Psoralidin Stimulates Expression of Immediate-Early Genes and Synapse Development in Primary Cortical Neurons

The higher osteoprotective activity of psoralidin in vivo than coumestrol is attributed by its presence of an isopentenyl group and through activated PI3K/Akt axis

(2018) Yuankun Zhai et al.   BIOMEDICINE & PHARMACOTHERAPY

Dietary Total Prenylflavonoids from the Fruits of Psoralea corylifolia L. Prevents Age-Related Cognitive Deficits and Down-Regulates Alzheimer’s Markers in SAMP8 Mice

(2018) Zhi-Jing Chen et al.   MOLECULES

Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons

(2018) Seojin Hwang et al.   NEUROTOXICOLOGY

Plasma pharmacokinetics and cerebral nuclei distribution of major constituents of Psoraleae fructus in rats after oral administration

(2018) Yan-Fang Yang et al.   PHYTOMEDICINE

Regulation of spine structural plasticity by Arc/Arg3.1

(2018) Thomas M. Newpher et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Psoralidin, a prenylated coumestan, as a novel anti-osteoporosis candidate to enhance bone formation of osteoblasts and decrease bone resorption of osteoclasts

(2017) Yuankun Zhai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Psoralidin suppresses osteoclastogenesis in BMMs and attenuates LPS-mediated osteolysis by inhibiting inflammatory cytokines

(2017) Lingbo Kong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Differential roles for Akt and mTORC1 in the hypertrophy of Pten mutant neurons, a cellular model of brain overgrowth disorders

(2017) Ina Nikolaeva et al.   NEUROSCIENCE

Dysfunction of NMDA receptors in Alzheimer’s disease

(2016) Yan Zhang et al.   NEUROLOGICAL SCIENCES

An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia

(2016) Darrick T Balu et al.   NEUROPSYCHOPHARMACOLOGY

Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells

(2016) Guowen Ren et al.   PHYTOMEDICINE

A PARP1-ERK2 synergism is required for the induction of LTP

(2016) L. Visochek et al.   Scientific Reports

Role of Immediate-Early Genes in Synaptic Plasticity and Neuronal Ensembles Underlying the Memory Trace

(2016) Keiichiro Minatohara et al.   Frontiers in Molecular Neuroscience

Glutamate affects dendritic morphology of neurons grown on compliant substrates

(2015) Michelle L. Previtera et al.   BIOTECHNOLOGY PROGRESS

Neuronal polarization

(2015) T. Takano et al.   DEVELOPMENT

Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes

(2015) Kazuyuki Fujihara et al.   NEUROPSYCHOPHARMACOLOGY

Activity-Dependent Bidirectional Regulation of GAD Expression in a Homeostatic Fashion Is Mediated by BDNF-Dependent and Independent Pathways

(2015) Yoko Hanno-Iijima et al.   PLoS One

Differential effect of psoralidin in enhancing apoptosis of colon cancer cells via nuclear factor-κB and B-cell lymphoma-2/B-cell lymphoma-2-associated X protein signaling pathways

(2015) ZHILIANG JIN et al.   Oncology Letters

Poly (ADP-ribose) in the pathogenesis of Parkinson's disease

(2014) Yunjong Lee et al.   BMB Reports

Reelin Induces Erk1/2 Signaling in Cortical Neurons Through a Non-canonical Pathway

(2014) Gum Hwa Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamate and its receptors in cancer

(2014) Andrzej Stepulak et al.   JOURNAL OF NEURAL TRANSMISSION

Psoralidin induces autophagy through ROS generation which inhibits the proliferation of human lung cancer A549 cells

(2014) Wenhui Hao et al.   PeerJ

Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells

(2013) S Suman et al.   BRITISH JOURNAL OF CANCER

Advantages of an antagonist: bicuculline and other GABA antagonists

(2013) Graham AR Johnston   BRITISH JOURNAL OF PHARMACOLOGY

Immediate-early gene activation by the MAPK pathways: what do and don't we know?

(2012) Amanda O'Donnell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

NMDA Receptor Hypofunction, Parvalbumin-Positive Neurons, and Cortical Gamma Oscillations in Schizophrenia

(2012) G. Gonzalez-Burgos et al.   SCHIZOPHRENIA BULLETIN

Psoralidin, a dual inhibitor of COX-2 and 5-LOX, regulates ionizing radiation (IR)-induced pulmonary inflammation

(2011) Hee Jung Yang et al.   BIOCHEMICAL PHARMACOLOGY

Assessment of the role of MAP kinase in mediating activity-dependent transcriptional activation of the immediate early gene Arc/Arg3.1 in the dentate gyrus in vivo

(2010) J. K. Chotiner et al.   LEARNING & MEMORY

A negative regulator of MAP kinase causes depressive behavior

(2010) Vanja Duric et al.   NATURE MEDICINE

Arc regulates spine morphology and maintains network stability in vivo

(2010) C. L. Peebles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain Region-Specific Gene Expression Activation Required for Reconsolidation and Extinction of Contextual Fear Memory

(2009) N. Mamiya et al.   JOURNAL OF NEUROSCIENCE

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Regulation of the NMDA receptor-mediated synaptic response by acetylcholinesterase inhibitors and its impairment in an animal model of Alzheimer's disease

(2007) Guojun Chen et al.   NEUROBIOLOGY OF AGING

Protein synthesis inhibition and memory: Formation vs amnesia

(2007) Paul E. Gold   NEUROBIOLOGY OF LEARNING AND MEMORY