Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Drug repositioning screening identifies etravirine as a potential therapeutic for friedreich's ataxia
Authors
Keywords
-
Journal
MOVEMENT DISORDERS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-01-09
DOI
10.1002/mds.27604
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Effect of diazoxide on Friedreich ataxia models
- (2018) Antonella Santoro et al. HUMAN MOLECULAR GENETICS
- Ribosome profiling uncovers selective mRNA translation associated with eIF2 phosphorylation in erythroid progenitors
- (2018) Nahuel A. Paolini et al. PLoS One
- Translational regulation is a key determinant of the cellular response to benzo[ a ]pyrene
- (2018) Evelyn Smit et al. TOXICOLOGY LETTERS
- Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat
- (2018) Liande Li et al. Nucleic Acid Therapeutics
- Pharmacological therapeutics in Friedreich ataxia: the present state
- (2017) Cassandra Strawser et al. Expert Review of Neurotherapeutics
- E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia
- (2017) Monica Benini et al. Cell Reports
- Pharmacological therapeutics in Friedreich ataxia: the present state
- (2017) Cassandra Strawser et al. Expert Review of Neurotherapeutics
- Giving Drugs a Second Chance: Overcoming Regulatory and Financial Hurdles in Repurposing Approved Drugs As Cancer Therapeutics
- (2017) J. Javier Hernandez et al. Frontiers in Oncology
- Ribosome Profiling Reveals Translational Upregulation of Cellular Oxidative Phosphorylation mRNAs during Vaccinia Virus-Induced Host Shutoff
- (2016) Aimei Dai et al. JOURNAL OF VIROLOGY
- Reversal of epigenetic promoter silencing in Friedreich ataxia by a class I histone deacetylase inhibitor
- (2016) Yogesh K. Chutake et al. NUCLEIC ACIDS RESEARCH
- Translating HDAC inhibitors in Friedreich’s ataxia
- (2016) Elisabetta Soragni et al. Expert Opinion on Orphan Drugs
- Long-term efficacy and safety of etravirine-containing regimens in a real-life cohort of treatment-experienced HIV-1-infected patients
- (2016) Clotilde Allavena et al. Infectious Diseases
- Computational and Experimental Advances in Drug Repositioning for Accelerated Therapeutic Stratification
- (2015) Khader Shameer et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Highly specific ubiquitin-competing molecules effectively promote frataxin accumulation and partially rescue the aconitase defect in Friedreich ataxia cells
- (2015) Alessandra Rufini et al. NEUROBIOLOGY OF DISEASE
- The Pathogenesis of Cardiomyopathy in Friedreich Ataxia
- (2015) Arnulf H. Koeppen et al. PLoS One
- Dyclonine rescues frataxin deficiency in animal models and buccal cells of patients with Friedreich's ataxia
- (2014) Sunil Sahdeo et al. HUMAN MOLECULAR GENETICS
- Epigenetic and neurological effects and safety of high-dose nicotinamide in patients with Friedreich's ataxia: an exploratory, open-label, dose-escalation study
- (2014) Vincenzo Libri et al. LANCET
- mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation
- (2013) Masahiro Morita et al. Cell Metabolism
- Mitochondrial pathophysiology in Friedreich's ataxia
- (2013) Pilar González-Cabo et al. JOURNAL OF NEUROCHEMISTRY
- Frataxin: a protein in search for a function
- (2013) Annalisa Pastore et al. JOURNAL OF NEUROCHEMISTRY
- Clinical features of Friedreich's ataxia: classical and atypical phenotypes
- (2013) Michael H. Parkinson et al. JOURNAL OF NEUROCHEMISTRY
- Friedreich Ataxia: Neuropathology Revised
- (2013) Arnulf H. Koeppen et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability
- (2013) Iris Usach et al. Journal of the International AIDS Society
- Translation Regulation as a Therapeutic Target in Cancer: Figure 1.
- (2012) Michal Grzmil et al. CANCER RESEARCH
- Interferon gamma upregulates frataxin and corrects the functional deficits in a Friedreich ataxia model
- (2012) B. Tomassini et al. HUMAN MOLECULAR GENETICS
- Friedreich's ataxia: Past, present and future
- (2011) Daniele Marmolino BRAIN RESEARCH REVIEWS
- Drug repositioning for orphan diseases
- (2011) D. Sardana et al. BRIEFINGS IN BIOINFORMATICS
- Preventing the ubiquitin–proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia
- (2011) Alessandra Rufini et al. HUMAN MOLECULAR GENETICS
- Efficacy and safety of etravirine at week 96 in treatment-experienced HIV type-1-infected patients in the DUET-1 and DUET-2 trials
- (2010) Christine Katlama et al. ANTIVIRAL THERAPY
- Human Iron−Sulfur Cluster Assembly, Cellular Iron Homeostasis, and Disease
- (2010) Hong Ye et al. BIOCHEMISTRY
- Molecular control of the cytosolic aconitase/IRP1 switch by extramitochondrial frataxin
- (2010) Ivano Condò et al. HUMAN MOLECULAR GENETICS
- The dorsal root ganglion in Friedreich’s ataxia
- (2009) Arnulf H. Koeppen et al. ACTA NEUROPATHOLOGICA
- Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: A review of the last 20 years (1989–2009)
- (2009) Marie-Pierre de Béthune ANTIVIRAL RESEARCH
- SUnSET, a nonradioactive method to monitor protein synthesis
- (2009) Enrico K Schmidt et al. NATURE METHODS
- Statistical methods for analysis of high-throughput RNA interference screens
- (2009) Amanda Birmingham et al. NATURE METHODS
- Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia
- (2009) Vincent Paupe et al. PLoS One
- Epigenetic Silencing in Friedreich Ataxia Is Associated with Depletion of CTCF (CCCTC-Binding Factor) and Antisense Transcription
- (2009) Irene De Biase et al. PLoS One
- The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP
- (2008) Ilaria Napoli et al. CELL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started