TBX5 drives Scn5a expression to regulate cardiac conduction system function

T-box transcription factor TBX3 reprogrammes mature cardiac myocytes into pacemaker-like cells

(2012) Martijn L. Bakker et al.   CARDIOVASCULAR RESEARCH

Biology of cardiac sodium channel Nav1.5 expression

(2011) M. B. Rook et al.   CARDIOVASCULAR RESEARCH

Molecular Analysis of Patterning of Conduction Tissues in the Developing Human Heart

(2011) Aleksander Sizarov et al.   Circulation-Arrhythmia and Electrophysiology

Inducible recombination in the cardiac conduction system of minK: CreERT2 BAC transgenic mice

(2011) David E. Arnolds et al.   GENESIS

Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis

(2011) D. U. Frank et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

(2011) A. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Association Studies of the PR Interval in African Americans

(2011) J. Gustav Smith et al.   PLoS Genetics

The Fifteen Years of Discoveries That Shaped Molecular Electrophysiology

(2010) Silvia G. Priori   CIRCULATION RESEARCH

Contactin-2 Expression in the Cardiac Purkinje Fiber Network

(2010) Benedetta A. Pallante et al.   Circulation-Arrhythmia and Electrophysiology

Genome-wide discovery of human heart enhancers

(2010) L. Narlikar et al.   GENOME RESEARCH

ChIP-Seq identification of weakly conserved heart enhancers

(2010) Matthew J Blow et al.   NATURE GENETICS

Several common variants modulate heart rate, PR interval and QRS duration

(2010) Hilma Holm et al.   NATURE GENETICS

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

(2010) Nona Sotoodehnia et al.   NATURE GENETICS

Genome-wide association study of PR interval

(2010) Arne Pfeufer et al.   NATURE GENETICS

Genetic variation in SCN10A influences cardiac conduction

(2010) John C Chambers et al.   NATURE GENETICS

Variable Nav1.5 Protein Expression from the Wild-Type Allele Correlates with the Penetrance of Cardiac Conduction Disease in the Scn5a+/− Mouse Model

(2010) Anne-Laure Leoni et al.   PLoS One

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

(2009) C. A. Remme et al.   BASIC RESEARCH IN CARDIOLOGY

Specification of the Cardiac Conduction System by Transcription Factors

(2009) Cathy J. Hatcher et al.   CIRCULATION RESEARCH

sonic hedgehog is required in pulmonary endoderm for atrial septation

(2009) A. D. Hoffmann et al.   DEVELOPMENT

Role of the His-Purkinje system in the genesis of cardiac arrhythmia

(2009) Melvin M. Scheinman   HEART RHYTHM

Genome-wide association study of electrocardiographic conduction measures in an isolated founder population: Kosrae

(2009) J. Gustav Smith et al.   HEART RHYTHM

Long-term Outcomes in Individuals With Prolonged PR Interval or First-Degree Atrioventricular Block

(2009) Susan Cheng   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

(2009) JACOB TFELT-HANSEN et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Tissue distribution and subcellular localization of the cardiac sodium channel during mouse heart development

(2008) Jorge N. Domínguez et al.   CARDIOVASCULAR RESEARCH

Perinatal Loss of Nkx2-5 Results in Rapid Conduction and Contraction Defects

(2008) Laura E. Briggs et al.   CIRCULATION RESEARCH

Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin

(2008) Fang Liu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY