid cells from patients with bipolar disorder

(2008) Akiko Hayashi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Stress as a neuroinflammatory condition in brain: Damaging and protective mechanisms

(2008) Borja García-Bueno et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS