Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structure-guided development of YEATS domain inhibitors by targeting π-π-π stacking
Authors
Keywords
-
Journal
Nature Chemical Biology
Volume 14, Issue 12, Pages 1140-1149
Publisher
Springer Nature America, Inc
Online
2018-10-24
DOI
10.1038/s41589-018-0144-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation
- (2017) Leah A. Gates et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- YEATS Domain—A Histone Acylation Reader in Health and Disease
- (2017) Dan Zhao et al. JOURNAL OF MOLECULAR BIOLOGY
- Transcription control by the ENL YEATS domain in acute leukaemia
- (2017) Michael A. Erb et al. NATURE
- ENL links histone acetylation to oncogenic gene expression in acute myeloid leukaemia
- (2017) Liling Wan et al. NATURE
- MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia
- (2017) Jon Kerry et al. Cell Reports
- The Cellular Thermal Shift Assay: A Novel Biophysical Assay for In Situ Drug Target Engagement and Mechanistic Biomarker Studies
- (2016) Daniel Martinez Molina et al. Annual Review of Pharmacology and Toxicology
- YEATS2 is a selective histone crotonylation reader
- (2016) Dan Zhao et al. CELL RESEARCH
- Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
- (2016) Yuanyuan Li et al. MOLECULAR CELL
- The Taf14 YEATS domain is a reader of histone crotonylation
- (2016) Forest H Andrews et al. Nature Chemical Biology
- Functional interdependence of BRD4 and DOT1L in MLL leukemia
- (2016) Omer Gilan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain
- (2016) Qiang Zhang et al. STRUCTURE
- Functional interdependence of BRD4 and DOT1L in MLL leukemia
- (2016) Omer Gilan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- BET bromodomain inhibitors in leukemia
- (2015) Faisal Basheer et al. EXPERIMENTAL HEMATOLOGY
- Probing the epigenome
- (2015) Andrea Huston et al. Nature Chemical Biology
- Developing diazirine-based chemical probes to identify histone modification ‘readers’ and ‘erasers’
- (2015) Tangpo Yang et al. Chemical Science
- MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours
- (2015) Elizabeth J. Perlman et al. Nature Communications
- Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential
- (2015) Aravinda Kuntimaddi et al. Cell Reports
- Enzyme Inhibitor Discovery by Activity-Based Protein Profiling
- (2014) Micah J. Niphakis et al. Annual Review of Biochemistry
- AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 Methylation
- (2014) Yuanyuan Li et al. CELL
- The cellular thermal shift assay for evaluating drug target interactions in cells
- (2014) Rozbeh Jafari et al. Nature Protocols
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- Writers and Readers of Histone Acetylation: Structure, Mechanism, and Inhibition
- (2014) R. Marmorstein et al. Cold Spring Harbor Perspectives in Biology
- Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach
- (2014) Xiucong Bao et al. eLife
- Readout of Epigenetic Modifications
- (2013) Dinshaw J. Patel et al. Annual Review of Biochemistry
- Chromatin proteins and modifications as drug targets
- (2013) Kristian Helin et al. NATURE
- Quantitative Chemical Proteomics Approach To Identify Post-translational Modification-Mediated Protein–Protein Interactions
- (2012) Xiang Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Chromatin as an expansive canvas for chemical biology
- (2012) Beat Fierz et al. Nature Chemical Biology
- Epigenetic protein families: a new frontier for drug discovery
- (2012) Cheryl H. Arrowsmith et al. NATURE REVIEWS DRUG DISCOVERY
- The super elongation complex (SEC) family in transcriptional control
- (2012) Zhuojuan Luo et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Perceiving the epigenetic landscape through histone readers
- (2012) Catherine A Musselman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Leukemia Fusion Target AF9 Is an Intrinsically Disordered Transcriptional Regulator that Recruits Multiple Partners via Coupled Folding and Binding
- (2012) Benjamin I. Leach et al. STRUCTURE
- Signals and Combinatorial Functions of Histone Modifications
- (2011) Tamaki Suganuma et al. Annual Review of Biochemistry
- Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin
- (2011) N. He et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- The Language of Histone Crosstalk
- (2010) Jung-Shin Lee et al. CELL
- Approach to Profile Proteins That Recognize Post-Translationally Modified Histone “Tails”
- (2010) Xiang Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
- (2010) Julia M. Wagner et al. Clinical Epigenetics
- Molecular replacement withMOLREP
- (2009) Alexei Vagin et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- YEATS domain proteins: a diverse family with many links to chromatin modification and transcriptionThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.
- (2009) Julia M. Schulze et al. Biochemistry and Cell Biology
- A feature-based approach to modeling protein–protein interaction hot spots
- (2009) Kyu-il Cho et al. NUCLEIC ACIDS RESEARCH
- Crosstalk among Histone Modifications
- (2008) Tamaki Suganuma et al. CELL
- Chemical probes for histone-modifying enzymes
- (2008) Philip A Cole Nature Chemical Biology
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started