Adenylate Kinase: A Ubiquitous Enzyme Correlated with Medical Conditions

Repairing Mitochondrial Dysfunction in Disease

(2018) Vincenzo Sorrentino et al.   Annual Review of Pharmacology and Toxicology

Cardiovascular biomarkers in clinical studies of type 2 diabetes

(2018) Maria P. A. Baldassarre et al.   DIABETES OBESITY & METABOLISM

Homozygous missense mutation L673P in adenylate kinase 7 (AK7) leads to primary male infertility and multiple morphological anomalies of the flagella but not to primary ciliary dyskinesia

(2018) Patrick Lorès et al.   HUMAN MOLECULAR GENETICS

Development of a Novel Hygiene Monitoring System Based on the Detection of Total Adenylate (ATP+ADP+AMP)

(2018) MIKIO BAKKE et al.   JOURNAL OF FOOD PROTECTION

Molecular Docking Evaluation of (E)-5-arylidene-2-thioxothiazolidin-4-one Derivatives as Selective Bacterial Adenylate Kinase Inhibitors

(2018) Mihaela Ionescu et al.   MOLECULES

Focusing on mitochondrial form and function

(2018)   NATURE CELL BIOLOGY

Molecular mechanism of ATP versus GTP selectivity of adenylate kinase

(2018) Per Rogne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Absence of Tumor Necrosis Factor Supports Alternative Activation of Macrophages in the Liver after Infection with Leishmania major

(2018) Shanshan Hu et al.   Frontiers in Immunology

Characteristics in limbic encephalitis with anti–adenylate kinase 5 autoantibodies

(2017) Le-Duy Do et al.   NEUROLOGY

Immunization with recombinant schistosome adenylate kinase 1 partially protects mice against Schistosoma japonicum infection

(2017) Yanru Gao et al.   PARASITOLOGY RESEARCH

Fine structure of conformational ensembles in adenylate kinase

(2017) Yujing Wang et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy

(2017) Robert W. Myers et al.   SCIENCE

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

AMPK as a Therapeutic Target for Treating Metabolic Diseases

(2017) Emily A. Day et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Metabolism-Centric Overview of the Pathogenesis of Alzheimer's Disease

(2017) Somang Kang et al.   YONSEI MEDICAL JOURNAL

Disrupting glucose-6-phosphate isomerase fully suppresses the “Warburg effect” and activates OXPHOS with minimal impact on tumor growth except in hypoxia

(2017) Monique Cunha de Padua et al.   Oncotarget

Schistosomiasis Japonica Control in Domestic Animals: Progress and Experiences in China

(2017) Zhiguo Cao et al.   Frontiers in Microbiology

Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition

(2017) Eoon Hye Ji et al.   Journal of Cancer

Limb girdle myasthenia with digenic RAPSN and a novel disease gene AK9 mutations

(2016) Ching-Wan Lam et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

European Respiratory Society guidelines for the diagnosis of primary ciliary dyskinesia

(2016) Jane S. Lucas et al.   EUROPEAN RESPIRATORY JOURNAL

Modulation of anti-cancer drug sensitivity through the regulation of mitochondrial activity by adenylate kinase 4

(2016) Koichi Fujisawa et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Adenylate kinase: a novel antigen for immunodiagnosis and subunit vaccine against tuberculosis

(2016) Yangjiong Xiao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Deregulation of ocular nucleotide homeostasis in patients with diabetic retinopathy

(2016) Sirpa Loukovaara et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis

(2015) Adeline S.L. Ng et al.   JOURNAL OF NEUROIMMUNOLOGY

Purine metabolism gene deregulation in Parkinson's disease

(2015) Paula Garcia-Esparcia et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

(2015) E Six et al.   Cell Death & Disease

Energetics and Structural Characterization of the large-scale Functional Motion of Adenylate Kinase

(2015) Elena Formoso et al.   Scientific Reports

Mitochondria as signaling organelles

(2014) Navdeep S Chandel   BMC BIOLOGY

Congenital myasthenic syndromes and the neuromuscular junction

(2014) Pedro M. Rodríguez Cruz et al.   CURRENT OPINION IN NEUROLOGY

Purines in the eye: Recent evidence for the physiological and pathological role of purines in the RPE, retinal neurons, astrocytes, Müller cells, lens, trabecular meshwork, cornea and lacrimal gland

