Transgenic zebrafish models reveal distinct molecular mechanisms for cataract-linked αA-crystallin mutants

Probing the changes in gene expression due to α-crystallin mutations in mouse models of hereditary human cataract

(2018) Usha P. Andley et al.   PLoS One

Loss of αB-crystallin function in zebrafish reveals critical roles in the development of the lens and stress resistance of the heart

(2017) Sanjay Mishra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of αB-crystallin: Role in stress, aging and patho-physiological conditions

(2016) Raman Bakthisaran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Small Heat-shock Proteins Prevent α-Synuclein Aggregation via Transient Interactions and Their Efficacy Is Affected by the Rate of Aggregation

(2016) Dezerae Cox et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of Cataract-linked γ-Crystallin Variants in Zebrafish Reveals a Proteostasis Network That Senses Protein Stability

(2016) Shu-Yu Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A conserved role of αA-crystallin in the development of the zebrafish embryonic lens

(2015) Ping Zou et al.   EXPERIMENTAL EYE RESEARCH

Cell biological roles of αB-crystallin

(2014) Wilbert C. Boelens   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Loss of the small heat shock protein αA-crystallin does not lead to detectable defects in early zebrafish lens development

(2013) Mason Posner et al.   EXPERIMENTAL EYE RESEARCH

Regulated structural transitions unleash the chaperone activity of  B-crystallin

(2013) J. Peschek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins

(2012) Sanjay Mishra et al.   FEBS LETTERS

sHSP in the eye lens: Crystallin mutations, cataract and proteostasis

(2012) Alice R. Clark et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Integrin α5/fibronectin1 and focal adhesion kinase are required for lens fiber morphogenesis in zebrafish

(2012) Julie M. Hayes et al.   MOLECULAR BIOLOGY OF THE CELL

Cataract-Causing Defect of a Mutant γ-Crystallin Proceeds through an Aggregation Pathway Which Bypasses Recognition by the α-Crystallin Chaperone

(2012) Kate L. Moreau et al.   PLoS One

Quaternary structural parameters of the congenital cataract causing mutants of αA-crystallin

(2011) Rajshekhar Kore et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A Knock-In Mouse Model for the R120G Mutation of αB-Crystallin Recapitulates Human Hereditary Myopathy and Cataracts

(2011) Usha P. Andley et al.   PLoS One

Apoptosis: Its Functions and Control in the Ocular Lens

(2010) L. Zhang et al.   CURRENT MOLECULAR MEDICINE

The Cataract-Associated R14C Mutant of Human γD-Crystallin Shows a Variety of Intermolecular Disulfide Cross-Links: A Raman Spectroscopic Study,

(2009) Ajay Pande et al.   BIOCHEMISTRY

Structure and Mechanism of Protein Stability Sensors: Chaperone Activity of Small Heat Shock Proteins

(2009) Hassane S. Mchaourab et al.   BIOCHEMISTRY

Lens aging: Effects of crystallins

(2009) K. Krishna Sharma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Early lens development in the zebrafish: A three-dimensional time-lapse analysis

(2009) Teri M.S. Greiling et al.   DEVELOPMENTAL DYNAMICS

Disulfide cross-links in the interaction of a cataract-linked αA-crystallin mutant with βB1-crystallin

(2008) M. Satish Kumar et al.   FEBS LETTERS

Small Heat Shock Protein Activity Is Regulated by Variable Oligomeric Substructure

(2008) Justin L. P. Benesch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Orientation of T4 Lysozyme Bound to the Small Heat Shock Protein α-Crystallin

(2007) Derek P. Claxton et al.   JOURNAL OF MOLECULAR BIOLOGY

Zebrafish: A model system for the study of eye genetics

(2007) J FADOOL et al.   PROGRESS IN RETINAL AND EYE RESEARCH