Peptide-Based Drug-Delivery Systems in Biotechnological Applications: Recent Advances and Perspectives

Amyloid-Like Fibrillary Morphology Originated by Tyrosine-Containing Aromatic Hexapeptides

(2018) Carlo Diaferia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structural Characterization of Self-Assembled Tetra-Tryptophan Based Nanostructures: Variations on a Common Theme

(2018) Carlo Diaferia et al.   CHEMPHYSCHEM

Cell Penetrating Peptides as Molecular Carriers for Anti-Cancer Agents

(2018) Antonella Borrelli et al.   MOLECULES

Improving the Mechanical Rigidity of Hyaluronic Acid by Integration of Supramolecular Peptide Matrix

(2018) Moran Aviv et al.   ACS Applied Materials & Interfaces

Design of an Amphiphilic iRGD Peptide and Self-Assembling Nanovesicles for Improving Tumor Accumulation and Penetration and the Photodynamic Efficacy of the Photosensitizer

(2018) Yue Jiang et al.   ACS Applied Materials & Interfaces

iRGD-decorated reduction-responsive nanoclusters for targeted drug delivery

(2018) Hang Hu et al.   Nanoscale

1988–2018: Thirty years of drug smuggling at the nano scale. Challenges and opportunities of cell-penetrating peptides in biomedical research

(2018) Maria Gallo et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Peptide-decorated polymeric nanomedicines for precision cancer therapy

(2018) Huanli Sun et al.   JOURNAL OF CONTROLLED RELEASE

UV Light-Responsive Peptide-Based Supramolecular Hydrogel for Controlled Drug Delivery

(2018) Michal E. Roth-Konforti et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Liposomes derivatized with multimeric copies of KCCYSL peptide as targeting agents for HER-2-overexpressing tumor cells

(2017) Paola Ringhieri et al.   International Journal of Nanomedicine

iRGD-modified lipid–polymer hybrid nanoparticles loaded with isoliquiritigenin to enhance anti-breast cancer effect and tumor-targeting ability

(2017) Fei Gao et al.   International Journal of Nanomedicine

Covalent diphenylalanine peptide nanotube conjugated to folic acid/magnetic nanoparticles for anti-cancer drug delivery

(2017) Giti Emtiazi et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment

(2017) Renata Jaskula-Sztul et al.   Journal of Materials Chemistry B

Antitumor Photodynamic Therapy Based on Dipeptide Fibrous Hydrogels with Incorporation of Photosensitive Drugs

(2017) Manzar Abbas et al.   ACS Biomaterials-Science & Engineering

Antitumor Photodynamic Therapy Based on Dipeptide Fibrous Hydrogels with Incorporation of Photosensitive Drugs

(2017) Manzar Abbas et al.   ACS Biomaterials Science & Engineering

Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin

(2017) Carlo Diaferia et al.   Scientific Reports

Linear and nonlinear optical waveguiding in bio-inspired peptide nanotubes

(2016) Amir Handelman et al.   Acta Biomaterialia

Fabrication of Plasmonic Nanorod-Embedded Dipeptide Microspheres via the Freeze-Quenching Method for Near-Infrared Laser-Triggered Drug-Delivery Applications

(2016) Hakan Erdogan et al.   BIOMACROMOLECULES

Thailandepsin A-loaded and octreotide-functionalized unimolecular micelles for targeted neuroendocrine cancer therapy

(2016) Renata Jaskula-Sztul et al.   BIOMATERIALS

KE108-conjugated unimolecular micelles loaded with a novel HDAC inhibitor thailandepsin-A for targeted neuroendocrine cancer therapy

(2016) Guojun Chen et al.   BIOMATERIALS

One-Pot Synthesis of Diphenylalanine-Based Hybrid Nanospheres for Controllable pH- and GSH-Responsive Delivery of Drugs

(2016) Qiuju Li et al.   CHEMISTRY OF MATERIALS

Hierarchical Analysis of Self-Assembled PEGylated Hexaphenylalanine Photoluminescent Nanostructures

(2016) Carlo Diaferia et al.   CHEMISTRY-A EUROPEAN JOURNAL

Effect of ligand density and PEG modification on octreotide-targeted liposome via somatostatin receptor in vitro and in vivo

(2016) Huipeng Li et al.   DRUG DELIVERY

Reducible self-assembling cationic polypeptide-based micelles mediate co-delivery of doxorubicin and microRNA-34a for androgen-independent prostate cancer therapy

(2016) Chong Yao et al.   JOURNAL OF CONTROLLED RELEASE

Gadolinium containing telechelic PEG-polymers end-capped by di-phenylalanine motives as potential supramolecular MRI contrast agents

(2016) Carlo Diaferia et al.   JOURNAL OF PEPTIDE SCIENCE

Piezoelectric properties of diphenylalanine microtubes prepared from the solution

(2016) Semen Vasilev et al.   JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS

iRGD decorated lipid-polymer hybrid nanoparticles for targeted co-delivery of doxorubicin and sorafenib to enhance anti-hepatocellular carcinoma efficacy

(2016) Jinming Zhang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Calcium-Ion-Triggered Co-assembly of Peptide and Polysaccharide into a Hybrid Hydrogel for Drug Delivery

(2016) Yanyan Xie et al.   Nanoscale Research Letters

Direct subphthalocyanine conjugation to bombesin vs. indirect conjugation to its lipidic nanocarrier

(2016) Yann Bernhard et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Low-temperature photoluminescence in self-assembled diphenylalanine microtubes

(2016) T. Nikitin et al.   PHYSICS LETTERS A

Polycaprolactone fibers with self-assembled peptide micro/nanotubes: a practical route towards enhanced mechanical strength and drug delivery applications

(2016) M. S. Liberato et al.   Journal of Materials Chemistry B

Calcium-Ion-Triggered Co-assembly of Peptide and Polysaccharide into a Hybrid Hydrogel for Drug Delivery

(2016) Yanyan Xie et al.   Nanoscale Research Letters

Peptide Materials Obtained by Aggregation of Polyphenylalanine Conjugates as Gadolinium-Based Magnetic Resonance Imaging Contrast Agents

(2015) Carlo Diaferia et al.   ADVANCED FUNCTIONAL MATERIALS

Review peptide-targeted liposomes for selective drug delivery: Advantages and problematic issues

(2015) Antonella Accardo et al.   BIOPOLYMERS

Sticky tubes and magnetic hydrogels co-assembled by a short peptide and melanin-like nanoparticles

(2015) Priyadip Das et al.   CHEMICAL COMMUNICATIONS

Conformational Ensembles Explored Dynamically from Disordered Peptides Targeting Chemokine Receptor CXCR4

(2015) Marian Vincenzi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery

(2015) Paola Ringhieri et al.   JOURNAL OF PEPTIDE SCIENCE

Reconstructive Phase Transition in Ultrashort Peptide Nanostructures and Induced Visible Photoluminescence

(2015) Amir Handelman et al.   LANGMUIR

Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles

(2015) Marian Vincenzi et al.   Molecular BioSystems

The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine

(2015) Silvia Marchesan et al.   MOLECULES

CPPsite 2.0: a repository of experimentally validated cell-penetrating peptides

(2015) Piyush Agrawal et al.   NUCLEIC ACIDS RESEARCH

Dipeptide Nanotubes Containing Unnatural Fluorine-Substituted β2,3-Diarylamino Acid and l-Alanine as Candidates for Biomedical Applications

(2015) Andrea Bonetti et al.   ORGANIC LETTERS

Self-Assembling Peptide of d-Amino Acids Boosts Selectivity and Antitumor Efficacy of 10-Hydroxycamptothecin

(2014) Jianfeng Liu et al.   ACS Applied Materials & Interfaces

Enzyme-Responsive Release of Doxorubicin from Monodisperse Dipeptide-Based Nanocarriers for Highly Efficient Cancer Treatment In Vitro

(2014) He Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

The Powerful Functions of Peptide-Based Bioactive Matrices for Regenerative Medicine

(2014) Charles M. Rubert Pérez et al.   ANNALS OF BIOMEDICAL ENGINEERING

Influence of PEG length on conformational and binding properties of CCK peptides exposed by supramolecular aggregates

(2014) Antonella Accardo et al.   BIOPOLYMERS

Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes

(2014) Paola Ringhieri et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

RGD-fatty alcohol-modified docetaxel liposomes improve tumor selectivity in vivo

(2014) Yinghuan Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

RGD peptide conjugated liposomal drug delivery system for enhance therapeutic efficacy in treating bone metastasis from prostate cancer

(2014) Fangfang Wang et al.   JOURNAL OF CONTROLLED RELEASE

Preparation and characterization of photo-responsive cell-penetrating peptide-mediated nanostructured lipid carrier

(2014) Yang Yang et al.   JOURNAL OF DRUG TARGETING

Structural and optical properties of short peptides: nanotubes-to-nanofibers phase transformation

(2014) Amir Handelman et al.   JOURNAL OF PEPTIDE SCIENCE

Enhancement of the Uptake and Cytotoxic Activity of Doxorubicin in Cancer Cells by Novel cRGD-Semipeptide-Anchoring Liposomes

