Trypanosoma bruceiOrc1 is essential for nuclear DNA replication and affects bothVSGsilencing andVSGswitching

From yeast to mammals: Recent advances in genetic control of homologous recombination

(2012) Yoav Karpenshif et al.   DNA REPAIR

Cohesin Association to Replication Sites Depends on Rad50 and Promotes Fork Restart

(2012) Mireille Tittel-Elmer et al.   MOLECULAR CELL

The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing

(2012) Abhijit S. Deshmukh et al.   NUCLEIC ACIDS RESEARCH

Identification of ORC1/CDC6-Interacting Factors in Trypanosoma brucei Reveals Critical Features of Origin Recognition Complex Architecture

(2012) Calvin Tiengwe et al.   PLoS One

Genome-wide Analysis Reveals Extensive Functional Interaction between DNA Replication Initiation and Transcription in the Genome of Trypanosoma brucei

(2012) Calvin Tiengwe et al.   Cell Reports

NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions

(2012) Kelly N. DuBois et al.   PLOS BIOLOGY

“ORCanization” on heterochromatin: Linking DNA replication initiation to chromatin organization

(2011) Arindam Chakraborty et al.   Epigenetics

The Cdc45·Mcm2–7·GINS Protein Complex in Trypanosomes Regulates DNA Replication and Interacts with Two Orc1-like Proteins in the Origin Recognition Complex

(2011) Hung Quang Dang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Trypanosoma brucei RMI1/BLAP75 Homologue and Its Roles in Antigenic Variation

(2011) Hee-Sook Kim et al.   PLoS One

Epigenetics and transcriptional control in African trypanosomes

(2010) Gloria Rudenko   Essays in Biochemistry

Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes

(2010) Qiao-Ping Wang et al.   MOLECULAR MICROBIOLOGY

The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei

(2010) Viola Denninger et al.   MOLECULAR MICROBIOLOGY

Eukaryotic DNA replication origins: many choices for appropriate answers

(2010) Marcel Méchali   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NLP is a novel transcription regulator involved in VSG expression site control in Trypanosoma brucei

(2010) Mani Shankar Narayanan et al.   NUCLEIC ACIDS RESEARCH

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization

(2010) S. G. Prasanth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TOPO3α Influences Antigenic Variation by Monitoring Expression-Site-Associated VSG Switching in Trypanosoma brucei

(2010) Hee-Sook Kim et al.   PLoS Pathogens

RAP1 Is Essential for Silencing Telomeric Variant Surface Glycoprotein Genes in Trypanosoma brucei

(2009) Xiaofeng Yang et al.   CELL

Trypanosome Prereplication Machinery Contains a Single Functional Orc1/Cdc6 Protein, Which Is Typical ofArchaea

(2009) Patrícia Diogo de Melo Godoy et al.   EUKARYOTIC CELL

ActiveVSGExpression Sites inTrypanosoma bruceiAre Depleted of Nucleosomes

(2009) Tara M. Stanne et al.   EUKARYOTIC CELL

Nucleosomes Are Depleted at theVSGExpression Site Transcribed by RNA Polymerase I in African Trypanosomes

(2009) Luisa M. Figueiredo et al.   EUKARYOTIC CELL

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

(2009) T. N. Siegel et al.   GENES & DEVELOPMENT

Cohesin regulatesVSGmonoallelic expression in trypanosomes

(2009) David Landeira et al.   JOURNAL OF CELL BIOLOGY

Isolation of active regulatory elements from eukaryotic chromatin using FAIRE (Formaldehyde Assisted Isolation of Regulatory Elements)

(2009) Paul G. Giresi et al.   METHODS

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei

(2009) Catharine E. Boothroyd et al.   NATURE

Stem-Loop Silencing Reveals that a Third Mitochondrial DNA Polymerase, POLID, Is Required for Kinetoplast DNA Replication in Trypanosomes

(2008) Julian Chandler et al.   EUKARYOTIC CELL

Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres

(2008) Yasutoshi Tatsumi et al.   GENES TO CELLS

Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum

(2008) L. Mancio-Silva et al.   JOURNAL OF CELL SCIENCE

Trypanosoma brucei BRCA2 acts in antigenic variation and has undergone a recent expansion in BRC repeat number that is important during homologous recombination

(2008) Claire L. Hartley et al.   MOLECULAR MICROBIOLOGY

Telomeric Expression Sites Are Highly Conserved in Trypanosoma brucei

(2008) Christiane Hertz-Fowler et al.   PLoS One

A Histone Methyltransferase Modulates Antigenic Variation in African Trypanosomes

(2008) Luisa M Figueiredo et al.   PLOS BIOLOGY