Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor

Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin

(2018) Jaimie Chang et al.   FASEB JOURNAL

Resolvins suppress tumor growth and enhance cancer therapy

(2017) Megan L. Sulciner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

COX-2/sEH Dual Inhibitor PTUPB Potentiates the Antitumor Efficacy of Cisplatin

(2017) Fuli Wang et al.   MOLECULAR CANCER THERAPEUTICS

Stress-inducible geneAtf3in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis

(2017) Yi Seok Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

(2017) George S. Karagiannis et al.   Science Translational Medicine

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm

(2017) Patrick Younan et al.   mBio

Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era

(2017) Edward M. Behrens et al.   Arthritis & Rheumatology

Platelet-activating factor (PAF) receptor as a promising target for cancer cell repopulation after radiotherapy

(2017) I A da Silva-Jr et al.   Oncogenesis

PGE2 induced in and released by dying cells functions as an inhibitory DAMP

(2016) Sho Hangai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CYP450-derived oxylipins mediate inflammatory resolution

(2016) Derek W. Gilroy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer

(2015) C. S. Milagre et al.   CANCER RESEARCH

Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma

(2015) Catriona A. Ford et al.   CURRENT BIOLOGY

An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics

(2015) Daniel M. Reed et al.   FASEB JOURNAL

Evidence for induction of a tumor metastasis-receptive microenvironment for ovarian cancer cells in bone marrow and other organs as an unwanted and underestimated side effect of chemotherapy/radiotherapy

(2015) Pranesh M Gunjal et al.   Journal of Ovarian Research

Paclitaxel Therapy Promotes Breast Cancer Metastasis in a TLR4-Dependent Manner

(2014) L. Volk-Draper et al.   CANCER RESEARCH

Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution

(2014) Jamie C. Stanford et al.   JOURNAL OF CLINICAL INVESTIGATION

Bioactive Lipids, LPC and LPA, Are Novel Prometastatic Factors and Their Tissue Levels Increase in Response to Radio/Chemotherapy

(2014) Gabriela Schneider et al.   MOLECULAR CANCER RESEARCH

Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance

(2014) Antonina V. Kurtova et al.   NATURE

Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis

(2014) G. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemotherapy-enhanced inflammation may lead to the failure of therapy and metastasis

(2014) Dinesh Vyas et al.   OncoTargets and Therapy

Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition

(2013) Benoît Thibault et al.   CANCER AND METASTASIS REVIEWS

A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors

(2013) Shahneen K. Sandhu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden

(2013) Khalid Abubaker et al.   Molecular Cancer

Bioactive Lipids S1P and C1P Are Prometastatic Factors in Human Rhabdomyosarcoma, and Their Tissue Levels Increase in Response to Radio/Chemotherapy

(2013) Gabriela Schneider et al.   MOLECULAR CANCER RESEARCH

Fatty Acid Metabolites in Rapidly Proliferating Breast Cancer

(2013) Joseph T. O’Flaherty et al.   PLoS One

Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn’s Disease?

(2013) Jonas Bystrom et al.   PLoS One

Cyclophosphamide Creates a Receptive Microenvironment for Prostate Cancer Skeletal Metastasis

(2012) S. I. Park et al.   CANCER RESEARCH

Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer

(2012) G. Rao et al.   CLINICAL CANCER RESEARCH

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

(2012) Jakob von Moltke et al.   NATURE

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome

(2011) Kristin A. D. Sauter et al.   CANCER BIOLOGY & THERAPY

Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase

(2011) Sung Hee Hwang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Conditioning for hematopoietic transplantation activates the complement cascade and induces a proteolytic environment in bone marrow: a novel role for bioactive lipids and soluble C5b-C9 as homing factors

(2011) C H Kim et al.   LEUKEMIA

Caspase 3–mediated stimulation of tumor cell repopulation during cancer radiotherapy

(2011) Qian Huang et al.   NATURE MEDICINE

Cisplatin Treatment Induces a Transient Increase in Tumorigenic Potential Associated with High Interleukin-6 Expression in Head and Neck Squamous Cell Carcinoma

(2010) Kim J. Poth et al.   MOLECULAR CANCER THERAPEUTICS

Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

(2009) Jun Yang et al.   ANALYTICAL CHEMISTRY

Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model

(2009) Jun-Yan Liu et al.   BIOCHEMICAL PHARMACOLOGY

Soluble epoxide hydrolase as a therapeutic target for cardiovascular diseases

(2009) John D. Imig et al.   NATURE REVIEWS DRUG DISCOVERY

Decreased IL-1 RA concentration in ascites is associated with a significant improvement in overall survival in ovarian cancer

(2008) A. Mustea et al.   CYTOKINE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Epithelial–stromal interaction increases cell proliferation, survival and tumorigenicity in a mouse model of human epithelial ovarian cancer

(2007) James Greenaway et al.   GYNECOLOGIC ONCOLOGY