Inverse Molecular Docking as a Novel Approach to Study Anticarcinogenic and Anti-Neuroinflammatory Effects of Curcumin

Structural, Functional, and Clinical Characterization of a NovelPTPN11Mutation Cluster Underlying Noonan Syndrome

(2017) Luca Pannone et al.   HUMAN MUTATION

Core-shell nanofibers of curcumin/cyclodextrin inclusion complex and polylactic acid: Enhanced water solubility and slow release of curcumin

(2017) Zeynep Aytac et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Curcumin and Salsalate Suppresses Colonic Inflammation and Procarcinogenic Signaling in High-Fat-Fed, Azoxymethane-Treated Mice

(2017) Xian Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Improved Chemical Stability and Antiproliferative Activities of Curcumin-Loaded Nanoparticles with a Chitosan Chlorogenic Acid Conjugate

(2017) Yuting Fan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Biocompatible Lipid Nanoparticles as Carriers To Improve Curcumin Efficacy in Ovarian Cancer Treatment

(2017) Maria Luisa Bondì et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Curcumin Induces Apoptosis of Colorectal Cancer Stem Cells by Coupling with CD44 Marker

(2016) Yu-Ting Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Screening Explorer–An Interactive Tool for the Analysis of Screening Results

(2016) Charly Empereur-Mot et al.   Journal of Chemical Information and Modeling

Discovery of Mycobacterium tuberculosis InhA Inhibitors by Binding Sites Comparison and Ligands Prediction

(2016) Tanja Štular et al.   JOURNAL OF MEDICINAL CHEMISTRY

The role of natural polyphenols in cell signaling and cytoprotection against cancer development

(2016) Hanna Lewandowska et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The ChEMBL database in 2017

(2016) Anna Gaulton et al.   NUCLEIC ACIDS RESEARCH

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

(2016) Bertrand Simon et al.   STRUCTURE

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

(2016) Gang Wang et al.   Oncotarget

ProBiS-CHARMMing: Web Interface for Prediction and Optimization of Ligands in Protein Binding Sites

(2015) Janez Konc et al.   Journal of Chemical Information and Modeling

Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? The Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors

(2015) Mehrdad Iranshahi et al.   JOURNAL OF NATURAL PRODUCTS

PLIP: fully automated protein–ligand interaction profiler

(2015) Sebastian Salentin et al.   NUCLEIC ACIDS RESEARCH

Dendrosomal curcumin increases expression of the long non-coding RNA gene MEG3 via up-regulation of epi-miRs in hepatocellular cancer

(2015) Mina Zamani et al.   PHYTOMEDICINE

Tumour growth inhibition and anti-angiogenic effects using curcumin correspond to combined PDE2 and PDE4 inhibition

(2015) Abdurazzag Abusnina et al.   THROMBOSIS AND HAEMOSTASIS

Predictiveness curves in virtual screening

(2015) Charly Empereur-mot et al.   Journal of Cheminformatics

The folate receptor as a rational therapeutic target for personalized cancer treatment

(2014) Yehuda G. Assaraf et al.   DRUG RESISTANCE UPDATES

Small Molecule Inhibitors Targeting Activator Protein 1 (AP-1)

(2014) Na Ye et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combined administration of curcumin and gallic acid inhibits gallic acid-induced suppression of steroidogenesis, sperm output, antioxidant defenses and inflammatory responsive genes

(2014) Sunny O. Abarikwu et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders

(2014) Song-Yu Yang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Augmented sensitivity to methotrexate by curcumin induced overexpression of folate receptor in KG-1 cells

(2013) Sugapriya Dhanasekaran et al.   BIOCHIMIE

Curcumin and its Derivatives: Their Application in Neuropharmacology and Neuroscience in the 21st Century

(2013) Wing-Hin Lee et al.   Current Neuropharmacology

Preparation of Chitosan-Coated Nanoliposomes for Improving the Mucoadhesive Property of Curcumin Using the Ethanol Injection Method

(2013) Gye Hwa Shin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Identification of Novel Phosphodiesterase-4D Inhibitors Prescreened by Molecular Dynamics-Augmented Modeling and Validated by Bioassay

(2013) Zhe Li et al.   Journal of Chemical Information and Modeling

Molecular dynamics simulations give insight into d-glucose dioxidation at C2 and C3 by Agaricus meleagris pyranose dehydrogenase

(2013) Michael M. H. Graf et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Crystal structure analysis of human Sirt2 and its ADP-ribose complex

(2013) Sébastien Moniot et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition

(2013) A. S. Wibowo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin Inhibits Tumor Growth and Angiogenesis in an Orthotopic Mouse Model of Human Pancreatic Cancer

(2013) Sabrina Bimonte et al.   Biomed Research International

A novelHRASsubstitution (c.266C>G; p.S89C) resulting in decreased downstream signaling suggests a new dimension of RAS pathway dysregulation in human development

(2012) Karen W. Gripp et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Curcumin-induced autophagy contributes to the decreased survival of oral cancer cells

(2012) Ji Young Kim et al.   ARCHIVES OF ORAL BIOLOGY

Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

(2012) Nitzan Gonen et al.   DRUG RESISTANCE UPDATES

Antioxidant Activities of Curcumin and Ascorbyl Dipalmitate Nanoparticles and Their Activities after Incorporation into Cellulose-Based Packaging Films

(2012) Piyapong Sonkaew et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dehydrozingerone, a Structural Analogue of Curcumin, Induces Cell-Cycle Arrest at the G2/M Phase and Accumulates Intracellular ROS in HT-29 Human Colon Cancer Cells

(2012) Shingo Yogosawa et al.   JOURNAL OF NATURAL PRODUCTS

ProBiS-2012: web server and web services for detection of structurally similar binding sites in proteins

(2012) J. Konc et al.   NUCLEIC ACIDS RESEARCH

Crystal Structure of the Human Ecto-5′-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling

(2012) Karen Knapp et al.   STRUCTURE

Macrophage folate receptor-β (FR-β) expression in auto-immune inflammatory rheumatic diseases: A forthcoming marker for cardiovascular risk?

(2011) Nynke A. Jager et al.   AUTOIMMUNITY REVIEWS

Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo

(2011) Seung Joon Lee et al.   BMC CANCER

Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma

(2011) Reason Wilken et al.   Molecular Cancer

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1)

(2011) Xiangyu Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts

(2010) Marie-Claude Perry et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin Prevents Dopaminergic Neuronal Death Through Inhibition of the c-Jun N-Terminal Kinase Pathway

(2010) Song Yu et al.   REJUVENATION RESEARCH

Encapsulation of polyphenols – a review

(2010) Zhongxiang Fang et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

The effect of curcumin (turmeric) onAlzheimer′s disease: An overview

(2009) Shrikant Mishra et al.   Annals of Indian Academy of Neurology

Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells

(2009) Young-Ok Son et al.   APOPTOSIS

Structure and Inhibition of Human Diamine Oxidase

(2009) Aaron P. McGrath et al.   BIOCHEMISTRY

Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)

(2009) Song-Shei Lin et al.   CANCER LETTERS

Folate Receptor   Is Expressed by Tumor-Associated Macrophages and Constitutes a Marker for M2 Anti-inflammatory/Regulatory Macrophages

(2009) A. Puig-Kroger et al.   CANCER RESEARCH

Invasion of Human Breast Cancer Cells In vivo Requires Both Paracrine and Autocrine Loops Involving the Colony-Stimulating Factor-1 Receptor

(2009) A. Patsialou et al.   CANCER RESEARCH

Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety

(2009) Alex B Burgin et al.   NATURE BIOTECHNOLOGY

Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells

(2008) A. Kunwar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins

(2008) Ajaikumar B. Kunnumakkara et al.   CANCER LETTERS

Protection Against Aflatoxin B1-Induced Cytotoxicity by Expression of the Cloned Aflatoxin B1-Aldehyde Reductases Rat AKR7A1 and Human AKR7A3

(2008) Sridevi Bodreddigari et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Bioavailability of nanoparticles in nutrient and nutraceutical delivery

(2008) Edgar Acosta   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

The Crystal Structure of JNK2 Reveals Conformational Flexibility in the MAP Kinase Insert and Indicates Its Involvement in the Regulation of Catalytic Activity

(2008) David Shaw et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Basis for Substrate Promiscuity of dCK

(2008) Elisabetta Sabini et al.   JOURNAL OF MOLECULAR BIOLOGY