(2014) Lucia Battistini et al.   MOLECULAR PHARMACEUTICS

PEG spacers of different length influence the biological profile of bombesin-based radiolabeled antagonists

(2014) Mazen Jamous et al.   NUCLEAR MEDICINE AND BIOLOGY

Short peptide based self-assembled nanostructures: implications in drug delivery and tissue engineering

(2014) Jiban Jyoti Panda et al.   Polymer Chemistry

Legumain protease-activated TAT-liposome cargo for targeting tumours and their microenvironment

(2014) Ze Liu et al.   Nature Communications

Cyclic RGD-Linked Polymeric Micelles for Targeted Delivery of Platinum Anticancer Drugs to Glioblastoma through the Blood–Brain Tumor Barrier

(2013) Yutaka Miura et al.   ACS Nano

A pH-responsive α-helical cell penetrating peptide-mediated liposomal delivery system

(2013) Qianyu Zhang et al.   BIOMATERIALS

A Label-Free, Quantitative Assay of Amyloid Fibril Growth Based on Intrinsic Fluorescence

(2013) Dorothea Pinotsi et al.   CHEMBIOCHEM

Improvement of pharmacokinetic and antitumor activity of PEGylated liposomal doxorubicin by targeting with N-methylated cyclic RGD peptide in mice bearing C-26 colon carcinomas

(2013) Mohamadreza Amin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Doxorubicin-Loaded Cyclic Peptide Nanotube Bundles Overcome Chemoresistance in Breast Cancer Cells

(2013) Yongzhong Wang et al.   Journal of Biomedical Nanotechnology

Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery

(2013) Antonella Accardo et al.   JOURNAL OF PEPTIDE SCIENCE

Dephosphorylation of d-Peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/Hydrogels and Their Potential Applications for Intracellular Imaging and Intratumoral Chemotherapy

(2013) Jiayang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interaction between a Cationic Surfactant-like Peptide and Lipid Vesicles and Its Relationship to Antimicrobial Activity

(2013) Ashkan Dehsorkhi et al.   LANGMUIR

l-Diphenylalanine Microtubes As a Potential Drug-Delivery System: Characterization, Release Kinetics, and Cytotoxicity

(2013) Rondes F. Silva et al.   LANGMUIR

Solution conformational features and interfacial properties of an intrinsically disordered peptide coupled to alkyl chains: a new class of peptide amphiphiles

(2013) Antonella Accardo et al.   Molecular BioSystems

Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions

(2013) Antonella Accardo et al.   NEW JOURNAL OF CHEMISTRY

Cholesterol-Peptide Hybrids to Form Liposome-Like Vesicles for Gene Delivery

(2013) Qiong Tang et al.   PLoS One

Quantitative Evaluation of Bioorthogonal Chemistries for Surface Functionalization of Nanoparticles

(2012) Lise N. Feldborg et al.   BIOCONJUGATE CHEMISTRY

Arginine-rich self-assembling peptides as potent antibacterial gels

(2012) Ana Salomé Veiga et al.   BIOMATERIALS

Design and properties of functional nanotubes from the self-assembly of cyclic peptide templates

(2012) Robert Chapman et al.   CHEMICAL SOCIETY REVIEWS

Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: a potential theranostic agent

(2012) Giancarlo Morelli et al.   International Journal of Nanomedicine

Cyclic RGD peptide-modified liposomal drug delivery system: enhanced cellular uptake in vitro and improved pharmacokinetics in rats

(2012) Zhongya Chen et al.   International Journal of Nanomedicine

Molecular binding of self-assembling peptide EAK16-II with anticancer agent EPT and its implication in cancer cell inhibition

(2012) Sheng Lu et al.   JOURNAL OF CONTROLLED RELEASE

Positron emission tomography evaluation of somatostatin receptor targeted 64Cu-TATE-liposomes in a human neuroendocrine carcinoma mouse model

(2012) Anncatrine L. Petersen et al.   JOURNAL OF CONTROLLED RELEASE

Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells

(2012) Antonella Accardo et al.   JOURNAL OF DRUG TARGETING

In Vivo Studies of Octreotide-Modified N-Octyl-O, N-Carboxymethyl Chitosan Micelles Loaded with Doxorubicin for Tumor-Targeted Delivery

(2012) Aifeng Zou et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

d-Amino Acids Boost the Selectivity and Confer Supramolecular Hydrogels of a Nonsteroidal Anti-Inflammatory Drug (NSAID)

(2012) Jiayang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RGD-Based Strategies To Target Alpha(v) Beta(3) Integrin in Cancer Therapy and Diagnosis

