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Prevalence of K13 mutation and Day-3 positive parasitaemia in artemisinin-resistant malaria endemic area of Cambodia: a cross-sectional study

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Plasmodium falciparum K13 Mutations Differentially Impact Ozonide Susceptibility and Parasite Fitness In Vitro

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Cellular prion protein is present in mitochondria of healthy mice

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Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study

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Alternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity

(2016) Whitney A. Kite et al.   MALARIA JOURNAL

Lack of K13 mutations in Plasmodium falciparum persisting after artemisinin combination therapy treatment of Kenyan children

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Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border

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Polymorphisms in the K13-Propeller Gene in Artemisinin-Susceptible Plasmodium falciparum Parasites from Bougoula-Hameau and Bandiagara, Mali

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Lack of Artemisinin Resistance in Plasmodium falciparum in Uganda Based on Parasitological and Molecular Assays

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Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations

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A Kinase-Independent Role for EGF Receptor in Autophagy Initiation

(2015) Xiaojun Tan et al.   CELL

Autophagy Inhibition Overcomes the Antagonistic Effect Between Gefitinib and Cisplatin in Epidermal Growth Factor Receptor Mutant Non–Small-Cell Lung Cancer Cells

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WIPI proteins: essential PtdIns3P effectors at the nascent autophagosome

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PI(5)P Regulates Autophagosome Biogenesis

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

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Genetic architecture of artemisinin-resistant Plasmodium falciparum

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Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

(2015) Pedro Mejia et al.   Nature Communications

High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

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Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

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Flow Cytometry-Based Analysis of Artemisinin-Resistant Plasmodium falciparum in the Ring-Stage Survival Assay

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Mitochondrial KATP channel involvement in angiotensin II-induced autophagy in vascular smooth muscle cells

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Therapeutic potential of the dual EGFR/HER2 inhibitor AZD8931 in circumventing endocrine resistance

(2014) Gladys Morrison et al.   BREAST CANCER RESEARCH AND TREATMENT

Absence of Putative Artemisinin Resistance Mutations Among Plasmodium falciparum in Sub-Saharan Africa: A Molecular Epidemiologic Study

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Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

(2014) Mehdi Ghorbal et al.   NATURE BIOTECHNOLOGY

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

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K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates

(2014) J. Straimer et al.   SCIENCE

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

(2014) S. Mok et al.   SCIENCE

Ex VivoSusceptibility of Plasmodium falciparum to Antimalarial Drugs in Western, Northern, and Eastern Cambodia, 2011-2012: Association with Molecular Markers

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Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies

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Reduced Artemisinin Susceptibility of Plasmodium falciparum Ring Stages in Western Cambodia

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Mechanisms ofin vitroresistance to dihydroartemisinin inPlasmodium falciparum

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Mitochondrial Electron Transport Is the Cellular Target of the Oncology Drug Elesclomol

(2012) Ronald K. Blackman et al.   PLoS One

The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites

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Hallmarks of Cancer: The Next Generation

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Chemical Rescue of Malaria Parasites Lacking an Apicoplast Defines Organelle Function in Blood-Stage Plasmodium falciparum

(2011) Ellen Yeh et al.   PLOS BIOLOGY

Biological Actions of Artemisinin: Insights from Medicinal Chemistry Studies

(2010) Jian Li et al.   MOLECULES

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum

(2009) Jing Yuan et al.   Nature Chemical Biology

Elesclomol induces cancer cell apoptosis through oxidative stress

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