Isoquercitrin Attenuated Cardiac Dysfunction Via AMPKα-Dependent Pathways in LPS-Treated Mice

Protectin DX attenuates LPS-induced inflammation and insulin resistance in adipocytes via AMPK-mediated suppression of the NFκB pathway

(2018) Tae Woo Jung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Enhancing Recovery From Sepsis

(2018) Hallie C. Prescott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Apoptosis triggered by isoquercitrin in bladder cancer cells by activating the AMPK-activated protein kinase pathway

(2017) Ping Wu et al.   Food & Function

Antioxidant Activity of Quercetin and Its Glucosides from Propolis: A Theoretical Study

(2017) Yan-Zhen Zheng et al.   Scientific Reports

Acute effects of quercetin-3-O-glucoside on endothelial function and blood pressure: a randomized dose-response study

(2016) Nicola P Bondonno et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Protection against cardiac hypertrophy by geniposide involves the GLP-1 receptor / AMPKα signalling pathway

(2016) Zhen-Guo Ma et al.   BRITISH JOURNAL OF PHARMACOLOGY

Lipid Use and Misuse by the Heart

(2016) P. Christian Schulze et al.   CIRCULATION RESEARCH

Cardioprotective effect of metformin in lipopolysaccharide-induced sepsis via suppression of toll-like receptor 4 (TLR4) in heart

(2016) Haleh Vaez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Development of an antioxidant biomaterial by promoting the deglycosylation of rutin to isoquercetin and quercetin

(2016) Johana M. Cruz-Zúñiga et al.   FOOD CHEMISTRY

AMPK activation by metformin inhibits local innate immune responses in the isolated rat heart by suppression of TLR 4-related pathway

(2016) Haleh Vaez et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hepatoprotective effect of isoquercitrin against acetaminophen-induced liver injury

(2016) Wenyan Xie et al.   LIFE SCIENCES

Resveratrol supplement inhibited the NF-κB inflammation pathway through activating AMPKα-SIRT1 pathway in mice with fatty liver

(2016) Yueli Tian et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial

(2015) James I Dower et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Cathepsin B deficiency attenuates cardiac remodeling in response to pressure overload via TNF-α/ASK1/JNK pathway

(2015) Qing-Qing Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance

(2015) Lawrence M. House et al.   Cardiovascular Diabetology

Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac FunctionNovelty and Significance

(2015) Konstantinos Drosatos et al.   CIRCULATION RESEARCH

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(2015) Nikhil Mulchandani et al.   MOLECULAR MEDICINE

Difference in protective effects of three structurally similar flavonoid glycosides from Hypericum ascyron against H2O2-induced injury in H9c2 cardiomyoblasts

(2015) XIU-MEI LI et al.   Molecular Medicine Reports

Quercetin oppositely regulates insulin-mediated glucose disposal in skeletal muscle under normal and inflammatory conditions: The dual roles of AMPK activation

(2015) Kang Liu et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Isoquercitrin activates the AMP–activated protein kinase (AMPK) signal pathway in rat H4IIE cells

(2014) Jingxin Zhou et al.   BMC Complementary and Alternative Medicine

Isoquercitrin: Pharmacology, toxicology, and metabolism

(2014) Kateřina Valentová et al.   FOOD AND CHEMICAL TOXICOLOGY

Understanding cardiac failure in sepsis

(2014) Antoine Vieillard-Baron et al.   INTENSIVE CARE MEDICINE

Isoquercitrin Suppresses Colon Cancer Cell Growthin Vitroby Targeting the Wnt/β-Catenin Signaling Pathway

(2014) Nathália G. Amado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review

(2014) Bogna Grygiel-Górniak   Nutrition Journal

Isoquercitrin inhibits the progression of liver cancer in vivo and in vitro via the MAPK signalling pathway

(2014) GUIHONG HUANG et al.   ONCOLOGY REPORTS

Reduced Oxidative Stress Contributes to the Lipid Lowering Effects of Isoquercitrin in Free Fatty Acids Induced Hepatocytes

(2014) Waseem Hassan et al.   Oxidative Medicine and Cellular Longevity

Inhibition of AMP-Activated Protein Kinase Accentuates Lipopolysaccharide-Induced Lung Endothelial Barrier Dysfunction and Lung Injury in Vivo

(2013) Junjie Xing et al.   AMERICAN JOURNAL OF PATHOLOGY

Peroxisome Proliferator–Activated Receptor-γ Activation Prevents Sepsis-Related Cardiac Dysfunction and Mortality In Mice

(2013) Konstantinos Drosatos et al.   Circulation-Heart Failure

Quercetin and quercetin-3-O-glucuronide are equally effective in ameliorating endothelial insulin resistance through inhibition of reactive oxygen species-associated inflammation

(2013) Xu-Dan Guo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Chlorogenic Acid and Rutin Play a Major Role in the In Vivo Anti-Diabetic Activity of Morus alba Leaf Extract on Type II Diabetic Rats

(2012) Attila Hunyadi et al.   PLoS One

Toll-Like Receptor-Mediated Inflammatory Signaling Reprograms Cardiac Energy Metabolism by Repressing Peroxisome Proliferator-Activated Receptor γ Coactivator-1 Signaling

(2011) Joel Schilling et al.   Circulation-Heart Failure

Inhibition of c-Jun-N-terminal Kinase Increases Cardiac Peroxisome Proliferator-activated Receptor α Expression and Fatty Acid Oxidation and Prevents Lipopolysaccharide-induced Heart Dysfunction

(2011) Konstantinos Drosatos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-кB activation via inhibition of IкB kinase activation

(2011) Jianli Niu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

In vivo antioxidative effect of isoquercitrin on cadmium-induced oxidative damage to mouse liver and kidney

(2011) Ruijin Li et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Antihypertensive effects of isoquercitrin and extracts from Tropaeolum majus L.: Evidence for the inhibition of angiotensin converting enzyme

(2010) Arquimedes Gasparotto Junior et al.   JOURNAL OF ETHNOPHARMACOLOGY

Metformin Prevents Progression of Heart Failure in Dogs

(2009) Hideyuki Sasaki et al.   CIRCULATION

Effects of hyperin, isoquercitrin and quercetin on lipopolysaccharide-induced nitrite production in rat peritoneal macrophages

(2008) Sanghyun Lee et al.   PHYTOTHERAPY RESEARCH