Foot-and-Mouth Disease Virus Leader Protease Cleaves G3BP1 and G3BP2 and Inhibits Stress Granule Formation

Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies

(2018) Kirby N. Swatek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Picornavirus 2A protease regulates stress granule formation to facilitate viral translation

(2018) Xiaodan Yang et al.   PLoS Pathogens

G3BP1 interacts directly with the FMDV IRES and negatively regulates translation

(2017) Alfonso Galan et al.   FEBS Journal

Enterovirus 71 suppresses interferon responses by blocking Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling through inducing karyopherin-α1 degradation

(2017) Chunyang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Function of Viral Deubiquitinating Enzymes

(2017) Ben A. Bailey-Elkin et al.   JOURNAL OF MOLECULAR BIOLOGY

Disruption of MDA5-Mediated Innate Immune Responses by the 3C Proteins of Coxsackievirus A16, Coxsackievirus A6, and Enterovirus D68

(2017) Yajuan Rui et al.   JOURNAL OF VIROLOGY

Foot-and-mouth disease virus induces lysosomal degradation of host protein kinase PKR by 3C proteinase to facilitate virus replication

(2017) Chuntian Li et al.   VIROLOGY

dsRNA Binding Domain of PKR Is Proteolytically Released by Enterovirus A71 to Facilitate Viral Replication

(2017) Yu-Hsiu Chang et al.   Frontiers in Cellular and Infection Microbiology

Enterovirus 71 induces anti-viral stress granule-like structures in RD cells

(2016) Yuanmei Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage

(2016) Majid N. Humoud et al.   JOURNAL OF VIROLOGY

The nuclear protein Sam68 is recruited to the cytoplasmic stress granules during enterovirus 71 infection

(2016) Hua Zhang et al.   MICROBIAL PATHOGENESIS

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

(2016) Huib H. Rabouw et al.   PLoS Pathogens

Dengue virus infection induces formation of G3BP1 granules in human lung epithelial cells

(2015) Jun Xia et al.   ARCHIVES OF VIROLOGY

Stress Granule Components G3BP1 and G3BP2 Play a Proviral Role Early in Chikungunya Virus Replication

(2015) Florine E. M. Scholte et al.   JOURNAL OF VIROLOGY

Analysis of the interaction between host factor Sam68 and viral elements during foot-and-mouth disease virus infections

(2015) Devendra K. Rai et al.   Virology Journal

Multiple Poliovirus Proteins Repress Cytoplasmic RNA Granules

(2015) Jonathan Dougherty et al.   Viruses-Basel

Stress Granules Regulate Double-Stranded RNA-Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1

(2015) Lucas C. Reineke et al.   mBio

Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids

(2014) Jiaxi Wu et al.   Annual Review of Immunology

Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases

(2014) Lonneke van der Linden et al.   ANTIVIRAL RESEARCH

Induction and suppression of innate antiviral responses by picornaviruses

(2014) Qian Feng et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Enterovirus 2Apro Targets MDA5 and MAVS in Infected Cells

(2014) Q. Feng et al.   JOURNAL OF VIROLOGY

3Cpro of Foot-and-Mouth Disease Virus Antagonizes the Interferon Signaling Pathway by Blocking STAT1/STAT2 Nuclear Translocation

(2014) Y. Du et al.   JOURNAL OF VIROLOGY

The Stress Granule Protein G3BP1 Recruits Protein Kinase R To Promote Multiple Innate Immune Antiviral Responses

(2014) Lucas C. Reineke et al.   JOURNAL OF VIROLOGY

G3BP1, G3BP2 and CAPRIN1 Are Required for Translation of Interferon Stimulated mRNAs and Are Targeted by a Dengue Virus Non-coding RNA

(2014) Katell Bidet et al.   PLoS Pathogens

A Novel, Broad-Spectrum Inhibitor of Enterovirus Replication That Targets Host Cell Factor Phosphatidylinositol 4-Kinase IIIβ

(2013) Hilde M. van der Schaar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Continuous Bovine Kidney Cell Line Constitutively Expressing Bovine  V 6 Integrin Has Increased Susceptibility to Foot-and-Mouth Disease Virus

(2013) M. LaRocco et al.   JOURNAL OF CLINICAL MICROBIOLOGY

MDA5 Localizes to Stress Granules, but This Localization Is Not Required for the Induction of Type I Interferon

(2013) M. A. Langereis et al.   JOURNAL OF VIROLOGY

Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses

(2013) C. S. Ng et al.   JOURNAL OF VIROLOGY

Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection

(2013) Gabriel Fung et al.   PLoS One

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Enterovirus 71 Protease 2Apro Targets MAVS to Inhibit Anti-Viral Type I Interferon Responses

(2013) Bei Wang et al.   PLoS Pathogens

Foot-and-Mouth Disease Virus 3C Protease Cleaves NEMO To Impair Innate Immune Signaling

(2012) D. Wang et al.   JOURNAL OF VIROLOGY

Chikungunya Virus nsP3 Blocks Stress Granule Assembly by Recruitment of G3BP into Cytoplasmic Foci

(2012) J. J. Fros et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus (HCV) Induces Formation of Stress Granules Whose Proteins Regulate HCV RNA Replication and Virus Assembly and Egress

(2012) U. Garaigorta et al.   JOURNAL OF VIROLOGY

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

(2012) Marc D. Panas et al.   MOLECULAR BIOLOGY OF THE CELL

Large G3BP-induced granules trigger eIF2α phosphorylation

(2012) Lucas C. Reineke et al.   MOLECULAR BIOLOGY OF THE CELL

Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity

(2012) Koji Onomoto et al.   PLoS One

The nuclear protein Sam68 is cleaved by the FMDV 3C protease redistributing Sam68 to the cytoplasm during FMDV infection of host cells

(2012) Paul Lawrence et al.   VIROLOGY

MDA5 Detects the Double-Stranded RNA Replicative Form in Picornavirus-Infected Cells

(2012) Qian Feng et al.   Cell Reports

The Leader Proteinase of Foot-and-Mouth Disease Virus Negatively Regulates the Type I Interferon Pathway by Acting as a Viral Deubiquitinase

(2011) D. Wang et al.   JOURNAL OF VIROLOGY

The Leader Protein of Cardioviruses Inhibits Stress Granule Assembly

(2011) F. Borghese et al.   JOURNAL OF VIROLOGY

The Coxsackievirus B 3Cpro Protease Cleaves MAVS and TRIF to Attenuate Host Type I Interferon and Apoptotic Signaling

(2011) Amitava Mukherjee et al.   PLoS Pathogens

Foot-and-mouth disease virus leader proteinase inhibits dsRNA-induced type I interferon transcription by decreasing interferon regulatory factor 3/7 in protein levels

(2010) Dang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Viral security proteins: counteracting host defences

(2010) Vadim I. Agol et al.   NATURE REVIEWS MICROBIOLOGY

Differential IFN-α/β production suppressing capacities of the leader proteins of mengovirus and foot-and-mouth disease virus

(2009) Stanleyson V. Hato et al.   CELLULAR MICROBIOLOGY

RIG-I is cleaved during picornavirus infection

(2009) Paola M. Barral et al.   VIROLOGY