Ex vivo treatment of prostate tumor tissue recapitulates in vivo therapy response

A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening

(2018) Michael L. Beshiri et al.   CLINICAL CANCER RESEARCH

Gallium-68 HBED-CC-PSMA Positron Emission Tomography/Magnetic Resonance Imaging for Prostate Fusion Biopsy

(2018) Kay M. Westenfelder et al.   Clinical Genitourinary Cancer

A patient-derived explant (PDE) model of hormone-dependent cancer

(2018) Margaret M. Centenera et al.   Molecular Oncology

Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient-derived xenograft (PDX) models

(2018) Nora M. Navone et al.   PROSTATE

An ex vivo Tissue Culture Model for the Assessment of Individualized Drug Responses in Prostate and Bladder Cancer

(2018) Arjanneke F. van de Merbel et al.   Frontiers in Oncology

PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors

(2017) Leslie A. Parsels et al.   MOLECULAR CANCER RESEARCH

PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma

(2017) V Colicchia et al.   ONCOGENE

Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project

(2017) Ronald de Hoogt et al.   Scientific Data

Tumor slice culture system to assess drug response of primary breast cancer

(2016) Kishan A. T. Naipal et al.   BMC CANCER

Organotypic slice cultures of human gastric and esophagogastric junction cancer

(2016) Justus Koerfer et al.   Cancer Medicine

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

(2015) Hui Gao et al.   NATURE MEDICINE

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

(2015) Joaquin Mateo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices

(2015) Emma J. Davies et al.   Scientific Reports

Three-dimensional models of cancer for pharmacology and cancer cell biology: Capturing tumor complexity in vitro/ex vivo

(2014) John A. Hickman et al.   Biotechnology Journal

Cancer Cell Lines for Drug Discovery and Development

(2014) J. L. Wilding et al.   CANCER RESEARCH

Applicability of rat precision-cut lung slices in evaluating nanomaterial cytotoxicity, apoptosis, oxidative stress, and inflammation

(2014) Ursula G. Sauer et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Slice cultures from head and neck squamous cell carcinoma: a novel test system for drug susceptibility and mechanisms of resistance

(2013) M M Gerlach et al.   BRITISH JOURNAL OF CANCER

Low systemic testosterone levels induce androgen maintenance in benign rat prostate tissue

(2013) Ye Zhou et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Optimization and comprehensive characterization of a faithful tissue culture model of the benign and malignant human prostate

(2013) Sophia Lisette Maund et al.   LABORATORY INVESTIGATION

Ex vivo culture of human prostate tissue and drug development

(2013) Margaret M. Centenera et al.   Nature Reviews Urology

Organotypic slice cultures of human glioblastoma reveal different susceptibilities to treatments

(2013) Felicitas Merz et al.   NEURO-ONCOLOGY

Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer

(2013) Javier Guerrero et al.   PROSTATE

Evidence for Efficacy of New Hsp90 Inhibitors Revealed by Ex Vivo Culture of Human Prostate Tumors

(2012) M. M. Centenera et al.   CLINICAL CANCER RESEARCH

The practicalities of using tissue slices as preclinical organotypic breast cancer models

(2012) Deborah L Holliday et al.   JOURNAL OF CLINICAL PATHOLOGY

Dual Roles of PARP-1 Promote Cancer Growth and Progression

(2012) M. J. Schiewer et al.   Cancer Discovery

Validation of organotypical hippocampal slice cultures as an ex vivo model of brain ischemia: different roles of NMDA receptors in cell death signalling after exposure to NMDA or oxygen and glucose deprivation

(2011) Hanna Ahlgren et al.   CELL AND TISSUE RESEARCH

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

(2010) Inge A M de Graaf et al.   Nature Protocols

Bcl-2 Modulation to Activate Apoptosis in Prostate Cancer

(2009) K. Bray et al.   MOLECULAR CANCER RESEARCH

A novel tissue-slice culture model for non-malignant human prostate

(2008) M. Bläuer et al.   CELL AND TISSUE RESEARCH