Metformin induces significant reduction of body weight, total cholesterol and LDL levels in the elderly – A meta-analysis

A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality

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Involuntary Weight Loss Secondary to Metformin Use in Elderly Adults

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Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus—the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial

(2016) Louise Lundby-Christensen et al.   BMJ Open

10. Older Adults: Table 10.1

(2015)   DIABETES CARE

Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012

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Metformin Ameliorates Hepatic Steatosis and Inflammation without Altering Adipose Phenotype in Diet-Induced Obesity

(2014) Shih-Lung Woo et al.   PLoS One

Effects of metformin on weight loss

(2014) Steven K. Malin et al.   Current Opinion in Endocrinology Diabetes and Obesity

Metformin: Do we finally have an anti-aging drug?

(2013) Vladimir N. Anisimov   CELL CYCLE

2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults

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Possible involvement of melanocortin-4-receptor and AMP-activated protein kinase in the interaction of glucagon-like peptide-1 and leptin on feeding in rats

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The effect of metformin on food intake and its potential role in hypothalamic regulation in obese diabetic rats

(2012) Wen-shan Lv et al.   BRAIN RESEARCH

Metformin slows down aging and extends life span of female SHR mice

(2011) Vladimir N. Anisimov et al.   CELL CYCLE

Long-term Effects of Metformin on Metabolism and Microvascular and Macrovascular Disease in Patients With Type 2 Diabetes Mellitus

(2009) Adriaan Kooy et al.   ARCHIVES OF INTERNAL MEDICINE

Comparison of vildagliptin and metformin monotherapy in elderly patients with type 2 diabetes: a 24-week, double-blind, randomized trial

(2009) A. Schweizer et al.   DIABETES OBESITY & METABOLISM

The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

(2009) Alessandro Liberati et al.   PLOS MEDICINE

Metformin, but not pioglitazone, decreases postchallenge plasma ghrelin levels in type 2 diabetic patients: a possible role in weight stability?

(2008) I. Kusaka et al.   DIABETES OBESITY & METABOLISM