Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer’s disease amyloidosis

What Happens with the Circuit in Alzheimer's Disease in Mice and Humans?

(2018) Benedikt Zott et al.   Annual Review of Neuroscience

Hippocampal GABAergic Inhibitory Interneurons

(2017) Kenneth A. Pelkey et al.   PHYSIOLOGICAL REVIEWS

Type 2 diabetes alters hippocampal gamma oscillations: A potential mechanism behind impaired cognition

(2017) Grazyna Lietzau et al.   PSYCHONEUROENDOCRINOLOGY

APP modulates KCC2 expression and function in hippocampal GABAergic inhibition

(2017) Ming Chen et al.   eLife

Biphasic Alteration of the Inhibitory Synapse Scaffold Protein Gephyrin in Early and Late Stages of an Alzheimer Disease Model

(2016) Eva Kiss et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuronal Firing Rate Homeostasis Is Inhibited by Sleep and Promoted by Wake

(2016) Keith B. Hengen et al.   CELL

Identification of Parvalbumin Interneurons as Cellular Substrate of Fear Memory Persistence

(2016) Gürsel Çalışkan et al.   CEREBRAL CORTEX

Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses

(2016) Nuno J. Machado et al.   MOLECULAR NEUROBIOLOGY

Network abnormalities and interneuron dysfunction in Alzheimer disease

(2016) Jorge J. Palop et al.   NATURE REVIEWS NEUROSCIENCE

Early synaptic deficits in the APP/PS1 mouse model of Alzheimer’s disease involve neuronal adenosine A2A receptors

(2016) Silvia Viana da Silva et al.   Nature Communications

Hippocampal sharp-wave ripples in waking and sleeping states

(2015) Demetris K Roumis et al.   CURRENT OPINION IN NEUROBIOLOGY

Vulnerability of calbindin, calretinin and parvalbumin in a transgenic/knock-in APPswe/PS1dE9 mouse model of Alzheimer disease together with disruption of hippocampal neurogenesis

(2015) Ester Verdaguer et al.   EXPERIMENTAL GERONTOLOGY

Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia

(2015) Jonathan Witton et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

(2015) J A Brown et al.   MOLECULAR PSYCHIATRY

No evidence for role of extracellular choline-acetyltransferase in generation of gamma oscillations in rat hippocampal slices in vitro

(2015) J.O. Hollnagel et al.   NEUROSCIENCE

Caffeine acts through neuronal adenosine A2Areceptors to prevent mood and memory dysfunction triggered by chronic stress

(2015) Manuella P. Kaster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease

(2015) Marilia S. Albuquerque et al.   Frontiers in Aging Neuroscience

Early alterations in energy metabolism in the hippocampus of APPswe/PS1dE9 mouse model of Alzheimer's disease

(2014) Ignacio Pedrós et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Quantitative ultrastructural analysis of basket and axo-axonic cell terminals in the mouse hippocampus

(2014) Virág T. Takács et al.   Brain Structure & Function

Mechanisms of Sharp Wave Initiation and Ripple Generation

(2014) D. Schlingloff et al.   JOURNAL OF NEUROSCIENCE

GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

(2014) Seonmi Jo et al.   NATURE MEDICINE

Pyramidal Cell-Interneuron Interactions Underlie Hippocampal Ripple Oscillations

(2014) Eran Stark et al.   NEURON

Activity-dependent inhibitory synapse remodeling through gephyrin phosphorylation

(2014) Carmen E. Flores et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulating excitation through plasticity at inhibitory synapses

(2014) Vivien Chevaleyre et al.   Frontiers in Cellular Neuroscience

Quantitative assessment of CA1 local circuits: Knowledge base for interneuron-pyramidal cell connectivity

(2013) Marianne J. Bezaire et al.   HIPPOCAMPUS

Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning

(2013) Flavio Donato et al.   NATURE

Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis

(2013) Helen S. Bateup et al.   NEURON

Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease

(2013) Paula M. Canas et al.   NEUROPHARMACOLOGY

Mechanisms of Gamma Oscillations

(2012) György Buzsáki et al.   Annual Review of Neuroscience

Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model

(2012) Laure Verret et al.   CELL

Phosphorylation of Gephyrin in Hippocampal Neurons by Cyclin-dependent Kinase CDK5 at Ser-270 Is Dependent on Collybistin

(2012) Jochen Kuhse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elimination of Inhibitory Synapses Is a Major Component of Adult Ocular Dominance Plasticity

(2012) Daniëlle van Versendaal et al.   NEURON

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Critical role of soluble amyloid-  for early hippocampal hyperactivity in a mouse model of Alzheimer's disease

(2012) M. A. Busche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitory Synapse Dynamics: Coordinated Presynaptic and Postsynaptic Mobility and the Major Contribution of Recycled Vesicles to New Synapse Formation

(2011) F. A. Dobie et al.   JOURNAL OF NEUROSCIENCE

A disinhibitory microcircuit for associative fear learning in the auditory cortex

(2011) Johannes J. Letzkus et al.   NATURE

Synaptic dysfunction in hippocampus of transgenic mouse models of Alzheimer's disease: A multi-electrode array study

(2011) Seon-Ah Chong et al.   NEUROBIOLOGY OF DISEASE

GABAergic interneuron origin of schizophrenia pathophysiology

(2011) Kazu Nakazawa et al.   NEUROPHARMACOLOGY

Cellular correlate of assembly formation in oscillating hippocampal networks in vitro

(2011) F. Bahner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer’s disease

(2010) Hisaaki Takahashi et al.   Brain Structure & Function

Two distinct mechanisms target GAD67 to vesicular pathways and presynaptic clusters

(2010) Jamil Kanaani et al.   JOURNAL OF CELL BIOLOGY

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Early onset amyloid lesions lead to severe neuritic abnormalities and local, but not global neuron loss in APPPS1 transgenic mice

(2010) Niels J. Rupp et al.   NEUROBIOLOGY OF AGING

Synaptic Plasticity in the Hippocampus of a APP/PS1 Mouse Model of Alzheimer's Disease Is Impaired in Old but Not Young Mice

(2010) Simon Gengler et al.   PLoS One

Selective translocation of Ca2+/calmodulin protein kinase II  (CaMKII ) to inhibitory synapses

(2010) K. C. Marsden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease

(2009) A. Auffret et al.   JOURNAL OF NEUROSCIENCE

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

 -Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer's Disease

(2009) L. Serneels et al.   SCIENCE

Opening of the blood-brain barrier during isoflurane anaesthesia

(2008) Samuel Tétrault et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Sustained increase in hippocampal sharp-wave ripple activity during slow-wave sleep after learning

(2008) O. Eschenko et al.   LEARNING & MEMORY

Subfield and layer-specific depletion in calbindin-D28K, calretinin and parvalbumin immunoreactivity in the dentate gyrus of amyloid precursor protein/presenilin 1 transgenic mice

(2008) M. Popović et al.   NEUROSCIENCE

Neuronal Diversity and Temporal Dynamics: The Unity of Hippocampal Circuit Operations

(2008) T. Klausberger et al.   SCIENCE