(2014) Julie Sanderson et al.   EXPERIMENTAL EYE RESEARCH

The many isoforms of human adenylate kinases

(2014) Christakis Panayiotou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Metabolic requirements for the maintenance of self-renewing stem cells

(2014) Keisuke Ito et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Isoprostanes and Neuroprostanes as Biomarkers of Oxidative Stress in Neurodegenerative Diseases

(2014) Elżbieta Miller et al.   Oxidative Medicine and Cellular Longevity

Uridine Affects Liver Protein Glycosylation, Insulin Signaling, and Heme Biosynthesis

(2014) Yasuyo Urasaki et al.   PLoS One

A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels

(2014) Nathan J. Lanning et al.   Cell Reports

Adenosine, adenosine receptors and glaucoma: An updated overview

(2013) Yisheng Zhong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Immunomodulation by helminth parasites: Defining mechanisms and mediators

(2013) Henry J. McSorley et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The human adenylate kinase 9 is a nucleoside mono- and diphosphate kinase

(2013) Marjan Amiri et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Comparative analysis of some aspects of mitochondrial metabolism in differentiated and undifferentiated neuroblastoma cells

(2013) Aleksandr Klepinin et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Deciphering the Catalysis-Associated Conformational Changes of Human Adenylate Kinase 1 with Single-Molecule Spectroscopy

(2013) Chien Y. Lin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Dynamic Increase in Extracellular ATP Accelerates Photoreceptor Cell Apoptosis via Ligation of P2RX7 in Subretinal Hemorrhage

(2013) Shoji Notomi et al.   PLoS One

Ak1 genetic polymorphism and season of conception

(2012) F. Gloria-Bottini et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Mitochondrial energy metabolism plays a critical role in the cardioprotection afforded by intermittent hypobaric hypoxia

(2012) Zhi-Hua Wang et al.   EXPERIMENTAL PHYSIOLOGY

Identification of a novel nuclear-localized adenylate kinase 6 from Arabidopsis thaliana as an essential stem growth factor

(2012) Xue Feng et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

hCINAP is an atypical mammalian nuclear adenylate kinase with an ATPase motif: Structural and functional studies

(2011) Christina E. Drakou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

AMP kinase: the missing link between type 2 diabetes and neurodegenerative diseases?

(2011) Mohamed Kodiha et al.   TRENDS IN MOLECULAR MEDICINE

The characterization of human adenylate kinases 7 and 8 demonstrates differences in kinetic parameters and structural organization among the family of adenylate kinase isoenzymes

(2010) Christakis Panayiotou et al.   BIOCHEMICAL JOURNAL

Adenylate Kinase 2 Links Mitochondrial Energy Metabolism to the Induction of the Unfolded Protein Response

(2010) Alison Burkart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Noncooperative Folding of Subdomains in Adenylate Kinase†

(2009) Louise Rundqvist et al.   BIOCHEMISTRY

Adenylate Kinase and AMP Signaling Networks: Metabolic Monitoring, Signal Communication and Body Energy Sensing

(2009) Petras Dzeja et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Helminth immunoregulation: The role of parasite secreted proteins in modulating host immunity

(2009) James P. Hewitson et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

RNAi screening: tips and techniques

(2009) Sonia Sharma et al.   NATURE IMMUNOLOGY

Congenital neutropenia

(2009) C. Klein   Hematology-American Society of Hematology Education Program

Mutation of Murine Adenylate Kinase 7 Underlies a Primary Ciliary Dyskinesia Phenotype

(2008) Angeles Fernandez-Gonzalez et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion

(2008) Rujuan Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase

(2008) Rujuan Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Modulation of Cell Motility by Spatial Repositioning of Enzymatic ATP/ADP Exchange Capacity

(2008) Remco van Horssen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2

(2008) Ulrich Pannicke et al.   NATURE GENETICS