(2012) Fabienne Danhier et al.   MOLECULAR PHARMACEUTICS

Nanostructure-templated control of drug release from peptide amphiphile nanofiber gels

(2012) John B. Matson et al.   Soft Matter

Charged Diphenylalanine Nanotubes and Controlled Hierarchical Self-Assembly

(2011) Minjie Wang et al.   ACS Nano

The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles

(2011) Yang Zhang et al.   BIOMATERIALS

Conjugation of two complementary anti-cancer drugs confers molecular hydrogels as a co-delivery system

(2011) Lina Mao et al.   CHEMICAL COMMUNICATIONS

Targeting properties of peptide-modified radiolabeled liposomal nanoparticles

(2011) Anna Helbok et al.   Nanomedicine-Nanotechnology Biology and Medicine

Self-assembly of amphiphilic peptides

(2011) I. W. Hamley   Soft Matter

Self-Assembled Organic Nanostructures with Metallic-Like Stiffness

(2010) Lihi Adler-Abramovich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phage display: Concept, innovations, applications and future

(2010) Jyoti Pande et al.   BIOTECHNOLOGY ADVANCES

Power struggles in peptide-amphiphile nanostructures

(2010) Frank Versluis et al.   CHEMICAL SOCIETY REVIEWS

Self-assembly and application of diphenylalanine-based nanostructures

(2010) Xuehai Yan et al.   CHEMICAL SOCIETY REVIEWS

Nanofiber formation of amphiphilic cyclic tri-β-peptide

(2010) Yusuke Ishihara et al.   JOURNAL OF PEPTIDE SCIENCE

Peptide modified nanocarriers for selective targeting of bombesin receptors

(2010) Antonella Accardo et al.   Molecular BioSystems

Amphiphilic CCK peptides assembled in supramolecular aggregates: structural investigations and in vitro studies

(2010) Antonella Accardo et al.   Molecular BioSystems

Internalization of p5314−29Peptide Amphiphiles and Subsequent Endosomal Disruption Results in SJSA-1 Cell Death

(2010) Dimitris Missirlis et al.   MOLECULAR PHARMACEUTICS

Enhanced antitumor effect of novel dual-targeted paclitaxel liposomes

(2010) Shuyan Meng et al.   NANOTECHNOLOGY

Targeted Polymeric Micelle System for Delivery of Combretastatin A4 to Tumor Vasculature In Vitro

(2010) Yiguang Wang et al.   PHARMACEUTICAL RESEARCH

Potential mechanisms of prospective antimigraine drugs: A focus on vascular (side) effects

(2010) Kayi Y. Chan et al.   PHARMACOLOGY & THERAPEUTICS

Self-Assembly of Phenylalanine Oligopeptides: Insights from Experiments and Simulations

(2009) Phanourios Tamamis et al.   BIOPHYSICAL JOURNAL

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

(2009) Kazuki N. Sugahara et al.   CANCER CELL

Supramolecular aggregates containing lipophilic Gd(III) complexes as contrast agents in MRI

(2009) Antonella Accardo et al.   COORDINATION CHEMISTRY REVIEWS

RGD-modified polymeric micelles as potential carriers for targeted delivery to integrin-overexpressing tumor vasculature and tumor cells

(2009) Yiguang Wang et al.   JOURNAL OF DRUG TARGETING

Supramolecular Hydrogel of ad-Amino Acid Dipeptide for Controlled Drug Release in Vivo†

(2009) Gaolin Liang et al.   LANGMUIR

Self-Assembly of Giant Peptide Nanobelts

(2009) Honggang Cui et al.   NANO LETTERS

Self-assembled arrays of peptide nanotubes by vapour deposition

(2009) Lihi Adler-Abramovich et al.   Nature Nanotechnology

Peptide-Containing Aggregates as Selective Nanocarriers for Therapeutics

(2008) Antonella Accardo et al.   ChemMedChem

Targeting colon cancer cells using PEGylated liposomes modified with a fibronectin-mimetic peptide

(2008) Ashish Garg et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

RGD-based strategies for improving antitumor activity of paclitaxel-loaded liposomes in nude mice xenografted with human ovarian cancer

(2008) Hui Zhao et al.   JOURNAL OF DRUG TARGETING

A Periodic Table of Coiled-Coil Protein Structures

(2008) Efrosini Moutevelis et al.   JOURNAL OF MOLECULAR BIOLOGY

Micelles derivatized with octreotide as potential target-selective contrast agents in MRI

(2008) Anna Morisco et al.   JOURNAL OF PEPTIDE SCIENCE

Self-assembling peptide nanotubes

(2008) Shane Scanlon et al.   Nano Today

Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis

(2008) E. A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA