Nuclear Phosphatidylinositol 5-Phosphatase Is Essential for Allelic Exclusion of Variant Surface Glycoprotein Genes in Trypanosomes

Transcriptional Regulation of Telomeric Expression Sites and Antigenic Variation in Trypanosomes

(2018) Igor Cestari et al.   CURRENT GENOMICS

Inositol polyphosphate multikinase regulation of Trypanosoma brucei life stage development

(2018) Igor Cestari et al.   MOLECULAR BIOLOGY OF THE CELL

The Canonical Poly (A) Polymerase PAP1 Polyadenylates Non-Coding RNAs and Is Essential for snoRNA Biogenesis in Trypanosoma brucei

(2017) Vaibhav Chikne et al.   JOURNAL OF MOLECULAR BIOLOGY

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

(2017) Samuel Dean et al.   TRENDS IN PARASITOLOGY

Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression

(2016) Luke Maishman et al.   NUCLEIC ACIDS RESEARCH

VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

(2016) Lucy Glover et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Base J and H3.V Regulate Transcriptional Termination in Trypanosoma brucei

(2016) Danae Schulz et al.   PLoS Genetics

Identification of the ISWI Chromatin Remodeling Complex of the Early Branching EukaryoteTrypanosoma brucei

(2015) Tara Stanne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inositol phosphate pathway controls transcription of telomeric expression sites in trypanosomes

(2015) Igor Cestari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trans-Proteomic Pipeline, a standardized data processing pipeline for large-scale reproducible proteomics informatics

(2015) Eric W. Deutsch et al.   Proteomics Clinical Applications

The in vivo dynamics of antigenic variation in Trypanosoma brucei

(2015) M. R. Mugnier et al.   SCIENCE

Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome

(2015) Danae Schulz et al.   PLOS BIOLOGY

The bi-lobe-associated LRRP1 regulates Ran activity in Trypanosoma brucei

(2014) A. Brasseur et al.   JOURNAL OF CELL SCIENCE

Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427

(2014) George A.M. Cross et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Suppression of subtelomeric VSG switching by Trypanosoma brucei TRF requires its TTAGGG repeat-binding activity

(2014) Sanaa E. Jehi et al.   NUCLEIC ACIDS RESEARCH

Transcription is initiated on silent variant surface glycoprotein expression sites despite monoallelic expression in Trypanosoma brucei

(2014) A. Kassem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The signaling phospholipid PIP3creates a new interaction surface on the nuclear receptor SF-1

(2014) Raymond D. Blind et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Phosphoinositide Substrate Recognition, Catalysis, and Membrane Interactions in Human Inositol Polyphosphate 5-Phosphatases

(2014) Lionel Trésaugues et al.   STRUCTURE

SUMOylation by the E3 Ligase TbSIZ1/PIAS1 Positively Regulates VSG Expression in Trypanosoma brucei

(2014) Diana López-Farfán et al.   PLoS Pathogens

Inhibition of Isoleucyl-tRNA Synthetase as a Potential Treatment for Human African Trypanosomiasis

(2013) Igor Cestari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trypanosome cdc2-Related Kinase 9 Controls Spliced Leader RNA cap4 Methylation and Phosphorylation of RNA Polymerase II Subunit RPB1

(2013) N. Badjatia et al.   MOLECULAR AND CELLULAR BIOLOGY

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

(2013) Christopher J. Millard et al.   MOLECULAR CELL

TDP1 is an HMG chromatin protein facilitating RNA polymerase I transcription in African trypanosomes

(2013) Mani Shankar Narayanan et al.   NUCLEIC ACIDS RESEARCH

Silencing subtelomeric VSGs by Trypanosoma brucei RAP1 at the insect stage involves chromatin structure changes

(2013) Unnati M. Pandya et al.   NUCLEIC ACIDS RESEARCH

Promoter occupancy of the basal class I transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei

(2013) T. N. Nguyen et al.   NUCLEIC ACIDS RESEARCH

Trypanosoma bruceiOrc1 is essential for nuclear DNA replication and affects bothVSGsilencing andVSGswitching

(2012) Imaan Benmerzouga et al.   MOLECULAR MICROBIOLOGY

Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei

(2012) Sam Alsford et al.   NUCLEIC ACIDS RESEARCH

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Protocol: Chromatin immunoprecipitation (ChIP) methodology to investigate histone modifications in two model diatom species

(2012) Xin Lin et al.   Plant Methods

NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions

(2012) Kelly N. DuBois et al.   PLOS BIOLOGY

Histone H1 Plays a Role in Heterochromatin Formation and VSG Expression Site Silencing in Trypanosoma brucei

(2012) Megan L. Povelones et al.   PLoS Pathogens

Spliced Leader Trapping Reveals Widespread Alternative Splicing Patterns in the Highly Dynamic Transcriptome of Trypanosoma brucei

(2010) Daniel Nilsson et al.   PLoS Pathogens

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

CRK9 contributes to regulation of mitosis and cytokinesis in the procyclic form of Trypanosoma brucei

(2009) Stephane Gourguechon et al.   BMC CELL BIOLOGY

RAP1 Is Essential for Silencing Telomeric Variant Surface Glycoprotein Genes in Trypanosoma brucei

(2009) Xiaofeng Yang et al.   CELL

ActiveVSGExpression Sites inTrypanosoma bruceiAre Depleted of Nucleosomes

(2009) Tara M. Stanne et al.   EUKARYOTIC CELL

Nucleosomes Are Depleted at theVSGExpression Site Transcribed by RNA Polymerase I in African Trypanosomes

(2009) Luisa M. Figueiredo et al.   EUKARYOTIC CELL

Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor

(2009) Jeffrey A. DeGrasse et al.   MOLECULAR & CELLULAR PROTEOMICS

Functional characterization and protein–protein interactions of trypanosome splicing factors U2AF35, U2AF65 and SF1

(2009) Martin P. Vazquez et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Label-free, normalized quantification of complex mass spectrometry data for proteomic analysis

(2009) Noelle M Griffin et al.   NATURE BIOTECHNOLOGY

A Histone Methyltransferase Modulates Antigenic Variation in African Trypanosomes

(2008) Luisa M Figueiredo et al.   PLOS BIOLOGY