New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion

Advances and challenges in the search for D 2 and D 3 dopamine receptor-selective compounds

(2018) Amy E. Moritz et al.   CELLULAR SIGNALLING

Structure-activity relationship of a novel series of inhibitors for cancer type transporter L-type amino acid transporter 1 (LAT1)

(2017) Pornparn Kongpracha et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Intrinsic and Antipsychotic Drug-Induced Metabolic Dysfunction in Schizophrenia

(2017) Zachary Freyberg et al.   Frontiers in Neuroscience

Dopaminergic drugs in type 2 diabetes and glucose homeostasis

(2016) Felicitas Lopez Vicchi et al.   PHARMACOLOGICAL RESEARCH

Current drug treatments targeting dopamine D3 receptor

(2016) Gian Marco Leggio et al.   PHARMACOLOGY & THERAPEUTICS

Development of a Rapid Insulin Assay by Homogenous Time-Resolved Fluorescence

(2016) Zachary J. Farino et al.   PLoS One

Islet-specific monoamine oxidase A and B expression depends on MafA transcriptional activity and is compromised in type 2 diabetes

(2015) Elvira Ganic et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antihypertensive mechanisms of intra-renal dopamine

(2015) Ming-Zhi Zhang et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

System-L amino acid transporters play a key role in pancreatic β-cell signalling and function

(2015) Qi Cheng et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Olanzapine Is Faster than Haloperidol in Inducing Metabolic Abnormalities in Schizophrenic and Bipolar Patients

(2015) Michele Fabrazzo et al.   NEUROPSYCHOBIOLOGY

The renal dopaminergic system: novel diagnostic and therapeutic approaches in hypertension and kidney disease

(2015) Ines Armando et al.   Translational Research

Dopamine receptors - IUPHAR Review 13

(2014) Jean-Martin Beaulieu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Non-neural tyrosine hydroxylase, via modulation of endocrine pancreatic precursors, is required for normal development of beta cells in the mouse pancreas

(2014) Patricia Vázquez et al.   DIABETOLOGIA

Discovery, Optimization, and Characterization of Novel D2 Dopamine Receptor Selective Antagonists

(2014) Jingbo Xiao et al.   JOURNAL OF MEDICINAL CHEMISTRY

The role of D2-autoreceptors in regulating dopamine neuron activity and transmission

(2014) C.P. Ford   NEUROSCIENCE

Role of Metformin in Suppressing 1,2-Dimethylhydrazine-Induced Colon Cancer in Diabetic and Non-Diabetic Mice: Effect on Tumor Angiogenesis and Cell Proliferation

(2014) Dalia K. Zaafar et al.   PLoS One

Antipsychotic-Induced Insulin Resistance and Postprandial Hormonal Dysregulation Independent of Weight Gain or Psychiatric Disease

(2013) Karen L. Teff et al.   DIABETES

Estimating Dopamine D2 Receptor Occupancy for Doses of 8 Antipsychotics

(2013) Irene M. Lako et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Acute Effects of Single-Dose Olanzapine on Metabolic, Endocrine, and Inflammatory Markers in Healthy Controls

(2013) Margaret Karolina Hahn et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Minireview: Dopaminergic Regulation of Insulin Secretion from the Pancreatic Islet

(2013) Alessandro Ustione et al.   MOLECULAR ENDOCRINOLOGY

Molecular Determinants of Selectivity and Efficacy at the Dopamine D3 Receptor

(2012) Amy Hauck Newman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With ^|^alpha;-Alkyl Moieties

(2012) Narakorn Khunweeraphong et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Dopamine Synthesis and D3 Receptor Activation in Pancreatic β-Cells Regulates Insulin Secretion and Intracellular [Ca2+] Oscillations

(2012) Alessandro Ustione et al.   MOLECULAR ENDOCRINOLOGY

Dopamine-Mediated Autocrine Inhibitory Circuit Regulating Human Insulin Secretionin Vitro

(2012) Norman Simpson et al.   MOLECULAR ENDOCRINOLOGY

Apo-Ghrelin Receptor Forms Heteromers with DRD2 in Hypothalamic Neurons and Is Essential for Anorexigenic Effects of DRD2 Agonism

(2012) Andras Kern et al.   NEURON

Insulin Secretion and Sensitivity after Single-Dose Amisulpride, Olanzapine or Placebo in Young Male Subjects: Double Blind, Cross-Over Glucose Clamp Study

(2012) D. Kopf et al.   PHARMACOPSYCHIATRY

Dopamine and Vascular Dynamics Control: Present Status and Future Perspectives

(2011) Seyed Khosrow Tayebati et al.   CURRENT NEUROVASCULAR RESEARCH

Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors

(2011) Estefanía P Bello et al.   NATURE NEUROSCIENCE

Intracerebroventricular Leptin Infusion Improves Glucose Homeostasis in Lean Type 2 Diabetic MKR Mice via Hepatic Vagal and Non-Vagal Mechanisms

(2011) Xiaosong Li et al.   PLoS One

Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: An animal model

(2011) Margaret Hahn et al.   SCHIZOPHRENIA RESEARCH

Disruption of the Dopamine D2 Receptor Impairs Insulin Secretion and Causes Glucose Intolerance

(2010) Isabel García-Tornadú et al.   ENDOCRINOLOGY

New Insights into the Endocrine and Metabolic Roles of Dopamine D2 Receptors Gained from the Drd2–/– Mouse

(2010) Isabel Garcia-Tornadú et al.   NEUROENDOCRINOLOGY

Signaling pathways in schizophrenia: emerging targets and therapeutic strategies

(2010) Caline S. Karam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A Practical Guide to Rodent Islet Isolation and Assessment

(2009) Jeffrey D. Carter et al.   BIOLOGICAL PROCEDURES ONLINE

N-(4-(4-(2,3-Dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with Functionalized Linking Chains as High Affinity and Enantioselective D3 Receptor Antagonists∥⊥

(2009) Amy Hauck Newman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Impact of D2 Receptor Internalization on Binding Affinity of Neuroimaging Radiotracers

(2009) Ningning Guo et al.   NEUROPSYCHOPHARMACOLOGY

Signaling cascade of insulin-induced stimulation of l-dopa uptake in renal proximal tubule cells

(2008) Andrea Carranza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Granule docking and cargo release in pancreatic β-cells

(2008) Sebastian Barg et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Dopamine, kidney, and hypertension: studies in dopamine receptor knockout mice

(2008) Xiaoyan Wang et al.   PEDIATRIC NEPHROLOGY

Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice

(2007) Chunyu Zeng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY