Particle squeezing in narrow confinements

Label-free sorting of soft microparticles using a bioinspired synthetic cilia array

(2018) Salman Sohrabi et al.   Biomicrofluidics

Hydrodynamic mobility of confined polymeric particles, vesicles, and cancer cells in a square microchannel

(2018) Shamim M. Ahmmed et al.   Biomicrofluidics

High-purity capture of CTCs based on micro-beads enhanced isolation by size of epithelial tumor cells (ISET) method

(2018) Na Sun et al.   BIOSENSORS & BIOELECTRONICS

Three-dimensional simulation of droplet dynamics in planar contraction microchannel

(2018) Van Thanh Hoang et al.   CHEMICAL ENGINEERING SCIENCE

Dynamics of capsules enclosing viscoelastic fluid in simple shear flow

(2018) Zheng Yuan Luo et al.   JOURNAL OF FLUID MECHANICS

Design of Nanofibrous and Microfibrous Channels for Fast Capillary Flow

(2018) Dahua Shou et al.   LANGMUIR

A parallel fluid–solid coupling model using LAMMPS and Palabos based on the immersed boundary method

(2018) Jifu Tan et al.   Journal of Computational Science

On passing a non-Newtonian circulating tumor cell (CTC) through a deformation-based microfluidic chip

(2018) Xiaolong Zhang et al.   THEORETICAL AND COMPUTATIONAL FLUID DYNAMICS

An Inertia-Deformability Hybrid Circulating Tumor Cell Chip: Design, Clinical Test, and Numerical Analysis

(2018) Hongmei Chen et al.   Journal of Medical Devices-Transactions of the ASME

Constricted channel flow with different cross-section shapes

(2017) A. Van Hirtum et al.   EUROPEAN JOURNAL OF MECHANICS B-FLUIDS

The porous media's effect on the permeation of elastic (soft) particles

(2017) Eduard Benet et al.   JOURNAL OF MEMBRANE SCIENCE

On the thin-film-dominated passing pressure of cancer cell squeezing through a microfluidic CTC chip

(2017) Xiaolong Zhang et al.   Microfluidics and Nanofluidics

Arch-like microsorters with multi-modal and clogging-improved filtering functions by using femtosecond laser multifocal parallel microfabrication

(2017) Bing Xu et al.   OPTICS EXPRESS

A numerical procedure for scaling droplet deformation in a microfluidic expansion channel

(2017) Erfan Kadivar et al.   PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS

Droplet squeezing through a narrow constriction: Minimum impulse and critical velocity

(2017) Zhifeng Zhang et al.   PHYSICS OF FLUIDS

Effect of internal architecture on microgel deformation in microfluidic constrictions

(2017) Lynna Chen et al.   Soft Matter

Squeezing bio-capsules into a constriction: deformation till break-up

(2017) Anne Le Goff et al.   Soft Matter

Clogging of microfluidic systems

(2017) Emilie Dressaire et al.   Soft Matter

Influence of surface tension in the surfactant-driven fracture of closely-packed particulate monolayers

(2017) Christian Peco et al.   Soft Matter

Off-center motion of a trapped elastic capsule in a microfluidic channel with a narrow constriction

(2017) Zheng Yuan Luo et al.   Soft Matter

The Optimization of a Microfluidic CTC Filtering Chip by Simulation

(2017) Huan Li et al.   Micromachines

Fluid Flow and Mixing Induced by AC Continuous Electrowetting of Liquid Metal Droplet

(2017) Qingming Hu et al.   Micromachines

Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca2+-mediated Adaptations

(2017) Jens G. Danielczok et al.   Frontiers in Physiology

Single-Cell Mechanical Characteristics Analyzed by Multiconstriction Microfluidic Channels

(2017) Xiang Ren et al.   ACS Sensors

Active elastohydrodynamics of vesicles in narrow blind constrictions

(2017) T. G. Fai et al.   Physical Review Fluids

Clustering of microscopic particles in constricted blood flow

(2017) Christian Bächer et al.   Physical Review Fluids

Mechanical diagnosis of human erythrocytes by ultra-high speed manipulation unraveled critical time window for global cytoskeletal remodeling

(2017) Hiroaki Ito et al.   Scientific Reports

Highly-sensitive capture of circulating tumor cells using micro-ellipse filters

(2017) Hongmei Chen et al.   Scientific Reports

Numerical simulation of a single cell passing through a narrow slit

(2016) L. L. Xiao et al.   Biomechanics and Modeling in Mechanobiology

Three-dimensional simulation of micrometer-sized droplet impact and penetration into the powder bed

(2016) Hua Tan   CHEMICAL ENGINEERING SCIENCE

Squish and squeeze — the nucleus as a physical barrier during migration in confined environments

(2016) Alexandra Lynn McGregor et al.   CURRENT OPINION IN CELL BIOLOGY

Soft matter physics: Tools and mechanical models for living cellular aggregates

(2016) Nada Khalifat et al.   JAPANESE JOURNAL OF APPLIED PHYSICS

Particle-based simulations of red blood cells—A review

(2016) Ting Ye et al.   JOURNAL OF BIOMECHANICS

Confinement and viscosity ratio effect on droplet break-up in a concentrated emulsion flowing through a narrow constriction

(2016) Ya Gai et al.   LAB ON A CHIP

Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum

(2016) Quan Guo et al.   LAB ON A CHIP

Clogging in parallelized tapered microfluidic channels

(2016) Sorell S. Massenburg et al.   Microfluidics and Nanofluidics

In vitro and ex vivo strategies for intracellular delivery

(2016) Martin P. Stewart et al.   NATURE

A computational study of two-phase viscoelastic systems in a capillary tube with a sudden contraction/expansion

(2016) Daulet Izbassarov et al.   PHYSICS OF FLUIDS

Biomechanics of red blood cells in human spleen and consequences for physiology and disease

(2016) Igor V. Pivkin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pipette aspiration testing of soft tissues: the elastic half-space model revisited

(2016) Ivan Argatov et al.   PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Sub-cellular modeling of platelet transport in blood flow through microchannels with constriction

(2016) Alireza Yazdani et al.   Soft Matter

Live-cell protein labelling with nanometre precision by cell squeezing

(2016) Alina Kollmannsperger et al.   Nature Communications

Bacteria Delay the Jamming of Particles at Microchannel Bottlenecks

(2016) Zenamarkos Bantie Sendekie et al.   Scientific Reports

Single-Sided Digital Microfluidic (SDMF) Devices for Effective Coolant Delivery and Enhanced Two-Phase Cooling

(2016) Sung-Yong Park et al.   Micromachines

Coalescence of droplets due to a constant force interaction in a quiescent viscous fluid

(2016) John M. Frostad et al.   Physical Review Fluids

Single-Cell Electrical Phenotyping Enabling the Classification of Mouse Tumor Samples

(2016) Yang Zhao et al.   Scientific Reports

Microfluidic Magnetic Bead Assay for Cell Detection

(2015) Fan Liu et al.   ANALYTICAL CHEMISTRY

Deformability-based circulating tumor cell separation with conical-shaped microfilters: Concept, optimization, and design criteria

(2015) Mohammad Aghaamoo et al.   Biomicrofluidics

On-chip actuation transmitter for enhancing the dynamic response of cell manipulation using a macro-scale pump

(2015) Takumi Monzawa et al.   Biomicrofluidics

Entry effects of droplet in a micro confinement: Implications for deformation-based circulating tumor cell microfiltration

(2015) Zhifeng Zhang et al.   Biomicrofluidics

Cell Mechanics: Combining Speed with Precision

(2015) Hans M. Wyss   BIOPHYSICAL JOURNAL

Microconstriction Arrays for High-Throughput Quantitative Measurements of Cell Mechanical Properties

(2015) Janina R. Lange et al.   BIOPHYSICAL JOURNAL

Migration in Confined 3D Environments Is Determined by a Combination of Adhesiveness, Nuclear Volume, Contractility, and Cell Stiffness

(2015) Lena A. Lautscham et al.   BIOPHYSICAL JOURNAL

In-Channel Constriction Valve for Cerebrospinal Fluid Sampling

(2015) Stefano Facchin et al.   IEEE TRANSACTIONS ON MAGNETICS

An optofluidic constriction chip for monitoring metastatic potential and drug response of cancer cells

(2015) R. Martinez Vazquez et al.   Integrative Biology

Separation and sorting of cells in microsystems using physical principles

(2015) Gi-Hun Lee et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Directional, passive liquid transport: the Texas horned lizard as a model for a biomimetic ‘liquid diode’

(2015) Philipp Comanns et al.   Journal of the Royal Society Interface

Multiplexed fluidic plunger mechanism for the measurement of red blood cell deformability

(2015) Marie-Eve Myrand-Lapierre et al.   LAB ON A CHIP

Microfluidic Investigation of Nanoparticles’ Role in Mobilizing Trapped Oil Droplets in Porous Media

(2015) Ke Xu et al.   LANGMUIR

Minimum applied pressure for a drop through an abruptly constricted capillary

(2015) Mingchao Liang et al.   Microfluidics and Nanofluidics

Deformation of a single mouse oocyte in a constricted microfluidic channel

(2015) ZhengYuan Luo et al.   Microfluidics and Nanofluidics

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

(2015) A Fatih Sarioglu et al.   NATURE METHODS

Structural optimization of porous media for fast and controlled capillary flows

(2015) Dahua Shou et al.   PHYSICAL REVIEW E

Simultaneous Characterization of Instantaneous Young’s Modulus and Specific Membrane Capacitance of Single Cells Using a Microfluidic System

(2015) Yang Zhao et al.   SENSORS

Probing Cell Deformability via Acoustically Actuated Bubbles

(2015) Yuliang Xie et al.   Small

Bio-Pick, Place, and Perfuse: A New Instrument for Three-Dimensional Tissue Engineering

(2015) Andrew M. Blakely et al.   TISSUE ENGINEERING PART C-METHODS

IRSp53 senses negative membrane curvature and phase separates along membrane tubules

(2015) Coline Prévost et al.   Nature Communications

Bioinspired membrane-based systems for a physical approach of cell organization and dynamics: usefulness and limitations

(2015) T. J. Lagny et al.   Interface Focus

Universal behavior of hydrogels confined to narrow capillaries

(2015) Yang Li et al.   Scientific Reports

Constriction Channel Based Single-Cell Mechanical Property Characterization

(2015) Chengcheng Xue et al.   Micromachines

CRISPR-Cas9 delivery to hard-to-transfect cells via membrane deformation

(2015) X. Han et al.   Science Advances

The fastest capillary flow under gravity

(2014) Dahua Shou et al.   APPLIED PHYSICS LETTERS

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Droplet formation via squeezing mechanism in a microfluidic flow-focusing device

(2014) Amit Gupta et al.   COMPUTERS & FLUIDS

High-Throughput Immunomagnetic Cell Detection Using a Microaperture Chip System

(2014) Chun-Li Chang et al.   IEEE SENSORS JOURNAL

A New Dimensionless Index for Evaluating Cell Stiffness-Based Deformability in Microchannel

(2014) Chia-Hung Dylan Tsai et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Dynamics of a compound droplet in shear flow

(2014) Haobo Hua et al.   INTERNATIONAL JOURNAL OF HEAT AND FLUID FLOW

Red blood cell fatigue evaluation based on the close-encountering point between extensibility and recoverability

(2014) Shinya Sakuma et al.   LAB ON A CHIP

The effects of 3D channel geometry on CTC passing pressure – towards deformability-based cancer cell separation

(2014) Zhifeng Zhang et al.   LAB ON A CHIP

Rare cell isolation and analysis in microfluidics

(2014) Yuchao Chen et al.   LAB ON A CHIP

Geometry-Induced Asymmetric Capillary Flow

(2014) Dahua Shou et al.   LANGMUIR

Probing red blood cell mechanics, rheology and dynamics with a two-component multi-scale model

(2014) X. Li et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Treelike networks accelerating capillary flow

(2014) Dahua Shou et al.   PHYSICAL REVIEW E

Forced transport of deformable containers through narrow constrictions

(2014) Remy Kusters et al.   PHYSICAL REVIEW E

A constriction channel based microfluidic system enabling continuous characterization of cellular instantaneous Young's modulus

(2014) Y.N. Luo et al.   SENSORS AND ACTUATORS B-CHEMICAL

Rheology of red blood cells under flow in highly confined microchannels. II. Effect of focusing and confinement

(2014) Guillermo R. Lázaro et al.   Soft Matter

Microfluidic Dynamic Interfacial Tensiometry (μDIT)

(2014) Quentin Brosseau et al.   Soft Matter

Capillary micromechanics for core–shell particles

(2014) Tiantian Kong et al.   Soft Matter

Quantification of surface tension and internal pressure generated by single mitotic cells

(2014) Elisabeth Fischer-Friedrich et al.   Scientific Reports

Translocation of flexible polymersomes across pores at the nanoscale

(2014) Carla Pegoraro et al.   Biomaterials Science

Automated Micropipette Aspiration of Single Cells

(2013) Ehsan Shojaei-Baghini et al.   ANNALS OF BIOMEDICAL ENGINEERING

Simulation of malaria-infected red blood cells in microfluidic channels: Passage and blockage

(2013) Tenghu Wu et al.   Biomicrofluidics

Highly selective biomechanical separation of cancer cells from leukocytes using microfluidic ratchets and hydrodynamic concentrator

(2013) Bill K. Lin et al.   Biomicrofluidics

Detection and recovery of circulating colon cancer cells using a dielectrophoresis-based device: KRAS mutation status in pure CTCs

(2013) Francesco Fabbri et al.   CANCER LETTERS

Flow of a drop through a constricted microcapillary

(2013) J.F. Roca et al.   COMPUTERS & FLUIDS

Effect of microfiltration concentration factor on serum protein removal from skim milk using spiral-wound polymeric membranes1

(2013) S.L. Beckman et al.   JOURNAL OF DAIRY SCIENCE

Technologies for detection of circulating tumor cells: facts and vision

(2013) Catherine Alix-Panabières et al.   LAB ON A CHIP

Optimal Design of Porous Structures for the Fastest Liquid Absorption

(2013) Dahua Shou et al.   LANGMUIR

Numerical Simulation of Passage of a Neutrophil through a Rectangular Channel with a Moderate Constriction

(2013) Atsushi Shirai et al.   PLoS One

Characterizing deformability and surface friction of cancer cells

(2013) S. Byun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A vector-free microfluidic platform for intracellular delivery

(2013) A. Sharei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transient dynamics of an elastic capsule in a microfluidic constriction

(2013) Sun-Young Park et al.   Soft Matter

Break-up of droplets in a concentrated emulsion flowing through a narrow constriction

(2013) Liat Rosenfeld et al.   Soft Matter

Spontaneous electrical charging of droplets by conventional pipetting

(2013) Dongwhi Choi et al.   Scientific Reports

Detecting Circulating Tumor Cells: Current Challenges and New Trends

(2013) Bin Hong et al.   Theranostics

Simulations of gravity-induced trapping of a deformable drop in a three-dimensional constriction

(2012) Thomas Ratcliffe et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Effects of crossflow velocity and transmembrane pressure on microfiltration of oil-in-water emulsions

(2012) Tohid Darvishzadeh et al.   JOURNAL OF MEMBRANE SCIENCE

Microfluidic micropipette aspiration for measuring the deformability of single cells

(2012) Quan Guo et al.   LAB ON A CHIP

High-throughput biophysical measurement of human red blood cells

(2012) Yi Zheng et al.   LAB ON A CHIP

Shape Deformation and Recovery of Multilayer Microcapsules after Being Squeezed through a Microchannel

(2012) Shupeng She et al.   LANGMUIR

Numerical modeling of multiphase flows in microfluidics and micro process engineering: a review of methods and applications

(2012) Martin Wörner   Microfluidics and Nanofluidics

Shape-shifting gametocytes: how and why does P. falciparum go banana-shaped?

(2012) Matthew W.A. Dixon et al.   TRENDS IN PARASITOLOGY

Direct pore-level observation of permeability increase in two-phase flow by shaking

(2011) Igor Beresnev et al.   GEOPHYSICAL RESEARCH LETTERS

Evidence for active control of perfusion within lung microvessels

(2011) Kal E. Watson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Flow of a spherical capsule in a pore with circular or square cross-section

(2011) X.-Q. Hu et al.   JOURNAL OF FLUID MECHANICS

A microfabricated deformability-based flow cytometer with application to malaria

(2011) Hansen Bow et al.   LAB ON A CHIP

Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells

(2011) Jian Chen et al.   LAB ON A CHIP

Deterministic microfluidic ratchet based on the deformation of individual cells

(2011) Quan Guo et al.   PHYSICAL REVIEW E

The effect of confinement-induced shear on drop deformation and breakup in microfluidic extensional flows

(2011) Molly K. Mulligan et al.   PHYSICS OF FLUIDS

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Droplet based microfluidics

(2011) Ralf Seemann et al.   REPORTS ON PROGRESS IN PHYSICS

Arrested coalescence in Pickering emulsions

(2011) Amar B. Pawar et al.   Soft Matter

Crystallization and intermittent dynamics in constricted microfluidic flows of dense suspensions

(2011) Damiano Genovese et al.   Soft Matter

Microgel Translocation through Pores under Confinement

(2010) Grant R. Hendrickson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modeling cell entry into a micro-channel

(2010) Fong Yew Leong et al.   Biomechanics and Modeling in Mechanobiology

Viscosity effects in vibratory mobilization of residual oil

(2010) Igor A. Beresnev et al.   GEOPHYSICS

Droplet dynamics passing through obstructions in confined microchannel flow

(2010) Changkwon Chung et al.   Microfluidics and Nanofluidics

Uptake and withdrawal of droplets from carbon nanotubes

(2010) D. Schebarchov et al.   Nanoscale

Aspiration of Biological Viscoelastic Drops

(2010) Karine Guevorkian et al.   PHYSICAL REVIEW LETTERS

Buoyancy-induced squeezing of a deformable drop through an axisymmetric ring constriction

(2010) Thomas Ratcliffe et al.   PHYSICS OF FLUIDS

Impact of a compound droplet on a flat surface: A model for single cell epitaxy

(2010) Savas Tasoglu et al.   PHYSICS OF FLUIDS

Confinement Regulates Complex Biochemical Networks: Initiation of Blood Clotting by “Diffusion Acting”

(2009) Feng Shen et al.   BIOPHYSICAL JOURNAL

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Red blood cell deformation in microconfined flow

(2009) Giovanna Tomaiuolo et al.   Soft Matter

Designing microfluidic channel that separates elastic particles upon stiffness

(2009) John P. Arata et al.   Soft Matter

Condition for Break-up of Non-Wetting Fluids in Sinusoidally Constricted Capillary Channels

(2009) Igor A. Beresnev et al.   TRANSPORT IN POROUS MEDIA

Cellular-scale hydrodynamics

(2008) Manouk Abkarian et al.   Biomedical Materials

Study of Impact-Induced Mechanical Effects in Cell Direct Writing Using Smooth Particle Hydrodynamic Method

(2008) Wei Wang et al.   JOURNAL OF MANUFACTURING SCIENCE AND ENGINEERING-TRANSACTIONS OF THE ASME

Drop on demand in a microfluidic chip

(2008) Jie Xu et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Deformation of a viscoelastic droplet passing through a microfluidic contraction

(2008) D.J.E. Harvie et al.   JOURNAL OF NON-NEWTONIAN FLUID MECHANICS

Numerical study on the effect of viscoelasticity on drop deformation in simple shear and 5:1:5 planar contraction/expansion microchannel

(2008) Changkwon Chung et al.   JOURNAL OF NON-NEWTONIAN FLUID MECHANICS

Simple, robust storage of drops and fluids in a microfluidic device

(2008) Hakim Boukellal et al.   LAB ON A CHIP

Squeezing of a periodic emulsion through a cubic lattice of spheres

(2008) Alexander Z. Zinchenko et al.   PHYSICS OF FLUIDS

Deformation of a compound drop through a contraction in a pressure-driven pipe flow

(2007) Chunfeng Zhou et al.   INTERNATIONAL JOURNAL OF MULTIPHASE FLOW