Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts

Replication fork dynamics and the DNA damage response

(2012) Rebecca M. Jones et al.   BIOCHEMICAL JOURNAL

Timeless preserves telomere length by promoting efficient DNA replication through human telomeres

(2012) Adam R. Leman et al.   CELL CYCLE

Mechanisms of replication fork protection: a safeguard for genome stability

(2012) Alessia Errico et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase

(2012) N. Sabouri et al.   GENES & DEVELOPMENT

Altered Replication in Human Cells Promotes DMPK (CTG)n {middle dot} (CAG)n Repeat Instability

(2012) G. Liu et al.   MOLECULAR AND CELLULAR BIOLOGY

Replisome Stability at Defective DNA Replication Forks Is Independent of S Phase Checkpoint Kinases

(2012) Giacomo De Piccoli et al.   MOLECULAR CELL

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA

(2012) J. Speroni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATR signalling: more than meeting at the fork

(2011) Edward A. Nam et al.   BIOCHEMICAL JOURNAL

Claspin and Chk1 regulate replication fork stability by different mechanisms

(2011) Jennifer Scorah et al.   CELL CYCLE

The many facets of the Tim-Tipin protein families’ roles in chromosome biology

(2011) Ramsay J. McFarlane et al.   CELL CYCLE

Characterization of functional domains in human Claspin

(2011) Özdemirhan Serçin et al.   CELL CYCLE

Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts

(2011) Stephanie L. Smith-Roe et al.   CELL CYCLE

The Replisome Pausing Factor Timeless Is Required for Episomal Maintenance of Latent Epstein-Barr Virus

(2011) J. Dheekollu et al.   JOURNAL OF VIROLOGY

Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication

(2011) C. S. Sorensen et al.   NUCLEIC ACIDS RESEARCH

Timeless Links Replication Termination to Mitotic Kinase Activation

(2011) Jayaraju Dheekollu et al.   PLoS One

Multiple Functions of the S-Phase Checkpoint Mediator

(2010) Katsunori TANAKA   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites

(2010) Martin F. Arlt et al.   DNA REPAIR

Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

(2010) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion

(2010) A. R. Leman et al.   JOURNAL OF CELL SCIENCE

Pathways of mammalian replication fork restart

(2010) Eva Petermann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chk1 promotes replication fork progression by controlling replication initiation

(2010) E. Petermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human intra-S checkpoint response to UVC-induced DNA damage

(2009) William K. Kaufmann   CARCINOGENESIS

Claspin inhibition leads to fragile site expression

(2009) Maria Luisa Focarelli et al.   GENES CHROMOSOMES & CANCER

Replisome progression complex links DNA replication to sister chromatid cohesion inXenopusegg extracts

(2009) Hiroshi Tanaka et al.   GENES TO CELLS

Csm3, Tof1, and Mrc1 Form a Heterotrimeric Mediator Complex That Associates with DNA Replication Forks

(2009) Masashige Bando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tim–Tipin dysfunction creates an indispensible reliance on the ATR–Chk1 pathway for continued DNA synthesis

(2009) Kevin D. Smith et al.   JOURNAL OF CELL BIOLOGY

Checkpoint responses to unusual structures formed by DNA repeats

(2009) Irina Voineagu et al.   MOLECULAR CARCINOGENESIS

Chk1 and Claspin potentiate PCNA ubiquitination

(2008) X. H. Yang et al.   GENES & DEVELOPMENT

Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication

(2008) Karen A. Urtishak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Claspin Promotes Normal Replication Fork Rates in Human Cells

(2008) Eva Petermann et al.   MOLECULAR BIOLOGY OF THE CELL

Experimental validation of the importance of seed complement frequency to siRNA specificity

(2008) E. M. Anderson et al.   RNA