Structure Identification of ViceninII Extracted from Dendrobium officinale and the Reversal of TGF-β1-Induced Epithelial–Mesenchymal Transition in Lung Adenocarcinoma Cells through TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways

Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer

(2018) Chang Li et al.   CANCER LETTERS

Simultaneous identification and determination of flavonoids in Dendrobium officinale

(2018) Chunhua Zhou et al.   Chemistry Central Journal

Isoviolanthin Extracted from Dendrobium officinale Reverses TGF-β1-Mediated Epithelial–Mesenchymal Transition in Hepatocellular Carcinoma Cells via Deactivating the TGF-β/Smad and PI3K/Akt/mTOR Signaling Pathways

(2018) Shangping Xing et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Epithelial-mesenchymal transition leads to NK cell–mediated metastasis-specific immunosurveillance in lung cancer

(2018) Peter J. Chockley et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatoprotective Effect of Polysaccharides Isolated from Dendrobium officinale against Acetaminophen-Induced Liver Injury in Mice via Regulation of the Nrf2-Keap1 Signaling Pathway

(2018) Guosheng Lin et al.   Oxidative Medicine and Cellular Longevity

Vicenin-2 inhibits Wnt/β-catenin signaling and induces apoptosis in HT-29 human colon cancer cell line

(2018) Dong Yang et al.   Drug Design Development and Therapy

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Physicochemical properties of polysaccharides from Dendrobium officinale by fractional precipitation and their preliminary antioxidant and anti-HepG2 cells activities in vitro

(2018) Shangping Xing et al.   Chemistry Central Journal

Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling

(2018) Honglei Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Structural Characterization of Polysaccharides from Dendrobium officinale and Their Effects on Apoptosis of HeLa Cell Line

(2018) Wenxia Yu et al.   MOLECULES

PI3K/Akt/HIF-1α signaling pathway mediates HPV-16 oncoprotein-induced expression of EMT-related transcription factors in non-small cell lung cancer cells

(2018) Jinhua Liu et al.   Journal of Cancer

Vicenin-2 acts as a radiosensitizer of the non-small cell lung cancer by lowering Akt expression

(2018) Taranga Jyoti Baruah et al.   BIOFACTORS

Isolation of polysaccharides from Dendrobium officinale leaves and anti-inflammatory activity in LPS-stimulated THP-1 cells

(2018) Min Zhang et al.   Chemistry Central Journal

SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis

(2018) Xu Zhang et al.   Cancer Management and Research

Cinnamomum cassia extracts reverses TGF-β1-induced epithelial-mesenchymal transition in human lung adenocarcinoma cells and suppresses tumor growth in vivo

(2017) Chin-Yin Lin et al.   ENVIRONMENTAL TOXICOLOGY

Upholding a role for EMT in pancreatic cancer metastasis

(2017) Nicole M. Aiello et al.   NATURE

Osthole inhibited TGF β-induced epithelial–mesenchymal transition (EMT) by suppressing NF-κB mediated Snail activation in lung cancer A549 cells

(2017) Haitao Feng et al.   Cell Adhesion & Migration

Vicenin-2 and scolymoside inhibit high-glucose-induced vascular inflammation in vitro and in vivo

(2016) Sae-Kwang Ku et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Ginkgolic Acid Inhibits Invasion and Migration and TGF-β-Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

(2016) Seung Ho Baek et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Purification, Characterization and Biological Activity of Polysaccharides from Dendrobium officinale

(2016) Kaiwei Huang et al.   MOLECULES

The biological role of epithelial-mesenchymal transition in lung cancer (Review)

(2016) Woo Jung Sung et al.   ONCOLOGY REPORTS

Nobiletin inhibits epithelial-mesenchymal transition of human non-small cell lung cancer cells by antagonizing the TGF-β1/Smad3 signaling pathway

(2016) CHUNLI DA et al.   ONCOLOGY REPORTS

Ultrafiltration coupled with high-performance liquid chromatography and quadrupole-time-of-flight mass spectrometry for screening lipase binders from different extracts of Dendrobium officinale

(2015) Yi Tao et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Antithrombotic and antiplatelet activities of vicenin-2

(2015) Wonhwa Lee et al.   BLOOD COAGULATION & FIBRINOLYSIS

Patients of all ages with advanced non-small cell lung cancer are not receiving chemotherapy

(2015) Mary Kay Barton   CA-A CANCER JOURNAL FOR CLINICIANS

Antiseptic effect of vicenin-2 and scolymoside from Cyclopia subternata (honeybush) in response to HMGB1 as a late sepsis mediator in vitro and in vivo

(2015) Wonhwa Lee et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Study on Dendrobium officinale O-acetyl-glucomannan (Dendronan®): Part VI. Protective effects against oxidative stress in immunosuppressed mice

(2015) Xiaojun Huang et al.   FOOD RESEARCH INTERNATIONAL

Ameliorative Effect of Vicenin-2 and Scolymoside on TGFBIp-Induced Septic Responses

(2015) Wonhwa Lee et al.   INFLAMMATION

Anti-inflammatory effects of vicenin-2 and scolymoside in vitro and in vivo

(2015) Hyejin Kang et al.   INFLAMMATION RESEARCH

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Kaempferol Suppresses Transforming Growth Factor-β1–Induced Epithelial-to-Mesenchymal Transition and Migration of A549 Lung Cancer Cells by Inhibiting Akt1-Mediated Phosphorylation of Smad3 at Threonine-179

(2015) Eunji Jo et al.   NEOPLASIA

Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties

(2014) Md. Nurul Islam et al.   FOOD AND CHEMICAL TOXICOLOGY

Mass Spectrometry of Flavonoid Vicenin-2, Based Sunlight Barriers in Lychnophora species

(2014) Denise Brentan Silva et al.   Scientific Reports

Epithelial-mesenchymal plasticity in carcinoma metastasis

(2013) J. H. Tsai et al.   GENES & DEVELOPMENT

Evaluation of Intestinal Permeability of Vicenin-2 and Lychnopholic Acid from Lychnophora salicifolia (Brazilian Arnicão) Using Caco-2 Cells

(2013) Dayana Rubio Gouvea et al.   JOURNAL OF NATURAL PRODUCTS

Testing of Perilla frutescens extract and Vicenin 2 for their antispasmodic effect

(2013) Eugen J. Verspohl et al.   PHYTOMEDICINE

Local recurrence following lung cancer surgery: Incidence, risk factors, and outcomes

(2013) David Fedor et al.   SURGICAL ONCOLOGY-OXFORD

Review of research on Dendrobium, a prized folk medicine

(2012) Tzi Bun Ng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Molecular Pathways: Targeting the TGF-  Pathway for Cancer Therapy

(2012) A. L. Smith et al.   CLINICAL CANCER RESEARCH

Anti-cancer effects of novel flavonoid vicenin-2 as a single agent and in synergistic combination with docetaxel in prostate cancer

(2011) Lokesh Dalasanur Nagaprashantha et al.   BIOCHEMICAL PHARMACOLOGY

Vicenin-2, a Potential Anti-inflammatory Constituent ofUrtica circularis

(2011) Carla Marrassini et al.   JOURNAL OF NATURAL PRODUCTS

FGF-1 reverts epithelial-mesenchymal transition induced by TGF-β1 through MAPK/ERK kinase pathway

(2010) Carlos Ramos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations

(2008) J LOPICCOLO et al.   DRUG RESISTANCE UPDATES

C-glycosyl flavones from Peperomia blanda

(2008) Leosvaldo S.M. Velozo et al.   FITOTERAPIA